Results 11 to 20 of about 16,909 (206)

A phospho-switch to trigger mitotic chromosome condensation [PDF]

Biology Direct
One of the most eye-catching events in cell biology is the condensation of chromosomes. During mitosis, the diffuse interphase chromatin rearranges into compact, rod-shaped chromosomes that can be precisely segregated between the daughter cells.
Alessandro Borsellini
doaj   +2 more sources

A low Smc flux avoids collisions and facilitates chromosome organization in Bacillus subtilis

eLife, 2021
SMC complexes are widely conserved ATP-powered DNA-loop-extrusion motors indispensable for organizing and faithfully segregating chromosomes. How SMC complexes translocate along DNA for loop extrusion and what happens when two complexes meet on the same ...
Anna Anchimiuk, Virginia S Lioy, Florian Patrick Bock, Anita Minnen, Frederic Boccard, Stephan Gruber   +5 more
doaj   +1 more source

An SMC-like protein binds and regulates Caenorhabditis elegans condensins. [PDF]

PLoS Genetics, 2017
Structural Maintenance of Chromosomes (SMC) family proteins participate in multisubunit complexes that govern chromosome structure and dynamics.
Lucy Fang-I Chao, Meha Singh, James Thompson, John R Yates, Kirsten A Hagstrom   +4 more
doaj   +1 more source

Structural Insights into Ring Formation of Cohesin and Related Smc Complexes

Trends in Cell Biology, 2016
Jan Lowe, Thomas Gligoris
exaly   +2 more sources

Testing pseudotopological and nontopological models for SMC-driven DNA loop extrusion against roadblock-traversal experiments

Scientific Reports, 2023
DNA loop extrusion by structural-maintenance-of-chromosome (SMC) complexes has emerged as a primary organizing principle for chromosomes. The mechanism by which SMC motor proteins extrude DNA loops is still unresolved and much debated.
Roman Barth, Biswajit Pradhan, Eugene Kim, Iain F. Davidson, Jaco van der Torre, Jan-Michael Peters, Cees Dekker   +6 more
doaj   +1 more source

The loopy world of cohesin

eLife, 2021
DNA loops can be formed by a mechanism in which the cohesin complex pulls DNA strands through its ring structure using biased Brownian motion.
Kazuhiro Maeshima, Shiori Iida
doaj   +1 more source

DYNAMIC PHYSICAL-GEOLOGICAL MODEL OF THE FIELD OF DIAMONDS FROM THE KOMSOMOLSKAYA KIMBERLITE PIPE (ALAKIT-MARKHA FIELD OF WESTERN YAKUTIA)

Геодинамика и тектонофизика, 2022
Petrophysical, tectonophysical and paleomagnetic studies were done on the field of diamonds from the Komsomolskaya kimberlite pipe to interpret the observed gravimagnetic field. As a result of studying the structural-material complexes (SMC) of the field,
K. M. Konstantinov, A. S. Gladkov
doaj   +1 more source

Chromosome organization by one-sided and two-sided loop extrusion

eLife, 2020
SMC complexes, such as condensin or cohesin, organize chromatin throughout the cell cycle by a process known as loop extrusion. SMC complexes reel in DNA, extruding and progressively growing DNA loops.
Edward J Banigan, Aafke A van den Berg, Hugo B Brandão, John F Marko, Leonid A Mirny   +4 more
doaj   +1 more source

Taking cohesin and condensin in context.

PLoS Genetics, 2018
Structural maintenance of chromosome (SMC) protein complexes, including cohesin and condensin, are increasingly being recognized for their important role in cancer and development, making it critical that we understand how these evolutionarily conserved ...
Kobe C Yuen, Jennifer L Gerton
doaj   +1 more source

MukB ATPases are regulated independently by the N- and C-terminal domains of MukF kleisin

eLife, 2018
The Escherichia coli SMC complex, MukBEF, acts in chromosome segregation. MukBEF shares the distinctive architecture of other SMC complexes, with one prominent difference; unlike other kleisins, MukF forms dimers through its N-terminal domain.
Katarzyna Zawadzka, Pawel Zawadzki, Rachel Baker, Karthik V Rajasekar, Florence Wagner, David J Sherratt, Lidia K Arciszewska   +6 more
doaj   +1 more source