Results 141 to 150 of about 2,855 (178)

Androgen receptor modulatory miR-1271-5p can promote hormone sensitive prostate cancer cell growth. [PDF]

open access: yesFront Oncol
Kalofonou F   +5 more
europepmc   +1 more source

Correlated Overexpression of Metadherin and SND1 in Glioma Cells

Biological Chemistry, 2016
Abstract Glioma is the most common primary brain tumor with poor prognosis. Effective treatment of glioma remains a big challenge due to complex pathogenic mechanisms. Previous studies have shown that metadherin (MTDH) and its interacting protein staphylococcal nuclease domain containing 1 (SND1) are overexpressed in many solid tumors. To elucidate the
Zhangxiu He, Lanlan Wei
exaly   +3 more sources

FXR1 impedes the development of osteoarthritis by targeting SND1

Clinical and Experimental Rheumatology, 2022
To investigate the role of fragile X mental retardation syndrome-related protein 1 (FXR1), an RNA binding protein, in the development of osteoarthritis (OA), to define its mechanism of action in cartilage, and to determine whether targeting FXR1 can prevent OA in mice.Western blot analysis and quantitative polymerase chain reaction were performed using
Hanqi, Wang   +6 more
openaire   +2 more sources

Multifunction Protein Staphylococcal Nuclease Domain Containing 1 (SND1) Promotes Tumor Angiogenesis in Human Hepatocellular Carcinoma Through Novel Pathway That Involves Nuclear Factor κB and miR-221 [PDF]

open access: yesJournal of Biological Chemistry, 2012
Staphylococcal nuclease domain-containing 1 (SND1) is a multifunctional protein that is overexpressed in multiple cancers, including hepatocellular carcinoma (HCC).
Paul B Fisher   +2 more
exaly   +2 more sources

SND1 Expression in Breast Cancer Tumors Is Associated With Poor Prognosis

Annals of the New York Academy of Sciences, 2018
AbstractStaphylococcal nuclease domain‐containing 1 (SND1) expression is crucial for breast cancer metastasis; however, the clinical implications of SND1 expression in breast cancer remain unclear. This study investigated the relationship of SND1 protein expression both with metastasis and the prognoses of 144 breast cancer patients over a 10‐year ...
Lisha Sun, Caigang Liu, Xi Gu
exaly   +3 more sources

Disruption of SND1–MTDH Interaction by a High Affinity Peptide Results in SND1 Degradation and Cytotoxicity to Breast Cancer Cells In Vitro and In Vivo

Molecular Cancer Therapeutics, 2021
Abstract Staphylococcal nuclease domain-containing protein 1 (SND1) is a multifunctional oncoprotein overexpressed in breast cancer. Binding of metadherin (MTDH) to SND1 results in the stabilization of SND1 and is important in the initiation and progression of breast cancer.
Peng Li   +10 more
openaire   +3 more sources

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