Results 31 to 40 of about 41,580 (266)
Heart Views, 2017 Although provisional pacemaker implantation can safely be done in many cases, a rare complication such as knotted electrode has been described, especially when the procedure is performed without fluoroscopy guidance.
Mohsen Mohandes +5 more
doaj +1 more source
Design of an Impedance-Controlled Hot Snare Polypectomy Device
Sensors, 2019 This paper goes through the process of first designing a feedback system that allows for the measuring of impedance while using the hot snare polypectomy method. The electrosurgical unit used in this study was the Olympus PSD-30.
CurtisLee Thornton, JungHun Choi
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Conservation Science and Practice, 2019 Illegal activity within protected areas is a primary driver of species decline and threatens conservation efforts. In the western corridor of the Serengeti Ecosystem of northern Tanzania, the Grumeti and Ikorongo Game Reserves and Ikona Wildlife ...
Kristen Denninger Snyder +2 more
doaj +1 more source
Securing SNAREs for assembly [PDF]
Journal of Biological Chemistry, 2020 SNARE proteins are essential for exocytosis, mediating the fusion of vesicles with their target membrane. Tethering factors play a key role in chaperoning SNARE assembly; however, the underlying molecular mechanisms are not well-understood. Here, Travis et al.
Yongli Zhang, Jie Yang
openaire +2 more sources
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Journal of Plant Interactions, 2019 The defense regulon has been defined genetically in Arabidopsis thaliana to involve the syntaxin PENETRATION1 (PEN1), the secreted glucosidase (PEN2) and an ATP-binding cassette (ABC) transporter (PEN3).
Hannah W. Austin +5 more
doaj +1 more source
Munc18-1-regulated stage-wise SNARE assembly underlying synaptic exocytosis
eLife, 2015 Synaptic-soluble N-ethylmaleimide-sensitive factor attachment receptor (SNARE) proteins couple their stage-wise folding/assembly to rapid exocytosis of neurotransmitters in a Munc18-1-dependent manner.
Lu Ma +6 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2005 SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) are now generally accepted to be the major players in the final stage of the docking and the subsequent fusion of diverse vesicle-mediated transport events. The SNARE-mediated process is conserved evolutionally from yeast to human, as well as mechanistically and ...
openaire +3 more sources