Results 51 to 60 of about 22,408 (233)

T cells fail to develop in the human skin-cell explants system; an inconvenient truth

open access: yesBMC Immunology, 2011
Background Haplo-identical hematopoietic stem cell (HSC) transplantation is very successful in eradicating haematological tumours, but the long post-transplant T-lymphopenic phase is responsible for high morbidity and mortality rates. Clark et al.
Vanderlocht Joris   +10 more
doaj   +1 more source

Asymmetric patterns of gap junctional communication in developing chicken skin [PDF]

open access: yes, 1993
To study the pattern of gap junctional communication in chicken skin and feather development, we injected Lucifer Yellow into single cells and monitored the transfer of the fluorescent dye through gap junctions.
Chuong, Cheng-Ming   +2 more
core  

Sponge Aquaculture Trials in the East-Mediterranean Sea: New Approaches to Earlier Ideas [PDF]

open access: yes
Aquaculture trials were conducted in the East Aegean Sea with Dysidea avara and Chondrosia reniformis to test the possibility of growing these sponges in the vicinity of sea-based fish farms.
Cerig, E.   +4 more
core   +2 more sources

Skin Punch Biopsy Explant Culture for Derivation of Primary Human Fibroblasts [PDF]

open access: yesJournal of Visualized Experiments, 2013
Tissues and cell lines derived from an individual with disease are ideal sources to study disease-related cellular phenotypes. Patient-derived fibroblasts in this protocol have been successfully used in the derivation of induced pluripotent stem cells to model disease(1).
Malini, Vangipuram   +4 more
openaire   +2 more sources

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng   +16 more
wiley   +1 more source

Wharton’s jelly or bone marrow mesenchymal stromal cells improve cardiac function following myocardial infarction for more than 32 weeks in a rat model: a preliminary report [PDF]

open access: yes, 2013
The therapeutic effect of mesenchymal stromal cells (MSCs) following myocardial infarction (MI) is small. This may be due to differences in cellular sources and donor age, route of administration, in vitro cellular manipulations and the short time course
Borgarelli, Michele   +7 more
core   +2 more sources

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

open access: yesAdvanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones   +14 more
wiley   +1 more source

So, you want to create a frog cell line? A guide to establishing frog skin cell lines from tissue explants

open access: yesMethodsX, 2022
Skin is an important interface with the external environment and investigating amphibian skin cell biology will improve our understanding of how environmental factors such as pathogens and pollutants are contributing to global amphibian declines.
Maxwell P. Bui-Marinos   +3 more
doaj   +1 more source

Calcium oscillations coordinate feather mesenchymal cell movement by SHH dependent modulation of gap junction networks [PDF]

open access: yes, 2018
Collective cell migration mediates multiple tissue morphogenesis processes. Yet how multi-dimensional mesenchymal cell movements are coordinated remains mostly unknown.
Cho, Jung-Hwa   +13 more
core   +5 more sources

Human Skin Explants Recapitulate Key Features of HSV-1 Infections [PDF]

open access: yesJournal of Investigative Dermatology, 2019
The development of novel antiviral compounds is hindered by the lack of model systems that recapitulate the pathophysiology of human infections. Tajpara et al. developed an ex vivo human abdominal skin model of HSV-1 infection to examine host-pathogen interactions and test the efficacy of antiviral compounds.
openaire   +2 more sources

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