Results 51 to 60 of about 2,855 (178)

Exploring binding modes of the selected inhibitors to SND1 by all-atom molecular dynamics simulations

, 2023
Breast cancer is the leading cause of cancer-related deaths in women. Previous studies have indicated that disrupting the interaction between Metadherin (MTDH) and Staphylococcal nuclease domain containing 1 (SND1) can inhibit breast cancer development ...
Senchen Liu (16417045), Peilin Pang (16417042), Yanjun Zhang (168997), Dongqiang Miao (16417054), Shuyue Gong (16417051), Xiafei Hao (16417048), Yuxin Tian (442502)   +6 more
core   +1 more source

Circ SMARCA5 Inhibited Tumor Metastasis by Interacting with SND1 and Downregulating the YWHAB Gene in Cervical Cancer

Cell Transplantation, 2021
Cervical cancer is one of the diseases that seriously endanger women’s health. Circular RNA plays an important role in regulating the occurrence and development of cervical cancer.
Xia Zhang, Qing Zhang, Ke Zhang, Fang Wang, Xiaogai Qiao, Jinquan Cui   +5 more
doaj   +1 more source

A Study of The Snd1/Prmt5 Axis In Liver Cancer By Genetic Mouse Models [PDF]

, 2023
Arginine methylation is an essential post-translational modification (PTM) in cells. Protein arginine methyltransferase 5 (PRMT5) is the primary enzyme that catalyzes symmetric dimethyl arginine (SDMA) and requires methylosome protein 50 (MEP50) for ...
Wright, Tanner
core   +1 more source

Cheminformatics and biomolecular dynamics studies towards the discovery of anti-staphylococcal nuclease domain-containing 1 (SND1) inhibitors to treat metastatic breast cancer

Saudi Pharmaceutical Journal, 2023
Metastatic breast cancer is a prime health concern and leading health burden across the globe. Previous efforts have shown that protein–protein interaction between Metadherin and Staphylococcal nuclease domaincontaining 1 (SND1) promotes initiation of ...
Nahlah Makki Almansour
doaj   +1 more source

Linc00668 Promotes Invasion and Stem Cell-Like Properties of Breast Cancer Cells by Interaction With SND1

Frontiers in Oncology, 2020
Long non-coding RNAs (lncRNAs) are reported to be involved in breast cancer progression. Herein, we observed that the expression of Linc00668 was increased in breast cancer compared to normal tissue.
Wenchang Qian, Yong Zhu, Mingming Wu, Qianying Guo, Zhengsheng Wu, Peter E. Lobie, Peter E. Lobie, Tao Zhu, Tao Zhu   +8 more
doaj   +1 more source

Ectopic Expression of Hawthorn SND1 Gene in Tobacco

International Journal of Environmental and Agriculture Research, 2017
NAC proteins are plant-specific transcription factors (TFs) and have been shown to function in plant development processes and abiotic and/or biotic stress responses. SECONDARY WALL-ASSOCIATED NAC DOMAIN PROTEIN1 (SND1) is one type of NAC TFs, which is a key regulator in the regulation network for secondary wall synthesis. In this study, the SND1 gene,
Guofen Han, Hongyan Dai
openaire   +1 more source

SPT6 recruits SND1 to co‐activate human telomerase reverse transcriptase to promote colon cancer progression

Molecular Oncology, 2021
Human telomerase reverse transcriptase (hTERT) plays an extremely important role in cancer initiation and development, including colorectal cancer (CRC). However, the precise upstream regulatory mechanisms of hTERT in different cancer types remain poorly
Chaoliang Diao, Ping Guo, Wenjing Yang, Yao Sun, Yina Liao, Yue Yan, Anshi Zhao, Xin Cai, Jiaojiao Hao, Sheng Hu, Wendan Yu, Manyu Chen, Ruozhu Wang, Wenyang Li, Yan Zuo, Jinjin Pan, Chunyu Hua, Xiaona Lu, Wenhua Fan, Zongheng Zheng, Wuguo Deng, Guangyu Luo, Wei Guo   +22 more
doaj   +1 more source

Posttranscriptional Inhibition of Protein Tyrosine Phosphatase Nonreceptor Type 23 by Staphylococcal Nuclease and Tudor Domain Containing 1: Implications for Hepatocellular Carcinoma

Hepatology Communications, 2019
Oncoprotein staphylococcal nuclease and tudor domain containing 1 (SND1) regulates gene expression at a posttranscriptional level in multiple cancers, including hepatocellular carcinoma (HCC).
Nidhi Jariwala, Rachel G. Mendoza, Dawn Garcia, Zhao Lai, Mark A. Subler, Jolene J. Windle, Nitai D. Mukhopadhyay, Paul B. Fisher, Yidong Chen, Devanand Sarkar   +9 more
doaj   +1 more source

Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m6A-dependent recognition of Nrf2 mRNA mediated by SND1

Journal of Experimental & Clinical Cancer Research, 2023
Background Ferroptosis has been linked to tumor progression and resistance to antineoplastic therapy. Long noncoding RNA (lncRNA) exerts a regulatory role in various biological processes of tumor cells, while the function and molecular mechanism of ...
Jianglin Zheng, Qing Zhang, Zhen Zhao, Yue Qiu, Yujie Zhou, Zhipeng Wu, Cheng Jiang, Xuan Wang, Xiaobing Jiang   +8 more
doaj   +1 more source

ZNF143 inhibits hepatocyte mitophagy and promotes non-alcoholic fatty liver disease by targeting increased lncRNA NEAT1 expression to activate ROCK2 pathway

Epigenetics, 2023
Background: Nonalcoholic fatty liver disease (NAFLD) is the most common hepatic disorders worldwide. The mitophagy is suggested to be repressed in NAFLD, but the mechanism remains to be elucidated. Methods: NAFLD cell and mouse models were established by
Yujie Dong, Minjie Hu, Kewei Tan, Rongjuan Dai   +3 more
doaj   +1 more source