Results 111 to 120 of about 217,308 (243)

What’s new in medical renal pathology 2025: Updates on podocytopathy and immunofluorescence staining in medical kidney [PDF]

open access: yesJournal of Pathology and Translational Medicine
Diffuse podocytopathy, including minimal change disease and primary focal segmental glomerulosclerosis, is a common cause of nephrotic syndrome in adults and children.
Astrid Weins   +9 more
doaj   +1 more source

FMRI Approaches to Mapping Cerebrovascular Reactivity: Comparison of Gradient Echo BOLD and Spin Echo BOLD With Arterial Spin Labeling

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To compare markers of cerebrovascular reactivity (CVR) measured with Gradient Echo (GE, T2*w) and Spin‐Echo (SE, T2w) BOLD fMRI with quantitative physiological CVR measured using ASL. Methods CVR, the ability of blood vessels to dilate and increase cerebral blood flow (CBF), can be investigated with ASL fMRI but has a low signal‐to ...
Sara Pomante   +13 more
wiley   +1 more source

Free‐Breathing Magnetization Transfer Imaging of the Lung at 0.55 T Using bSTAR

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop a clinically applicable method for magnetization transfer (MT) imaging of the lung at 0.55 T. Methods MT imaging of the chest was explored in healthy volunteers at 0.55 T using a self‐gated 3D half‐radial dual‐echo balanced steady‐state free precession sequence (bSTAR), a 2D multi‐slice gradient echo method (GRE) acquired in
Alexandra Braun   +5 more
wiley   +1 more source

Regulation of the Actin Cytoskeleton in Podocytes

open access: yesCells, 2020
Podocytes are an integral part of the glomerular filtration barrier, a structure that prevents filtration of large proteins and macromolecules into the urine.
Judith Blaine, James Dylewski
doaj   +1 more source

6‐Shogaol Attenuates Doxorubicin‐Induced Cardiac and Skeletal Muscle Atrophy by Inhibiting E3 Ubiquitin Ligases and Necroptosis

open access: yesPhytotherapy Research, EarlyView.
Doxorubicin induces cardiac and skeletal muscle atrophy by upregulating E3 ubiquitin ligases, inhibiting myogenic regulatory factors, and activating necroptosis. Cardiac atrophy can further exacerbate cardiotoxicity. 6‐Shogaol negatively regulates these processes and attenuates doxorubicin‐induced cardiac and skeletal muscle atrophy.
Xipeng Sun   +5 more
wiley   +1 more source

Photodegradable Hydrogels for On‐Demand Modeling of Age‐Related Spatiotemporal ECM Deformation

open access: yesSmall, EarlyView.
A light‐tunable PEG hydrogel enables on‐demand, spatiotemporal modeling of drusen‐like ECM bulges in the aging outer retina. By precisely controlling bulge size, the platform reveals how retinal pigment epithelium morphology adapts to topographical changes without disrupting actin cytoskeleton or polarity, effectively mimicking early ageing before ...
Felix Reul   +8 more
wiley   +1 more source

Image Slicer Performances from a Demonstrator for the SNAP/JDEM Mission - Part I: Wavelength Accuracy

open access: yes, 2008
A well-adapted visible and infrared spectrograph has been developed for the SNAP (SuperNova/Acceleration Probe) experiment proposed for JDEM. The instrument should have a high sensitivity to see faint supernovae but also a good redshift determination ...
Aumeunier, M-H.   +4 more
core   +3 more sources

Congenital aniridia: European COST action ANIRIDIA‐NET guidelines for diagnosis, management and care

open access: yesActa Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare ocular disorder affecting the majority of eye structures and can be associated with systemic manifestations. The main visible phenotypic characteristic is the partial or complete absence of the iris; however, foveal hypoplasia is a more frequent and reliable clinical sign. Other ocular comorbidities are associated
Davide Romano   +26 more
wiley   +1 more source

Par-6-ephrin-B1 interaction is regulated by nephrin-mediated signal and is crucial in maintaining slit diaphragm of podocyte.

open access: yesAmerican Journal of Pathology, 2019
Ephrin-B1 plays a critical role at slit diaphragm. Par-6 is down-regulated in podocyte of ephrin-B1 KO mouse, suggesting that Par-6 is associated with ephrin-B1.
Sayuri Takamura   +4 more
semanticscholar   +1 more source

Optical design of the SOXS spectrograph for ESO NTT

open access: yes, 2018
An overview of the optical design for the SOXS spectrograph is presented. SOXS (Son Of X-Shooter) is the new wideband, medium resolution (R>4500) spectrograph for the ESO 3.58m NTT telescope expected to start observations in 2021 at La Silla.
Achrén, Jani   +50 more
core   +1 more source

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