Results 41 to 50 of about 554,561 (350)
Altered functional properties of the codling moth Orco mutagenized in the intracellular loop-3
Scientific Reports, 2021 Amino acid substitutions within the conserved polypeptide sequence of the insect olfactory receptor co-receptor (Orco) have been demonstrated to influence its pharmacological properties.
Yuriy V. Bobkov +2 more
doaj +1 more source
On the Feasibility of Transfer-learning Code Smells using Deep Learning
, 2019 Context: A substantial amount of work has been done to detect smells in source code using metrics-based and heuristics-based methods. Machine learning methods have been recently applied to detect source code smells; however, the current practices are ...
Efstathiou, Vasiliki +3 more
core +1 more source
Combined electronic nose and tongue for a flavour sensing system [PDF]
, 2011 We present a novel, smart sensing system developed for the flavour analysis of liquids. The system comprises both a so-called "electronic tongue" based on shear horizontal surface acoustic wave (SH-SAW) sensors analysing the liquid phase and a so-called "
Cole, Marina +2 more
core +1 more source
Time–frequency analysis of gustatory event related potentials (gERP) in taste disorders
Scientific ReportsIn taste disorders, the key to a correct diagnosis and an adequate treatment is an objective assessment. Compared to psychophysical tests, EEG-derived gustatory event-related potentials (gERP) could be used as a less biased measure.
Mariano Mastinu +5 more
doaj +1 more source
Scientific Reports, 2017 The clinical diagnostics of olfactory dysfunction in children turns out to be challenging due to low attention span, insufficient linguistic development and lack of odor experiences. Several smell tests have been developed for adults.
Janine Gellrich +4 more
doaj +1 more source
Frontiers in Neuroscience, 2021 Purpose of ReviewOlfactory dysfunction dramatically impairs quality of life with a prevalence of 20% in the general adult population. Psychophysical olfactory testing has been widely used to evaluate the ability to smell due to its validated utility and ...
Baihan Su +4 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Functional connectivity patterns in parosmia
Behavioral and Brain Functions, 2023 Objective Parosmia is a qualitative olfactory dysfunction presenting as “distorted odor perception” in presence of an odor source. Aim of this study was to use resting state functional connectivity to gain more information on the alteration of olfactory ...
Divesh Thaploo +5 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source