Results 21 to 30 of about 68,097 (255)
Regulation of Skeletal Muscle Atrophy in Cachexia by MicroRNAs and Long Non-coding RNAs
Frontiers in Cell and Developmental Biology, 2020 Skeletal muscle atrophy is a common complication of cachexia, characterized by progressive bodyweight loss and decreased muscle strength, and it significantly increases the risks of morbidity and mortality in the population with atrophy.
Rui Chen +4 more
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Redox control of skeletal muscle atrophy [PDF]
Free Radical Biology and Medicine, 2016 Skeletal muscles comprise the largest organ system in the body and play an essential role in body movement, breathing, and glucose homeostasis. Skeletal muscle is also an important endocrine organ that contributes to the health of numerous body organs.
Scott K. Powers +3 more
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Skeletal Muscle, 2018 Background Denervation triggers numerous molecular responses in skeletal muscle, including the activation of catabolic pathways and oxidative stress, leading to progressive muscle atrophy.
Eva Pigna +7 more
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Herbal complex 'Buyang Huanwu Tang' improves motor endplate function of denervated-dependent skeletal muscle atrophy in rat [PDF]
Journal of Integrative Neuroscience, 2020 Denervated-dependent skeletal muscle atrophy is a disease induced by skeletal muscle associated peripheral neuro-disconnection. Its specific molecular mechanisms remain unknown.
Lan Zhou, Yu-Fang Huang, Hui Xie, Xiao-Yun Mei, Jun Cao
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Pharmaceuticals, 2023 Skeletal muscle atrophy is associated with poor quality of life and disability. Thus, finding a new strategy for the prevention and treatment of skeletal muscle atrophy is very crucial.
Seyedeh Elnaz Nazari +7 more
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Metronidazole Causes Skeletal Muscle Atrophy and Modulates Muscle Chronometabolism [PDF]
International Journal of Molecular Sciences, 2018 Antibiotics lead to increased susceptibility to colonization by pathogenic organisms, with different effects on the host-microbiota relationship. Here, we show that metronidazole treatment of specific pathogen-free (SPF) mice results in a significant increase of the bacterial phylum Proteobacteria in fecal pellets.
Ravikumar Manickam +4 more
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Epigenetic drugs in the treatment of skeletal muscle atrophy [PDF]
Current Opinion in Clinical Nutrition and Metabolic Care, 2008 A dynamic network of anabolic and catabolic pathways regulates skeletal muscle mass in adult organisms. Muscle atrophy is the detrimental outcome of an imbalance of this network. The purpose of this review is to provide a critical evaluation of different forms of muscle atrophy from a mechanistic and therapeutic point of view.The identification and ...
Valentina, Guasconi, Pier Lorenzo, Puri
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Denervation does not induce muscle atrophy through oxidative stress
European Journal of Translational Myology, 2017 Denervation leads to the activation of the catabolic pathways, such as the ubiquitin-proteasome and autophagy, resulting in skeletal muscle atrophy and weakness.
Eva Pigna +10 more
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The role of NLRP3 inflammasome in inflammation-related skeletal muscle atrophy
Frontiers in Immunology, 2022 Skeletal muscle atrophy is a common complication in survivors of sepsis, which affects the respiratory and motor functions of patients, thus severely impacting their quality of life and long-term survival.
Yukun Liu +6 more
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Skeletal Muscle Pathophysiology: The Emerging Role of Spermine Oxidase and Spermidine
Medical Sciences, 2018 Skeletal muscle comprises approximately 40% of the total body mass. Preserving muscle health and function is essential for the entire body in order to counteract chronic diseases such as type II diabetes, cardiovascular diseases, and cancer.
Manuela Cervelli +5 more
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