Results 91 to 100 of about 5,400 (185)
Bilateral Gonadoblastoma in a 12‐Year‐Old Girl 4 Years After Wilms' Tumor: A Rare Pediatric Case
ABSTRACT This case of a 12‐year‐old patient who developed bilateral gonadoblastoma 4 years after treatment for Wilms tumor highlights the importance of rigorous, risk‐adapted long‐term surveillance and careful evaluation of incidental gonadal findings, even in asymptomatic patients.
Ahmed Quraish +4 more
wiley +1 more source
Functional Brain Network Predictors of Abstinence Treatment Outcomes in Methamphetamine Use Disorder
Baseline whole‐brain functional connectivity predicted 1‐year abstinence response in methamphetamine use disorder at the individual level. Multi‐level network analyses revealed distinct response‐related connectivity patterns involving control‐related circuits.
Yanyao Du +10 more
wiley +1 more source
Structural studies of the SMN-Gemin2 complex
The proteins SMN and Gemin2 form the conserved core of the larger eponymous SMN complex, which also contains Gemins3-8 and unrip in an unknown stoichiometry.
Sarachan, Kathryn Lorenz
core
Graphical abstract showing nanoencapsulation‐based yogurt fortification, highlighting nanocarrier incorporation, improved storage stability, enhanced bioaccessibility, targeted gastrointestinal release, nutrient absorption, and gut microbiota modulation.
Farhang Hameed Awlqadr +8 more
wiley +1 more source
Childhood spinal muscular atrophy (SMA) is caused by a reduction in survival motor neuron (SMN) protein. SMN is a ubiquitously expressed house keeping protein that is involved in RNA production and processing.
Shaw, Debra J. +9 more
core +1 more source
Gallic acid (GA) dose‐dependently reduced sleep latency and prolonged sleep duration in thiopental sodium‐induced mice, with synergistic effects when combined with diazepam. Molecular docking revealed GA's higher binding affinity (−9.8 kcal/mol) to GABAA receptor (α1 and β2 subunits) than diazepam (−8.4 kcal/mol), suggesting GABAergic potential ...
Noshin Tasnim Yana +13 more
wiley +1 more source
Friend of Prmt1, FOP is a novel component of the nuclear SMN complex isolated using biotin affinity purification [PDF]
SMN (survival motor neuron protein) complexes are essential for the biogenesis of uridine-rich small nuclear ribonucleoproteins (UsnRNPs). During the biogenesis, the SMN complexes bound to UsnRNPs are transported from the cytoplasm to the nucleus, and ...
Yamauchi, N. (Naoto) +11 more
core +1 more source
Spinal muscular atrophy is an autosomal recessive neurodegenerative disease of childhood, resulting from deletion or mutation of the survival motor neuron ( SMN ) gene on chromosome 5q13.
Mohaghegh, P +6 more
core +1 more source
ABSTRACT Background Inflammatory pain is a widespread global health concern arising from complex molecular pathways triggered by a consequence of tissue damage and immune activation. It significantly impacts quality of life and functional outcomes, necessitating a comprehensive understanding of underlying mechanisms and multidisciplinary approaches for
Fatma Mohamed Elmansy +6 more
wiley +1 more source
Arginine methylation in subunits of mammalian pre-mRNA cleavage factor I [PDF]
Mammalian cleavage factor I (CF Im) is composed of two polypeptides of 25 kDa and either a 59 or 68 kDa subunit (CF Im25, CF Im59, CF Im68). It is part of the cleavage and polyadenylation complex responsible for processing the 39 ends of messenger RNA ...
Antje Ostareck-Lederer +26 more
core +1 more source

