Results 1 to 10 of about 3,185 (186)

Development of black cumin seed oil (Nigella sativa L.) SNEDDS into solid-SNEDDS and its characterization [PDF]

Pharmaciana, 2021
Black cumin seed oil (MBJH) (Nigella sativa L.) is a well-known herb with pharmacology activities such as anticancer and anti-thrombocytopenia. The limitation of MBJH has poor absorption when using oral dosage form.
Rodhia Ulfa, Dwi Utami, Iis Wahyuningsih
doaj   +3 more sources

An in Vitro Study on Anticancer Efficacy of Capecitabine- and Vorinostat-incorporated Self-nanoemulsions [PDF]

Journal of Biomedical Physics and Engineering
Background: Cancer has emerged as a critical global health concern due to its widespread prevalence and impact on individuals, families, communities, and healthcare systems worldwide.Objective: We investigated the anticancer effectiveness of capecitabine
Razieh Nazari-Vanani, Naghmeh Sattarahmady, Khashayar Karimian, Hossein Heli   +3 more
doaj   +2 more sources

A Hyaluronic Acid Functionalized Self-Nano-Emulsifying Drug Delivery System (SNEDDS) for Enhancement in Ciprofloxacin Targeted Delivery against Intracellular Infection [PDF]

Nanomaterials, 2021
Ciprofloxacin (CIP), a potent anti-bacterial agent of the fluroquinolone family, shows poor solubility and permeability, thus leading to the development of intracellular pathogens induced multi-drug resistance and biofilms formation.
Rabia Arshad, Tanveer A. Tabish, Maria Hassan Kiani, Ibrahim M. Ibrahim, Gul Shahnaz, Abbas Rahdar, Misook Kang, Sadanand Pandey   +7 more
doaj   +3 more sources

Fabrication and evaluation of solidified nanoemulsion designs for systemic delivery of atorvastatin through the lung [PDF]

Scientific Reports
To improve the solubility of atorvastatin and overcome the stability issues of liquid nanoemulsion, the current study aimed to synthesize solidified SNEDDS particles with aerodynamic diameter of ≤ 3 μm.
Muhammad Danish Saeed, Kifayat Ullah Shah, Asif Nawaz, Faiqa Falak Naz, Amira Metouekel, Gamal A. Shazly, Musaab Dauelbait   +6 more
doaj   +2 more sources

Development of Alectinib-Suspended SNEDDS for Enhanced Solubility and Dissolution

Pharmaceutics, 2022
Alectinib hydrochloride (ALH), a tyrosine kinase inhibitor, is a practically water-insoluble drug classified as BCS class IV. The present study aimed to develop novel suspended self-nanoemulsifying drug delivery system (Su-SNEDDS) to enhance the ...
Eun Ji Park, Seung Ah Choi, Kyoung Ah Min, Jun-Pil Jee, Sung Giu Jin, Kwan Hyung Cho   +5 more
doaj   +3 more sources

Assessment of Self-Nanoemulsifying Drug Delivery System (SNEDDS) of Ethyl Acetate Fraction from Mangosteen (Garcinia mangostana L.,) Peels to Eschericia coli, Pseudomonas aeroginosa, and Proteus mirabilis [PDF]

Majalah Obat Tradisional, 2019
Mangosteen peels have antibacterial activity. SNEDDS has many advantages in developing a drug delivery system to increase the penetration of active compounds. The purpose of this study was to compare the effectiveness of the antibacterial SNEDDS of ethyl
Liza Pratiwi
doaj   +3 more sources

Formulation and Evaluation of Solid Self-Nanoemulsifying Drug Delivery System of Cannabidiol for Enhanced Solubility and Bioavailability [PDF]

Pharmaceutics
Background/Objectives: This study aims to develop a solid self-nanoemulsifying drug delivery system (SNEDDS) to enhance the solubility and oral bioavailability of cannabidiol (CBD).
Fengying Wu, Qing Ma, Guanghui Tian, Kaixian Chen, Rulei Yang, Jingshan Shen   +5 more
doaj   +2 more sources

Characterization of SNEDDS Formulated with Single Bulb Garlic and its Anti-Inflammatory Effect on 3T3-L1 [PDF]

Hayati Journal of Biosciences
Inflammation is an early symptom of a disease that reduces the level of health. Single-bulb garlic (Allium sativum L.) is used medicinally as a plant with a broad pharmacological effect, especially anti-inflammatory activity.
Sri Rahayu Lestari, Sunaryono Sunaryono, Hendra Susanto, Hidajah Rachmawati , Rony Irawanto, Dewi Sekar Miasih, Alif Rosyidah El Baroroh, Yuslinda Annisa, Muhammad Sasmito Djati   +8 more
doaj   +3 more sources

Preparation of Solid Self-Nanoemulsifying Drug Delivery Systems (S-SNEDDS) by Co-Extrusion of Liquid SNEDDS and Polymeric Carriers—A New and Promising Formulation Approach to Improve the Solubility of Poorly Water-Soluble Drugs

Pharmaceuticals, 2022
The present study focused on a new formulation approach to improving the solubility of drugs with poor aqueous solubility. A hot melt extrusion (HME) process was applied to prepare drug-loaded solid self-nanoemulsifying drug delivery systems (S-SNEDDS ...
Fabian-Pascal Schmied, Alexander Bernhardt, Sandra Klein   +2 more
doaj   +1 more source

Profil Ketoksikan Akut SNEDDS Propolis

Jurnal Sains Farmasi & Klinis, 2022
Propolis memiliki efek imunostimulan yang tinggi namun tidak larut air dan memiliki bioavailabilitas yang rendah. Formulasi propolis dalam bentuk SNEDDS terbukti mampu meningkatkan aktivitas imunostimulannya, namun juga memberikan potensi ketoksikan dikarenakan kecilnya ukuran partikel nano dan akumulasi nya di dalam tubuh.
Arba Pramundita Ramadani, Yandi Syukri, Sherina Nabila Putri Hakim, Annisa Fitria   +3 more
openaire   +1 more source