Results 41 to 50 of about 8,854,464 (148)
Molecular basis for SMC rod formation and its dissolution upon DNA binding. [PDF]
, 2015 SMC condensin complexes are central modulators of chromosome superstructure in all branches of life. Their SMC subunits form a long intramolecular coiled coil, which connects a constitutive "hinge" dimerization domain with an ATP-regulated "head ...
Soh, Young-Min +69 more
core +1 more source
Taking cohesin and condensin in context.
PLoS Genetics, 2018 Structural maintenance of chromosome (SMC) protein complexes, including cohesin and condensin, are increasingly being recognized for their important role in cancer and development, making it critical that we understand how these evolutionarily conserved ...
Kobe C Yuen, Jennifer L Gerton
doaj +1 more source
MukB ATPases are regulated independently by the N- and C-terminal domains of MukF kleisin
eLife, 2018 The Escherichia coli SMC complex, MukBEF, acts in chromosome segregation. MukBEF shares the distinctive architecture of other SMC complexes, with one prominent difference; unlike other kleisins, MukF forms dimers through its N-terminal domain.
Katarzyna Zawadzka +6 more
doaj +1 more source
Molecules, 2020 New mesomorphic symmetrical 2:1 supramolecular H-bonded complexes of seven phenyl rings were prepared between 4-n-alkoxyphenylazobenzoic acids and 4-(2-(pyridin-3-yl)diazenyl)phenyl nicotinate.
Laila A. Al-Mutabagani +4 more
doaj +1 more source
A role of the Nse4 kleisin and Nse1/Nse3 KITE subunits in the ATPase cycle of SMC5/6
Scientific Reports, 2020 The SMC (Structural Maintenance of Chromosomes) complexes are composed of SMC dimers, kleisin and kleisin-interacting (HAWK or KITE) subunits. Mutual interactions of these subunits constitute the basal architecture of the SMC complexes.
Lucie Vondrova +5 more
doaj +1 more source
Condensin Smc2-Smc4 Dimers Are Flexible and Dynamic
Cell Reports, 2016 Structural maintenance of chromosomes (SMC) protein complexes, including cohesin and condensin, play key roles in the regulation of higher-order chromosome organization.
Jorine M. Eeftens +7 more
doaj +1 more source
Competitive binding of MatP and topoisomerase IV to the MukB hinge domain
eLife, 2021 Structural Maintenance of Chromosomes (SMC) complexes have ubiquitous roles in compacting DNA linearly, thereby promoting chromosome organization-segregation.
Gemma LM Fisher +10 more
doaj +1 more source
Role of Structural Maintenance of Chromosomes (SMC) complexes in interphase genome folding in Caenorhabditis elegans [PDF]
, 2022 Recent studies have shown that the highly conserved Structural Maintenance of Chromosomes (SMC) complexes such as cohesin and condensin, are involved in organizing the interphase genome.
Das, Moushumi
core
DNA sliding and loop formation by E. coli SMC complex: MukBEF
Biochemistry and Biophysics Reports, 2022 SMC (structural maintenance of chromosomes) complexes share conserved architectures and function in chromosome maintenance via an unknown mechanism. Here we have used single-molecule techniques to study MukBEF, the SMC complex in Escherichia coli.
Man Zhou
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SMC complexes and topoisomerase II work together so that sister chromatids can work apart
Cell Cycle, 2010 The pairing of sister chromatids in interphase facilitates error-free homologous recombination (HR). Sister chromatids are held together by cohesin, one of three Structural Maintenance of Chromosomes (SMC) complexes.
Claudia Tapia-Alveal +5 more
semanticscholar +3 more sources