Results 91 to 100 of about 10,068 (192)

The Illness Narratives of Children and Young People With Spinal Muscular Atrophy: A Scoping Review

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim(s) This review seeks to explore the illness narratives of children and young people focusing on their healthcare trajectories; the right to health; and the kind of stories told about them. Design This scoping review adopts a narrative approach to analyse how the illness experience of Spinal Muscular Atrophy is represented in the literature,
Marcela González‐Agüero, Constanza Quezada, Valentina Turén, Josefa Camelio, Martina De Filippi, Caroline Bradbury‐Jones, Julie Taylor   +6 more
wiley   +1 more source

Use of RNA secondary structure for evolutionary relationships : investigating RNase P and RNase MRP : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Genetics at Massey University, New Zealand [PDF]

, 1998
Bioinformatics is applied here to examine whether RNA secondary structure data can reflect distant evolutionary relationships. This is important when there is little confidence in sequence data such as when looking at the evolution of RNase MRP (MRP ...
Collins, Lesley Joan
core  

RNA-sequencing of a mouse-model of spinal muscular atrophy reveals tissue-wide changes in splicing of U12-dependent introns [PDF]

, 2016
Spinal Muscular Atrophy (SMA) is a neuromuscular disorder caused by insufficient levels of the Survival of Motor Neuron (SMN) protein. SMN is expressed ubiquitously and functions in RNA processing pathways that include trafficking of mRNA and assembly of
Andersen, H. S., Andresen, B. S., Broner, S., Bruun, G. H., Dembic, M., Doktor, T. K., Hua, Y., Krainer, A. R., Liu, Y. H., Wieckowska, A.   +9 more
core   +2 more sources

The variability of giraffe skull morphology

Journal of Anatomy, EarlyView.
What does giraffe skull shape tell us about their development and evolution? Abstract Giraffe (Giraffa spp.) are among the most unique and charismatic extant animals, largely due to their distinct morphology. The evolutionary and developmental origin of ossicones is a key factor in giraffid biology, yet other features building their characteristic head
Nikolaos Kargopoulos, Jesús Marugán‐Lobón, Anusuya Chinsamy‐Turan, Bernard R. Agwanda, Michael Butler Brown, Stephanie Fennessy, Sara Ferguson, Rigardt Hoffman, Fredrick Lala, Arthur Muneza, Ogeto Mwebi, Moses Otiende, Alice Petzold, Sven Winter, Abdoul Razack Moussa Zabeirou, Julian Fennessy   +15 more
wiley   +1 more source

Cellular immune response of Amblyomma sculptum and Amblyomma americanum to entomopathogenic fungi: Implications for biological tick control

Medical and Veterinary Entomology, EarlyView.
Amblyomma sculptum showed a plasmatocyte‐dominant haemocyte profile. Beauveria bassiana increased plasmatocytes and reduced granulocytes, whereas Metarhizium robertsii did not cause significant changes. Amblyomma americanum showed a granulocyte‐dominant haemocyte profile. Beauveria bassiana reduced total haemocytes and granulocytes. B.
Cárita de Souza Ribeiro‐Silva, Valesca Henrique Lima, Salorrane Miranda N. Pinto, Gustavo Felizardo S. Sandes, Victor Hugo Ribeiro Costa, Albert Mulenga, Adela S. Oliva Chavez, Éverton Kort Kamp Fernandes   +7 more
wiley   +1 more source

Loss-of-function genetic diseases and the concept of pharmaceutical targets [PDF]

, 2007
The biomedical world relies heavily on the definition of pharmaceutical targets as an essential step in the drug design process. It is therefore tempting to apply this model to genetic diseases as well.
Laurent Ségalat, MA Lindsay, RR Brinkman, F Sams-Dood, F Sams-Dood, M Ceccarelli, V Dubowitz, TA Rando, G Meister, C Eggert, P Rustin   +10 more
core   +5 more sources

Drought affects Fe deficiency‐induced responses in a purple durum wheat (Triticum turgidum subsp. durum) genotype

Plant Biology, EarlyView.
Combined Fe deficiency and drought in durum wheat trigger interactive responses: drought suppressed root Fe uptake regardless of Fe availability, and both stresses altered phytosiderophore release, ABA level and Fe transporter gene expression, revealing a trade‐off between water and Fe. Abstract Iron (Fe) is essential for plants and humans, with over 2
G. Quagliata, M. D. G. Molina, G. Mannino, E. Coppa, M. N. Saidi, S. Palombieri, F. Sestili, G. Vigani, S. Astolfi   +8 more
wiley   +1 more source

The special Sm core structure of the U7 snRNP: far-reaching significance of a small nuclear ribonucleoprotein [PDF]

, 2018
.: The polypeptide composition of the U7 small nuclear ribonucleoprotein (snRNP) involved in histone messenger RNA (mRNA) 3′ end formation has recently been elucidated.
Pillai, R., Schümperli, D.
core  

The intriguing case of motor neuron disease: ALS and SMA come closer [PDF]

, 2013
MNDs (motor neuron diseases) form a heterogeneous group of pathologies characterized by the progressive degeneration of motor neurons. More and more genetic factors associated with MND encode proteins that have a function in RNA metabolism, suggesting ...
Achsel, T, Barabino, S, Carrì, MT, Cozzolino, M   +3 more
core   +1 more source

Multifunctionality of annual forage crop mixtures for improved biomass, beef cattle diets, and soil health outcomes

Agrosystems, Geosciences &Environment, Volume 9, Issue 2, June 2026.
Abstract Cover crop mixtures (CCMs) can fit well into various agricultural production systems and have gained popularity among grain and livestock producers, as well as organic and market gardeners across western Canada, due to their potential to enhance forage production and soil health.
Akim Tunde Omokanye, Surendra Bhattarai, Guillermo Hernandez Ramirez, Blasius Azuhnwi, Yamily Zavala, Hayford Gyamfi, Bharat Shrestha   +6 more
wiley   +1 more source