Results 161 to 170 of about 2,855 (178)

SND1 Acts Downstream of TGFβ1 and Upstream of Smurf1 to Promote Breast Cancer Metastasis

Cancer Research, 2015
Abstract SND1 is an AEG-1/MTDH/LYRIC-binding protein that is upregulated in numerous human cancers, where it has been assigned multiple functional roles. In this study, we report its association with the TGFβ1 signaling pathway, which promotes epithelial–mesenchymal transition (EMT) in breast cancer.
Lin, Yu, Xin, Liu, Kang, Cui, Yanbo, Di, Lingbiao, Xin, Xiaoming, Sun, Wei, Zhang, Xi, Yang, Minxin, Wei, Zhi, Yao, Jie, Yang   +10 more
openaire   +2 more sources

SND1 Promotes Radioresistance in Cervical Cancer Cells by Targeting the DNA Damage Response

Cancer Biotherapy and Radiopharmaceuticals
Background: Radiotherapy is one of the most effective therapeutic strategies for cervical cancer patients, although radioresistance-mediated residual and recurrent tumors are the main cause of treatment failure. However, the mechanism of tumor radioresistance is still elusive.
Lin Ge, Xiaoming Sun, Jie Yang
exaly   +3 more sources

The Multifunctional Protein, Snd1, Involved in tRNA Splicing of the Fission Yeast

Journal of the Korea Entertainment Industry Association, 2016
By screening a bank of temperature sensitive mutants of Schizosaccharomyces pombe, we had previously isolated six pre-tRNA splicing mutants named ptp1 to ptp6. We cloned the ptp4-2 + gene from a genomic DNA library by complementation of the growth defect.
openaire   +1 more source

Investigating the role of SND1 in Glioblastoma using RNA-Seq

Glioblastoma (GBM) is the most aggressive and lethal form of primary brain tumor, known for its rapid growth and high resistance to conventional therapies. Despite extensive research, the prognosis for GBM patients remains poor, with a median survival time of approximately 12 to 18 months following diagnosis.
Tisha Kalpesh Desai, Srinivas Somarowthu
openaire   +1 more source

PAX5 Activates Telomerase Activity and Proliferation in Keloid Fibroblasts by Transcriptional Regulation of SND1, Thus Promoting Keloid Growth in Burn-Injured Skin

Inflammation Research, 2021
Yong Song
exaly  

LncRNA LINC00665 Promotes Prostate Cancer Progression via miR-1224-5p/SND1 Axis

OncoTargets and Therapy, 2020
Zhixian Yu, Weiping Huang
exaly  

The Novel Chromatin Architectural Regulator SND1 Promotes Glioma Proliferation and Invasion and Predicts the Prognosis of Patients

Neuro-Oncology, 2019
Dan Hua, Lin Yu, Xiu-Wu Bian
exaly  

A Pan-Cancer Analysis of the Oncogenic Role of Staphylococcal Nuclease Domain-Containing Protein 1 (SND1) in Human Tumors

Genomics, 2020
Nan Zhang, Xinxin Zhang, Xingjie Gao
exaly  

SND1 Acts as an Anti-Apoptotic Factor via Regulating the Expression of lncRNA UCA1 in Hepatocellular Carcinoma

RNA Biology, 2018
Zhi Yao, Xingjie Gao, Jie Yang
exaly  

Suppression of miR-184 in Malignant Gliomas Upregulates SND1 and Promotes Tumor Aggressiveness.

Neuro-Oncology, 2015
Paul B Fisher, Mohammad A Alzubi, Devanand Sarkar   +2 more
exaly