Inflammatory pathogenesis of snake venom metalloproteinase‐induced skin necrosis [PDF]
European Journal of Immunology, 2003 AbstractLocal tissue damage, characterized by edema, hemorrhage and necrosis, is a common consequence of envenoming by many vipers. We have investigated the contribution of inflammatory responses induced by the venom metalloproteinase jararhagin (isolated from Bothrops jararaca venom) in the development of these lesions.
Gavin David, Laing +4 more
openaire +2 more sources
Toxins, 2021 Bites from elapid snakes typically result in neurotoxic symptoms in snakebite victims. Neurotoxins are, therefore, often the focus of research relating to understanding the pathogenesis of elapid bites.
Taline D. Kazandjian +7 more
doaj +1 more source
Angiotensin-degrading serine peptidase: A new chymotrypsin-like activity in the venom of Bothrops jararaca partially blocked by the commercial antivenom [PDF]
, 2012 Snakebite envenomation is considered a highly relevant public health hazard in South America, having an impact in terms of mortality and morbidity.
Carvalho, Daniela Cajado +6 more
core +2 more sources
The venom gland transcriptome of the Desert Massasauga Rattlesnake (): towards an understanding of venom composition among advanced snakes (Superfamily Colubroidea) [PDF]
, 2007 BACKGROUND: Snake venoms are complex mixtures of pharmacologically active proteins and peptides which belong to a small number of superfamilies. Global cataloguing of the venom transcriptome facilitates the identification of new families of toxins as ...
Pahari, Susanta +2 more
core +3 more sources
Venom gland transcriptome analyses of two freshwater stingrays (Myliobatiformes : Potamotrygonidae) from Brazil [PDF]
, 2016 Stingrays commonly cause human envenoming related accidents in populations of the sea, near rivers and lakes. Transcriptomic profiles have been used to elucidate components of animal venom, since they are capable of providing molecular information on the
Alencar, Sérgio Amorim de +9 more
core +2 more sources
Integrated “omics” profiling indicates that miRNAs are modulators of the ontogenetic venom composition shift in the Central American rattlesnake, [PDF]
, 2013 Background Understanding the processes that drive the evolution of snake venom is a topic of great research interest in molecular and evolutionary toxinology. Recent studies suggest that ontogenetic changes in venom composition are genetically controlled
Angulo, Yamileth +10 more
core +2 more sources
Journal of Venomous Animals and Toxins including Tropical Diseases, 2022 Background: Several studies have been published on the characterization of Trimeresurus venoms. However, there is still limited information concerning the venom composition of Trimeresurus species distributed throughout Indonesia, which contributes to ...
Syahfitri Anita +11 more
doaj +1 more source
Anti-inflammatory activity of Blutaparon portulacoides ethanolic extract against the inflammatory reaction induced by Bothrops jararacussu venom and isolated myotoxins BthTX-I and II [PDF]
, 2009 This article reports the anti-inflammatory effect of Blutaparon portulacoides (B. portulacoides), specifically the ethanolic extract of its aerial parts, on the edema formation and leukocyte influx caused by Bothrops jararacussu (B.
BARBOSA, AM +6 more
core +2 more sources
Toxins, 2018 Venom composition varies across snakes from all taxonomic levels and is influenced by the snakes’ age, habitat, diet, and sexual dimorphism. The present study reports the first in-depth investigation of venom composition in male and female Bothrops
Fernanda Gobbi Amorim +5 more
doaj +1 more source
Snakebite: An Exploratory Cost-Effectiveness Analysis of Adjunct Treatment Strategies. [PDF]
, 2018 The cost-effectiveness of the standard of care for snakebite treatment, antivenom, and supportive care has been established in various settings. In this study, based on data from South Indian private health-care providers, we address an additional ...
Bulfone, Tommaso C +5 more
core +2 more sources