Results 21 to 30 of about 16,449 (234)
The bacterial chromosome: architecture and action of bacterial SMC and SMC-like complexes [PDF]
FEMS Microbiology Reviews, 2014 Structural Maintenance of Chromosomes (SMC) protein complexes are found in all three domains of life. They are characterized by a distinctive and conserved architecture in which a globular ATPase 'head' domain is formed by the N- and C-terminal regions of the SMC protein coming together, with a c. 50-nm-long antiparallel coiled-coil separating the head
Nolivos, Sophie, Sherratt, David
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Analysis of the Chromosomal Localization of Yeast SMC Complexes by Chromatin Immunoprecipitation. [PDF]
Methods Mol Biol, 2019 A plethora of biological processes like gene transcription, DNA replication, DNA recombination, and chromosome segregation are mediated through protein-DNA interactions. A powerful method for investigating proteins within a native chromatin environment in the cell is chromatin immunoprecipitation (ChIP).
Makrantoni V, Robertson D, Marston AL.
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Scientific Reports, 2023 DNA loop extrusion by structural-maintenance-of-chromosome (SMC) complexes has emerged as a primary organizing principle for chromosomes. The mechanism by which SMC motor proteins extrude DNA loops is still unresolved and much debated.
Roman Barth +6 more
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eLife, 2021 DNA loops can be formed by a mechanism in which the cohesin complex pulls DNA strands through its ring structure using biased Brownian motion.
Kazuhiro Maeshima, Shiori Iida
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Геодинамика и тектонофизика, 2022 Petrophysical, tectonophysical and paleomagnetic studies were done on the field of diamonds from the Komsomolskaya kimberlite pipe to interpret the observed gravimagnetic field. As a result of studying the structural-material complexes (SMC) of the field,
K. M. Konstantinov, A. S. Gladkov
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Chromosome organization by one-sided and two-sided loop extrusion
eLife, 2020 SMC complexes, such as condensin or cohesin, organize chromatin throughout the cell cycle by a process known as loop extrusion. SMC complexes reel in DNA, extruding and progressively growing DNA loops.
Edward J Banigan +4 more
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Towards a Unified Model of SMC Complex Function [PDF]
Current Biology, 2018 Protein complexes built of structural maintenance of chromosomes (SMC) and kleisin subunits, including cohesin, condensin and the Smc5/6 complex, are master organizers of genome architecture in all kingdoms of life. How these large ring-shaped molecular machines use the energy of ATP hydrolysis to change the topology of chromatin fibers has remained a ...
Hassler, Markus +2 more
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Taking cohesin and condensin in context.
PLoS Genetics, 2018 Structural maintenance of chromosome (SMC) protein complexes, including cohesin and condensin, are increasingly being recognized for their important role in cancer and development, making it critical that we understand how these evolutionarily conserved ...
Kobe C Yuen, Jennifer L Gerton
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MukB ATPases are regulated independently by the N- and C-terminal domains of MukF kleisin
eLife, 2018 The Escherichia coli SMC complex, MukBEF, acts in chromosome segregation. MukBEF shares the distinctive architecture of other SMC complexes, with one prominent difference; unlike other kleisins, MukF forms dimers through its N-terminal domain.
Katarzyna Zawadzka +6 more
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Molecules, 2020 New mesomorphic symmetrical 2:1 supramolecular H-bonded complexes of seven phenyl rings were prepared between 4-n-alkoxyphenylazobenzoic acids and 4-(2-(pyridin-3-yl)diazenyl)phenyl nicotinate.
Laila A. Al-Mutabagani +4 more
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