Protective Effect of Peony (Paeonia ostii) Flower Extract Against Tape Stripping-Induced Skin Barrier Impairment in Mice [PDF]
MoleculesBackground: Skin barrier dysfunction leads to increased transepidermal water loss (TEWL), inflammation, and compromised skin protection. While Paeonia ostii (peony) flowers are recognized in traditional Chinese medicine for their reducing melanin ...
Ruiying Yang +7 more
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Skin Barrier Function: The Interplay of Physical, Chemical, and Immunologic Properties
Cells, 2023 An intact barrier function of the skin is important in maintaining skin health. The regulation of the skin barrier depends on a multitude of molecular and immunological signaling pathways.
Paola Baker +5 more
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Skin-associated adipocytes in skin barrier immunity: A mini-review
Frontiers in Immunology, 2023 The skin contributes critically to health via its role as a barrier tissue against a multitude of external pathogens. The barrier function of the skin largely depends on the uppermost epidermal layer which is reinforced by skin barrier immunity.
Jingyan Guan +3 more
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Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation [PDF]
, 2012 ADAM17 (a disintegrin and metalloproteinase 17) is ubiquitously expressed and cleaves membrane proteins, such as epidermal growth factor receptor (EGFR) ligands, l-selectin, and TNF, from the cell surface, thus regulating responses to tissue injury and ...
Claus-Werner Franzke +9 more
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Diet and Skin Barrier: The Role of Dietary Interventions on Skin Barrier Function
Dermatology Practical & Conceptual, 2021 Multiple research studies have examined the role of specific dietary interventions and their effects on skin barrier function. The skin barrier is one of the body's first lines of protection against environmental insults, and disruption of this natural ...
Milbrey A. Parke +3 more
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SERPINB7 maintains skin barrier by regulating protein O-GalNAc glycosylation [PDF]
Cell Death DiscoveryThe skin barrier is crucial for protecting against environmental challenges, preventing water loss, and regulating immune responses. This study aims to investigate the roles and mechanisms of SERPINB7 in skin barrier maintenance.
Rui Ma +6 more
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Interaction between the microbiota and the skin barrier in aging skin: a comprehensive review
Frontiers in PhysiologyThe interplay between the microbes and the skin barrier holds pivotal significance in skin health and aging. The skin and gut, both of which are critical immune and neuroendocrine system, harbor microbes that are kept in balance.
Yu Ri Woo, Hei Sung Kim
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Skin Barrier Repair and Nursing Care in Patients with Atopic Dermatitis: A Narrative Review [PDF]
International Journal of General MedicineXue Chen School of Medicine, Lishui University, Lishui, Zhejiang, People’s Republic of ChinaCorrespondence: Xue Chen, Email 2665579339@qq.comAbstract: Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disorder characterized by impaired ...
Chen X
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Feeding the Skin Barrier: The Impact of Macro‐ and Micronutrients on Skin Barrier Function [PDF]
Clinical and Translational AllergyBackground Skin is the largest organ of the human body, and acts as a fundamental barrier. Beyond its protective role, it serves as a key immune organ, mediating immune surveillance and regulation.
Klaudia Ryczaj +2 more
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Particulate matter causes skin barrier dysfunction
JCI Insight, 2021 The molecular mechanisms that underlie the detrimental effects of particulate matter (PM) on skin barrier function are poorly understood. In this study, the effects of PM2.5 on filaggrin (FLG) and skin barrier function were investigated in vitro and in ...
Byung Eui Kim +15 more
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