Results 11 to 20 of about 73,344 (342)

SNARE Complex-Associated Proteins and Alcohol. [PDF]

open access: yesAlcohol Clin Exp Res, 2020
Alcohol addiction causes major health problems throughout the world, causing numerous deaths and incurring a huge economic burden to society. To develop an intervention for alcohol addiction, it is necessary to identify molecular target(s) of alcohol and associated molecular mechanisms of alcohol action.
Das J.
europepmc   +4 more sources

Fusion Pore Dynamics and Snare Complex Mobility [PDF]

open access: bronzeBiophysical Journal, 2019
Satyan Sharma, Manfred Lindau
openalex   +3 more sources

SNARE Complexity in Arbuscular Mycorrhizal Symbiosis [PDF]

open access: yesFrontiers in Plant Science, 2020
How cells control the proper delivery of vesicles and their associated cargo to specific plasma membrane (PM) domains upon internal or external cues is a major question in plant cell biology. A widely held hypothesis is that expansion of plant exocytotic machinery components, such as SNARE proteins, has led to a diversification of exocytotic membrane ...
Huisman, Rik   +3 more
openaire   +4 more sources

SNARE complex assembly and disassembly [PDF]

open access: yesCurrent Biology, 2018
A fundamental hallmark of eukaryotic cells is their compartmentalization into functionally distinct organelles, including those of the secretory and endocytic pathways. Transport of cargo between these compartments and to/from the cell surface is mediated by membrane-bound vesicles and tubules.
Tae-Young, Yoon, Mary, Munson
openaire   +2 more sources

Action of Complexin on SNARE Complex [PDF]

open access: yesJournal of Biological Chemistry, 2002
Calcium-dependent synaptic vesicle exocytosis requires three SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) proteins: synaptobrevin/vesicle-associated membrane protein in the vesicular membrane and syntaxin and SNAP-25 in the presynaptic membrane.
Kuang, Hu   +3 more
openaire   +2 more sources

Sequential analysis of trans-SNARE formation in intracellular membrane fusion. [PDF]

open access: yesPLoS Biology, 2012
SNARE complexes are required for membrane fusion in the endomembrane system. They contain coiled-coil bundles of four helices, three (Q(a), Q(b), and Q(c)) from target (t)-SNAREs and one (R) from the vesicular (v)-SNARE.
Kannan Alpadi   +7 more
doaj   +1 more source

HOPS recognizes each SNARE, assembling ternary trans-complexes for rapid fusion upon engagement with the 4th SNARE

open access: yeseLife, 2020
Yeast vacuole fusion requires R-SNARE, Q-SNAREs, and HOPS. A HOPS SM-family subunit binds the R- and Qa-SNAREs. We now report that HOPS binds each of the four SNAREs.
Hongki Song   +4 more
doaj   +1 more source

The Sec1/Munc18 protein Vps45 holds the Qa-SNARE Tlg2 in an open conformation

open access: yeseLife, 2020
Fusion of intracellular trafficking vesicles is mediated by the assembly of SNARE proteins into membrane-bridging complexes. SNARE-mediated membrane fusion requires Sec1/Munc18-family (SM) proteins, SNARE chaperones that can function as templates to ...
Travis J Eisemann   +5 more
doaj   +1 more source

The influence of cell membrane and SNAP25 linker loop on the dynamics and unzipping of SNARE complex. [PDF]

open access: yesPLoS ONE, 2017
The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex is composed of three neuronal proteins VAMP2, Syntaxin and SNAP25, which plays a core role during the process of membrane fusion.
Yi Shi, Yong Zhang, Jizhong Lou
doaj   +1 more source

Complex Lipid Requirements for SNARE- and SNARE Chaperone-dependent Membrane Fusion [PDF]

open access: yesJournal of Biological Chemistry, 2009
Membrane fusion without lysis has been reconstituted with purified yeast vacuolar SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors), the SNARE chaperones Sec17p/Sec18p and the multifunctional HOPS complex, which includes a subunit of the SNARE-interactive Sec1-Munc18 family, and vacuolar lipids: phosphatidylcholine (PC ...
Joji, Mima, William, Wickner
openaire   +2 more sources

Home - About - Disclaimer - Privacy