Results 81 to 90 of about 1,942 (174)
Dietary Patterns and Risk of Colorectal Cancer Subtypes Classified by Fusobacterium nucleatum in Tumor Tissue [PDF]
Importance—Fusobacterium nucleatum appears to play a role in colorectal carcinogenesis through suppression of host immune response to tumor. Evidence also suggests that diet influences intestinal F. nucleatum. However, the role of F.
Bullman, Susan +23 more
core +1 more source
ABSTRACT Primary hypertrophic osteoarthropathy (Pachydermoperiostosis) is a rare, inherited genetic disorder of the skeleton and the skin, characterised by clubbing of the fingers, thickening of the skin especially of the face and forehead (pachydermia) and periostosis. Patients often present with pain and swelling of the knees and ankles.
Ahmed AbdulBari +3 more
wiley +1 more source
ABSTRACT Background and Aims The long‐term outcomes of enteroscopic balloon dilation for small bowel strictures in patients with Crohn’s disease are not well understood. Although Crohn’s strictures can be classified into web‐like, ulcerated, and spindle‐shaped strictures based on endoscopic findings, the outcomes of enteroscopic balloon dilation ...
Sung Noh Hong +4 more
wiley +1 more source
ABSTRACT Primary Hypertrophic Osteoarthropathy (PHOAR1) is characterized by autosomal recessive loss of function variants in 15‐hydroxyprostaglandin dehydrogenase (HPGD) leading to digital clubbing, periostosis, pachydermia, and severe hyperhidrosis. HPGD catalyzes the first step of prostaglandin E2 (PGE2) degradation.
Kara Zehr +6 more
wiley +1 more source
The organic anion transporter OAT4 (SLC22A11) and organic anion transporting polypeptide OATP2B1 (SLCO2B1) are expressed in the basal membrane of the placental syncytiotrophoblast.
Brooks, S. +6 more
core +1 more source
Spontaneous Transformation of Murine Oviductal Epithelial Cells: A Model System to Investigate the Onset of Fallopian-Derived Tumors [PDF]
High-grade serous carcinoma (HGSC) is the most lethal ovarian cancer histotype. The fallopian tube secretory epithelial cells (FTSECs) are a proposed progenitor cell type.
Daniel D. Lantvit +6 more
core +2 more sources
It is increasingly recognized that young, chow‐fed inbred mice poorly model the complexity of human carcinogenesis in multiple respects. In humans, age and adiposity are the major risk factors for the majority of malignancies. Although the development of genetically engineered mouse models (GEMM) of cancer has recapitulated many aspects of human cancer,
Iqbal M. Lone +4 more
wiley +1 more source
Phenotypic and pharmacogenetic evaluation of patients with thiazide-induced hyponatremia. [PDF]
Thiazide diuretics are among the most widely used treatments for hypertension, but thiazide-induced hyponatremia (TIH), a clinically significant adverse effect, is poorly understood.
Amanda P. Henry +24 more
core +6 more sources
A Narrative Review on the Effect of Valproic Acid on the Placenta
ABSTRACT Background Valproic acid (VPA) is an antiepileptic and mood‐stabilizing drug with well‐established teratogenic risks when taken during pregnancy. While its harmful effects on fetal development are well known, less attention has been given to its impact on placental development and function, despite the placenta's critical role in pregnancy ...
Lauren T. L. Brown +2 more
wiley +1 more source
Association of EP2 receptor and SLC19A3 in regulating breast cancer metastasis [PDF]
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Chen, J +8 more
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