Results 21 to 30 of about 16,909 (206)

New Symmetrical U- and Wavy-Shaped Supramolecular H-Bonded Systems; Geometrical and Mesomorphic Approaches

open access: yesMolecules, 2020
New mesomorphic symmetrical 2:1 supramolecular H-bonded complexes of seven phenyl rings were prepared between 4-n-alkoxyphenylazobenzoic acids and 4-(2-(pyridin-3-yl)diazenyl)phenyl nicotinate.
Laila A. Al-Mutabagani   +4 more
doaj   +1 more source

A role of the Nse4 kleisin and Nse1/Nse3 KITE subunits in the ATPase cycle of SMC5/6

open access: yesScientific Reports, 2020
The SMC (Structural Maintenance of Chromosomes) complexes are composed of SMC dimers, kleisin and kleisin-interacting (HAWK or KITE) subunits. Mutual interactions of these subunits constitute the basal architecture of the SMC complexes.
Lucie Vondrova   +5 more
doaj   +1 more source

Condensin Smc2-Smc4 Dimers Are Flexible and Dynamic

open access: yesCell Reports, 2016
Structural maintenance of chromosomes (SMC) protein complexes, including cohesin and condensin, play key roles in the regulation of higher-order chromosome organization.
Jorine M. Eeftens   +7 more
doaj   +1 more source

Competitive binding of MatP and topoisomerase IV to the MukB hinge domain

open access: yeseLife, 2021
Structural Maintenance of Chromosomes (SMC) complexes have ubiquitous roles in compacting DNA linearly, thereby promoting chromosome organization-segregation.
Gemma LM Fisher   +10 more
doaj   +1 more source

DNA sliding and loop formation by E. coli SMC complex: MukBEF

open access: yesBiochemistry and Biophysics Reports, 2022
SMC (structural maintenance of chromosomes) complexes share conserved architectures and function in chromosome maintenance via an unknown mechanism. Here we have used single-molecule techniques to study MukBEF, the SMC complex in Escherichia coli.
Man Zhou
doaj   +1 more source

Distinct Activities of Bacterial Condensins for Chromosome Management in Pseudomonas aeruginosa

open access: yesCell Reports, 2020
Summary: Three types of structurally related structural maintenance of chromosomes (SMC) complexes, referred to as condensins, have been identified in bacteria.
Virginia S. Lioy   +4 more
doaj   +1 more source

Finding small molecular compounds to decrease trimethylamine oxide levels in atherosclerosis by virtual screening

open access: yesOpen Chemistry, 2023
The intestinal microbial metabolite trimethylamine oxide (TMAO) affects the formation and development of atherosclerosis (AS). The design and development of an effective targeted drug to reduce serum TMAO levels may provide new avenues for inhibiting AS ...
Luo Jiaxin   +3 more
doaj   +1 more source

Spo0J and SMC are required for normal chromosome segregation in Staphylococcus aureus

open access: yesMicrobiologyOpen, 2020
Bacterial chromosome segregation is an essential cellular process that is particularly elusive in spherical bacteria such as the opportunistic human pathogen Staphylococcus aureus.
Helena Chan   +2 more
doaj   +1 more source

Dynamic assembly, localization and proteolysis of the Bacillus subtilis SMC complex

open access: yesBMC Cell Biology, 2005
Background SMC proteins are key components of several protein complexes that perform vital tasks in different chromosome dynamics. Bacterial SMC forms a complex with ScpA and ScpB that is essential for chromosome arrangement and segregation.
Rinn Cornelia   +5 more
doaj   +1 more source

Three-dimensional topology of the SMC2/SMC4 subcomplex from chicken condensin I revealed by cross-linking and molecular modelling [PDF]

open access: yesOpen Biology, 2015
SMC proteins are essential components of three protein complexes that are important for chromosome structure and function. The cohesin complex holds replicated sister chromatids together, whereas the condensin complex has an essential role in mitotic ...
Helena Barysz   +6 more
doaj   +1 more source

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