Results 61 to 70 of about 51,201 (249)

Evaluating the Performance of De Novo Assembly Methods for Venom-Gland Transcriptomics

Toxins, 2018
Venom-gland transcriptomics is a key tool in the study of the evolution, ecology, function, and pharmacology of animal venoms. In particular, gene-expression variation and coding sequences gained through transcriptomics provide key information for ...
Matthew L. Holding, Mark J. Margres, Andrew J. Mason, Christopher L. Parkinson, Darin R. Rokyta   +4 more
doaj   +1 more source

Pictolysin-III, a Hemorrhagic Type-III Metalloproteinase Isolated from Bothrops pictus (Serpentes: Viperidae) Venom, Reduces Mitochondrial Respiration and Induces Cytokine Secretion in Epithelial and Stromal Cell Lines

Pharmaceutics, 2023
From the venom of the Bothrops pictus snake, an endemic species from Peru, we recently have described toxins that inhibited platelet aggregation and cancer cell migration.
Dan E. Vivas-Ruiz, Paola Rosas, Alex Proleón, Daniel Torrejón, Fanny Lazo, Ana Belén Tenorio-Ricca, Francisco Guajardo, Cristopher Almarza, Víctor Andrades, Jessica Astorga, Daniel Oropesa, Jorge Toledo, María Jesús Vera, Jorge Martínez, Ramiro Araya-Maturana, Karen Dubois-Camacho, Marcela A. Hermoso, Valéria G. Alvarenga, Eladio Flores Sanchez, Armando Yarlequé, Luciana Souza Oliveira, Félix A. Urra   +21 more
doaj   +1 more source

Divergent Specialization of Simple Venom Gene Profiles among Rear-Fanged Snake Genera (Helicops and Leptodeira, Dipsadinae, Colubridae)

Toxins, 2022
Many venomous animals express toxins that show extraordinary levels of variation both within and among species. In snakes, most studies of venom variation focus on front-fanged species in the families Viperidae and Elapidae, even though rear-fanged ...
Peter A. Cerda, Jenna M. Crowe-Riddell, Deise J. P. Gonçalves, Drew A. Larson, Thomas F. Duda, Alison R. Davis Rabosky   +5 more
doaj   +1 more source

Crotalus ruber [PDF]

, 2006
Number of Pages: 17Integrative BiologyGeological ...
Beaman, Kent R., Dugan, Eric A.
core   +1 more source

The effect of a serum containing acetyl hexapeptide‐8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: Ex vivo and clinical studies

International Journal of Cosmetic Science, EarlyView.
The novel serum demonstrates significant anti‐skin aging effects, effectively improving static and dynamic wrinkles and skin texture. Therefore, this formulation holds promise as a safe and effective product in the field of anti‐wrinkle skincare products.
Mingjie Zhu, Xiaofeng He, Zailing Zhu, Stephen Lynch, Hequn Wang, Xiaoyin Zhou, Yidong Tu, Andrew Steel, Kung Chi Hsu, Yueqing Niu, Anna Cho, Mutsue Hashimoto, Xi Yan, Maggie Su, Wenna Wang   +14 more
wiley   +1 more source

Serum-based inhibition of pitviper venom by eastern indigo snakes (Drymarchon couperi)

Biology Open, 2019
When organisms possess chemical defenses, their predators may eventually evolve resistance to their toxins. Eastern indigo snakes (Drymarchon couperi; EIS) prey on pitvipers and are suspected to possess physiological resistance to their venom.
Scott M. Goetz, Sara Piccolomini, Michelle Hoffman, James Bogan, Matthew L. Holding, Mary T. Mendonça, David A. Steen   +6 more
doaj   +1 more source

Snakebite envenoming. [PDF]

, 2017
Snakebite envenoming is a neglected tropical disease that kills >100,000 people and maims >400,000 people every year. Impoverished populations living in the rural tropics are particularly vulnerable; snakebite envenoming perpetuates the cycle of poverty.
Calvete, Juan J, Gutiérrez, José María, Habib, Abdulrazaq G, Harrison, Robert, Warrell, David A, Williams, David J   +5 more
core   +3 more sources

Analysis of snake venom metalloproteinases from Myanmar Russell's viper transcriptome [PDF]

Toxicon, 2018
Snake venom metalloproteinases (SVMPs) are the key enzymes in Russell's viper (RV) venom which target all important components of haemostasis, such as clotting factors, platelets, endothelial cells and basement membrane. The structural diversity of SVMPs contributes to the broad spectrum of biological activities. The aim of the study was to investigate
Khin Than Yee, Sissades Tongsima, Olga Vasieva, Chumpol Ngamphiw, Alisa Wilantho, Mark C. Wilkinson, Poorichya Somparn, Trairak Pisitkun, Ponlapat Rojnuckarin   +8 more
openaire   +2 more sources

Polymeric Nanoparticles for the Diagnosis and Treatment of Snakebite

Macromolecular Chemistry and Physics, Volume 227, Issue 1, 15 January 2026.
Snakebite envenomation affects between 1.8 and 5.5 million people annually, many of whom suffer disabilities or even death. Current antivenoms are composed of plasma‐derived antibodies. However, there remains an underexplored opportunity to utilise polymer‐based nanoparticles.
Neil Prabhakar, Thomas Oliver, Alexander N. Baker   +2 more
wiley   +1 more source

Activation of snake venom metalloproteinases by a cysteine switch‐like mechanism [PDF]

FEBS Letters, 1993
The cDNAs of several snake venom zinc endopeptidases code for a putative propeptide, which includes the conserved cysteine‐containing sequence PKMCGVT. It has been suggested that binding of the cysteine thiol function to the active‐site zinc, resulting in inactivation of the catalytic domain, occurs in a mode similar to the ‘cysteine switch’ mechanism ...
Grams, Frank, Huber, Robert, Kress, Lawrence F., Moroder, Luis, Bode, Wolfram   +4 more
openaire   +2 more sources