Results 1 to 10 of about 598,588 (305)
Dermatology Research and Practice, 2012 The largest organ of the human body is the skin with its ~2 m2 surface area that envelopes the whole organism defining its physical border and which most importantly provides a barrier against internal organ dehydration and external penetration of noxious substances.
Georgios N. Stamatas +3 more
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Anais Brasileiros de Dermatologia, 2016 Recent studies about the cutaneous barrier demonstrated consistent evidence that the stratum corneum is a metabolically active structure and also has adaptive functions, may play a regulatory role in the inflammatory response with activation of ...
Flavia Alvim Sant'Anna Addor
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SERPINB7 maintains skin barrier by regulating protein O-GalNAc glycosylation [PDF]
Cell Death DiscoveryThe skin barrier is crucial for protecting against environmental challenges, preventing water loss, and regulating immune responses. This study aims to investigate the roles and mechanisms of SERPINB7 in skin barrier maintenance.
Rui Ma +6 more
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Feeding the Skin Barrier: The Impact of Macro‐ and Micronutrients on Skin Barrier Function [PDF]
Clinical and Translational AllergyBackground Skin is the largest organ of the human body, and acts as a fundamental barrier. Beyond its protective role, it serves as a key immune organ, mediating immune surveillance and regulation.
Klaudia Ryczaj +2 more
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Skin Barrier Repair and Nursing Care in Patients with Atopic Dermatitis: A Narrative Review [PDF]
International Journal of General MedicineXue Chen School of Medicine, Lishui University, Lishui, Zhejiang, People’s Republic of ChinaCorrespondence: Xue Chen, Email 2665579339@qq.comAbstract: Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disorder characterized by impaired ...
Chen X
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Chronic kidney disease-associated pruritus: a perspective on skin barrier damage [PDF]
Renal FailureChronic kidney disease-associated pruritus (CKD-aP) is a common complication in patients with end-stage kidney disease (ESKD) that seriously affects quality of life.
Fanzhou Zeng +4 more
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Protective Effect of Peony (Paeonia ostii) Flower Extract Against Tape Stripping-Induced Skin Barrier Impairment in Mice [PDF]
MoleculesBackground: Skin barrier dysfunction leads to increased transepidermal water loss (TEWL), inflammation, and compromised skin protection. While Paeonia ostii (peony) flowers are recognized in traditional Chinese medicine for their reducing melanin ...
Ruiying Yang +7 more
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Autophagy: Guardian of Skin Barrier
Biomedicines, 2022 Autophagy is a major degradation pathway that removes harmful intracellular substances to maintain homeostasis. Various stressors, such as starvation and oxidative stress, upregulate autophagy, and the dysregulation of autophagy is associated with ...
Hyun Jee Kim +5 more
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THE SKIN BARRIER IN SENSITIVE SKIN SYNDROME [PDF]
Journal of IMAB, 2021 Background: Sensitive Skin Syndrome (SSS) is predominantly a self-defined condition without objective pathological findings. The syndrome presents with sudden and easily provoked flushes accompanied by unpleasant sensations like itching, pain or ...
Filka Georgieva
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Journal of Lipid Research, 2022 Desulfation of cholesterol sulfate (CholS) to cholesterol (Chol) is an important event in epidermal homeostasis and necessary for stratum corneum (SC) barrier function.
Ferdinand Fandrei +8 more
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