Results 61 to 70 of about 41,393 (265)
Journal of Digestive EndoscopyForeign body ingestion is a commonly encountered problem clinically with management targeted at early radiological imaging to identify high-risk features that can increase the risk of perforation. We present a 23-year-old patient with no known medical or
Raghav Bassi +3 more
doaj +1 more source
Percutaneous Salvage of an Impella Pretzel
JACC: Case Reports, 2019 This report describes a case in which bedside manipulation of an Impella CP led to device entanglement in the aorta. Using a snare and counter-traction, we were able to untangle and re-deliver it into the left ventricle to restore normal device support. (
Moses Mathur, MD, MSc +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Identification of SNARE Proteins Through a Novel Hybrid Model
IEEE Access, 2020 SNARE proteins are a large family of membrane fusion proteins. As a lot of human diseases are related to the SNARE proteins, they have attracted people to study them.
Guilin Li
doaj +1 more source
The influence of cell membrane and SNAP25 linker loop on the dynamics and unzipping of SNARE complex. [PDF]
PLoS ONE, 2017 The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex is composed of three neuronal proteins VAMP2, Syntaxin and SNAP25, which plays a core role during the process of membrane fusion.
Yi Shi, Yong Zhang, Jizhong Lou
doaj +1 more source
Endosomal and Phagosomal SNAREs [PDF]
Physiological Reviews, 2018 The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein family is of vital importance for organelle communication. The complexing of cognate SNARE members present in both the donor and target organellar membranes drives the membrane fusion required for intracellular transport.
Ilse Dingjan +5 more
openaire +4 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Toxins, 2019 The detection of catalytically active botulinum neurotoxins (BoNTs) can be achieved by monitoring the enzymatic cleavage of soluble NSF (N-ethylmaleimide-sensitive-factor) attachment protein receptor (SNARE) proteins by the toxins’ light chains (LC)
Laura von Berg +5 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Model of SNARE-mediated membrane adhesion kinetics. [PDF]
PLoS ONE, 2009 SNARE proteins are conserved components of the core fusion machinery driving diverse membrane adhesion and fusion processes in the cell. In many cases micron-sized membranes adhere over large areas before fusion. Reconstituted in vitro assays have helped
Jason M Warner +2 more
doaj +1 more source