Results 41 to 50 of about 41,393 (265)

Securing SNAREs for assembly [PDF]

Journal of Biological Chemistry, 2020
SNARE proteins are essential for exocytosis, mediating the fusion of vesicles with their target membrane. Tethering factors play a key role in chaperoning SNARE assembly; however, the underlying molecular mechanisms are not well-understood. Here, Travis et al.
Yongli Zhang, Jie Yang
openaire   +2 more sources

Large mammal diversity of Vietnam’s Chu Yang Sin National Park and the first experimental assessment of their vulnerability to snaring

Journal of Threatened Taxa
The Annamite Mountains of Indochina have high mammal endemism but also face a mammalian extinction crisis, primarily from the indiscriminate use of snares.
Minh Thi Anh Nguyen, Thuy Thi Bich Vo, Quy Tan Le, Vy Tran Nguyen, Vu Linh Nguyen, R.J. Timmins, Anthony J. Giordano   +6 more
doaj   +1 more source

Percutaneous retrieval of a knotted provisional pacemaker using proximal electrode cut off and distal end snaring

Heart Views, 2017
Although provisional pacemaker implantation can safely be done in many cases, a rare complication such as knotted electrode has been described, especially when the procedure is performed without fluoroscopy guidance.
Mohsen Mohandes, Natalia Rodríguez, Francisco Fernández, Cristina Moreno, Oscar Palazón, Alfredo Bardaj   +5 more
doaj   +1 more source

Design of an Impedance-Controlled Hot Snare Polypectomy Device

Sensors, 2019
This paper goes through the process of first designing a feedback system that allows for the measuring of impedance while using the hot snare polypectomy method. The electrosurgical unit used in this study was the Olympus PSD-30.
CurtisLee Thornton, JungHun Choi
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Predicting the risk of illegal activity and evaluating law enforcement interventions in the western Serengeti

Conservation Science and Practice, 2019
Illegal activity within protected areas is a primary driver of species decline and threatens conservation efforts. In the western corridor of the Serengeti Ecosystem of northern Tanzania, the Grumeti and Ikorongo Game Reserves and Ikona Wildlife ...
Kristen Denninger Snyder, Philemon B. Mneney, George Wittemyer   +2 more
doaj   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

An expanded role of the SNARE-containing regulon as it relates to the defense process that Glycine max has to Heterodera glycines

Journal of Plant Interactions, 2019
The defense regulon has been defined genetically in Arabidopsis thaliana to involve the syntaxin PENETRATION1 (PEN1), the secreted glucosidase (PEN2) and an ATP-binding cassette (ABC) transporter (PEN3).
Hannah W. Austin, Brant T. McNeece, Keshav Sharma, Prakash M. Niraula, Katherine S. Lawrence, Vincent P. Klink   +5 more
doaj   +1 more source

Munc18-1-regulated stage-wise SNARE assembly underlying synaptic exocytosis

eLife, 2015
Synaptic-soluble N-ethylmaleimide-sensitive factor attachment receptor (SNARE) proteins couple their stage-wise folding/assembly to rapid exocytosis of neurotransmitters in a Munc18-1-dependent manner.
Lu Ma, Aleksander A Rebane, Guangcan Yang, Zhiqun Xi, Yuhao Kang, Ying Gao, Yongli Zhang   +6 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source