Results 21 to 30 of about 3,236 (202)
Open Chemistry, 2021 This study aimed to identify the effectiveness of SNEDDS of Pegagan Leaf Ethanol Extract (PLE) to reduce fasting blood glucose (FBG) levels in zebrafish. Centella asiatica (L.) Urb.
Hayati Farida +3 more
doaj +1 more source
Self-nanoemulsifying drug delivery systems (SNEDDS) for oral delivery of Garcinia kola seeds ethanolic extract: formulation and in vivo antimalarial activity. [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2020 Context: Garcinia kola seeds are widely used in Congolese traditional medicine to treat uncomplicated malaria. While the ethanolic extract of these seeds (GK) is reputed for oral antimalarial activity, some of its constituents have shown poor water ...
Grady K. Mukubwa +5 more
doaj
Nanoformulations as a strategy to overcome the delivery limitations of cannabinoids
Phytotherapy Research, Volume 37, Issue 4, Page 1526-1538, April 2023., 2023 Abstract Medical cannabis has received significant interest in recent years due to its promising benefits in the management of pain, anxiety, depression and neurological and movement disorders. Specifically, the major phytocannabinoids derived from the cannabis plant such as (−) trans‐Δ9‐tetrahydrocannabinol (THC) and cannabidiol (CBD), have been shown
T. Srinivasa Reddy +2 more
wiley +1 more source
Validated spectrofluorometric method for determination of gemfibrozil in self nanoemulsifying drug delivery systems (SNEDDS) [PDF]
, 2015 A spectrofluorometric method has been developed and validated for the determination of gemfibrozil. The method is based on the excitation and emission capacities of gemfibrozil with excitation and emission wavelengths of 276 and 304 nm respectively. This
Aróztegui Trenchs, Montserrat +4 more
core +2 more sources
In vitro Naringenin SNEDDS Release Test by Dissolution
Natural Sciences Engineering and Technology Journal, 2022 Naringenin is the main flavanone in grapefruit which has anti-inflammatory, anti-cancer, hepatoprotective and antilipid peroxidation effects. Its low solubility in water causes dissolution and low bioavailability when taken orally. This study aims to increase the solubility and bioavailability of naringenin by using the SNEDDS technique.
Gendis Purno Yudanti +2 more
openaire +1 more source
Recent advances in targeted antibacterial therapy basing on nanomaterials
Exploration, Volume 3, Issue 1, February 2023., 2023 To address the challenge of antibiotic‐resistant bacteria, nanomaterials‐mediated targeted bacteria depletion in either a passive or active manner has emerged as one of the most promising approaches for antibacterial treatment. In this review, we summarize the recent development in the field of targeted antibacterial therapy based on nanomaterials ...
Zhongmin Geng, Zhenping Cao, Jinyao Liu
wiley +1 more source
Asian Journal of Pharmaceutical Sciences, 2019 Self-nanoemulsifying drug delivery system (SNEDDS) has emerged as a promising platform to improve oral absorption of drugs with poor solubility and low permeability. However, large polarity molecules with insufficient lipid solubility, such as paclitaxel
Dawei Ding +8 more
doaj +1 more source
The safety and efficacy of low oral doses of cannabidiol: An evaluation of the evidence
Clinical and Translational Science, Volume 16, Issue 1, Page 10-30, January 2023., 2023 Abstract Global interest in the non‐intoxicating cannabis constituent, cannabidiol (CBD), is increasing with claims of therapeutic effects across a diversity of health conditions. At present, there is sufficient clinical trial evidence to support the use of high oral doses of CBD (e.g., 10–50 mg/kg) in treating intractable childhood epilepsies. However,
Jonathon C. Arnold +3 more
wiley +1 more source
Formulation self nano emulsifying drug delivery system glimepiride using oleic acid as oil phase [PDF]
Pharmaciana, 2017 Glimepiride is a third generation sulphonylurea antidiabetic drug. Glimepiride is poorly water soluble drug that may cause poor dissolution and unpredicted bioavailability.
Sani Ega Priani +2 more
doaj +1 more source
Acta Pharmaceutica Sinica B, 2019 This study assessed the influence of the composition of drug-free SNEDDS co-dosed with aqueous suspensions of carvedilol (CAR), cinnarizine (CIN) or R3040 on drug solubilization in a two-compartment in vitro lipolysis model.
ScheylaDaniela Siqueira Jørgensen +4 more
doaj +1 more source