Results 31 to 40 of about 12,047 (235)

Mesenchymal stromal cell‐secreted CCL2 promotes antibacterial defense mechanisms through increased antimicrobial peptide expression in keratinocytes

Stem Cells Translational Medicine, 2021
Mesenchymal stromal cells (MSCs) from both humans and horses, which represent a clinically relevant translation animal model for human cutaneous wound healing, were recently found to possess antimicrobial properties against planktonic bacteria, and in ...
Charlotte Marx, Sophia Gardner, Rebecca M. Harman, Bettina Wagner, Gerlinde R. Van de Walle   +4 more
doaj   +1 more source

An Optimized Tissue Dissociation Protocol for Single-Cell RNA Sequencing Analysis of Fresh and Cultured Human Skin Biopsies

Frontiers in Cell and Developmental Biology, 2022
We present an optimized dissociation protocol for preparing high-quality skin cell suspensions for in-depth single-cell RNA-sequencing (scRNA-seq) analysis of fresh and cultured human skin. Our protocol enabled the isolation of a consistently high number
Blaž Burja, Blaž Burja, Blaž Burja, Dominique Paul, Aizhan Tastanova, Sam G. Edalat, Reto Gerber, Reto Gerber, Miranda Houtman, Muriel Elhai, Kristina Bürki, Ramon Staeger, Gaetana Restivo, Ramon Lang, Snezna Sodin-Semrl, Katja Lakota, Matija Tomšič, Matija Tomšič, Mitchell P. Levesque, Oliver Distler, Žiga Rotar, Žiga Rotar, Mark D. Robinson, Mojca Frank-Bertoncelj, Mojca Frank-Bertoncelj   +24 more
doaj   +1 more source

Reprogramming of one human induced pluripotent stem cell line from healthy donor

Stem Cell Research, 2021
In this study, skin biopsy was, and the fibroblasts were isolated from the dermal explant cultures. Human induced pluripotent stem cell (iPSC) line was generated from the skin fibroblasts collected from a healthy 50-year old male donor with informed ...
Shuxing Cao, Jun Ma, Jinyu Zhang, Ruiyun Guo, Xin Liu, Ming Li   +5 more
doaj   +1 more source

In vitro modeling of amyotrophic lateral sclerosis with induced pluripotent stem cell technology-derived cell line ORIONi002-A

Stem Cell Research, 2022
We present here a new iPS cell line for modeling sporadic form of ALS. Cell line was generated by reprogramming skin fibroblasts isolated with explant culture technology from skin biopsy, donated by ALS patient.
Jan Strnadel, Hugo M. Dumortier, Dominika Hajduchova, Romana Zahumenska, Vladimir Nosal, Marek Smolar, Juraj Marcinek, Michal Kalman, Sandra Mersakova, Dusan Brany, Stefan Juhas, Jana Juhasova, Hana Studenovska, Barbora Mitruskova, Stanislava Suroviakova, Slavomira Novakova, Henrieta Skovierova, Egon Kurca, Renata Pecova, Lukas Plank, Erika Halasova   +20 more
doaj   +1 more source

Usefulness of Skin Explants for Histologic Analysis after Fractional Photothermolysis [PDF]

Annals of Dermatology, 2015
Fractional laser resurfacing treatment has been extensively investigated and is widely used. However, the mechanism underlying its effects is poorly understood because of the ethical and cosmetic problems of obtaining skin biopsies required to study the changes after laser treatment.To evaluate the usefulness of human skin explants for the ...
Gyeong-Hun Park, Sung Eun Chang, Seunghyun Bang, Kwang Hee Won, Chong Hyun Won, Mi Woo Lee, Jee Ho Choi, Kee Chan Moon   +7 more
openaire   +2 more sources

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Development of a Skin Explant Model for Studying UV-induced DNA damage

, 2023
Current skin models in research do not accurately represent the skin.
Payne, Hailey
core  

Clinical Efficacy of Adiponectin-Stimulating Peptide on UV-Induced Skin Damage

Cosmetics
Several studies have suggested that adiponectin is an anti-aging molecule based on its potential involvement of adipose tissue in skin aging. In this study, we investigated the anti-photoaging efficacy of an adiponectin expression-stimulating peptide ...
Yongwoo Kim, Seokjeong Yoon, Sungwoo Kim, Yeonjae Kim, Sekyoo Jeong, Hyun-jung Kim   +5 more
doaj   +1 more source

Biological Effects of Maslinic Acid on Human Epithelial Cells Used in Tissue Engineering

Frontiers in Bioengineering and Biotechnology, 2022
In the present work, we evaluated the potential of maslinic acid (MA) to improve currently available keratinocyte culture methods for use in skin tissue engineering.
Olimpia Ortiz-Arrabal, Olimpia Ortiz-Arrabal, Olimpia Ortiz-Arrabal, Jesús Chato-Astrain, Jesús Chato-Astrain, Pascual Vicente Crespo, Pascual Vicente Crespo, Ingrid Garzón, Ingrid Garzón, María Dolores Mesa-García, María Dolores Mesa-García, María Dolores Mesa-García, Miguel Alaminos, Miguel Alaminos, Carolina Gómez-Llorente, Carolina Gómez-Llorente, Carolina Gómez-Llorente   +16 more
doaj   +1 more source

Comparison of the metabolism of 10 chemicals in human and pig skin explants [PDF]

Journal of Applied Toxicology, 2018
AbstractSkin metabolism is important to consider when assessing local toxicity and/or penetration of chemicals and their metabolites. If human skin supply is limited, pig skin can be used as an alternative. To identify any species differences, we have investigated the metabolism of 10 chemicals in a pig and human skin explant model.
Genies, Camille, Jamin, Emilien L., Debrauwer, Laurent, Zalko, Daniel, Person, Elodie N., Eilstein, J., Gregoire, S., Schepky, A., Lange, D., Ellison, C., Roe, A., Salhi, S., Cubberley, R., Hewitt, N. J., Rothe, H., Klaric, M., Duplan, H., Jacques-Jamin, C.   +17 more
openaire   +4 more sources