Results 31 to 40 of about 3,204 (201)

Exploring the utility of the Chasing Principle: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension

open access: yesActa Pharmaceutica Sinica B, 2019
This study assessed the influence of the composition of drug-free SNEDDS co-dosed with aqueous suspensions of carvedilol (CAR), cinnarizine (CIN) or R3040 on drug solubilization in a two-compartment in vitro lipolysis model.
ScheylaDaniela Siqueira Jørgensen   +4 more
doaj   +1 more source

Formulation self nano emulsifying drug delivery system glimepiride using oleic acid as oil phase [PDF]

open access: yesPharmaciana, 2017
Glimepiride is a third generation sulphonylurea antidiabetic drug. Glimepiride is poorly water soluble drug that may cause poor dissolution and unpredicted bioavailability.
Sani Ega Priani   +2 more
doaj   +1 more source

Design and optimization of Eleutherine palmifolia extract-loaded SNEDDS using HLB approach [PDF]

open access: yesJournal of Research in Pharmacy, 2020
The novel surfactant system was designed to formulation a self-nanoemulsifying drug delivery system (SNEDDS) based on Hydrophilic Lipophilic Balance (HLB) value. This study aimed to prepare and characterize the Eleutherine palmifolia (E. palmifolia) extract-loaded self-nanoemulsifying drug delivery system (SNEDDS) using a Hydrophilic Lipophilic Balance
Annisa, Rahmi   +2 more
openaire   +2 more sources

Antibacterial Activity of Self-Nanoemulsifying Drug Delivery System (SNEDDSS) Loaded with Mangosteen (Garcinia mangostana L.,) Peels against Baccilus subtitis, Bacillus cereus, and Staphylococcus aureus isolated from Diabetic Foot Ulcer Patients

open access: yesMajalah Obat Tradisional, 2021
Diabetic Foot Ulcer is a complication of diabetes mellitus characterized by open sores on the surface of the skin or mucous membranes as well as extensive dead tissue followed by bacterial invasion. Patients with Diabetic Foot Ulcer are resistant to some
Liza Pratiwi
doaj   +1 more source

The effect of surfactant on the solubility of kencur (Kaempferia galanga L.) rhizome ethanol extract in self nanoemulsifying drug delivery system [PDF]

open access: yesPharmaciana, 2022
Kencur (Kaempferia galanga L.) rhizome ethanol extract contains a lipophilic compound of ethyl p-methoxycinnamate. Self-nanoemulsifying drug delivery system (SNEDDS) formulation can increase the solubility of the extract in water.
Beti Pudyastuti, Triyadi Hendra Wijaya
doaj   +1 more source

Hepatoprotective Effects of Bioflavonoid Luteolin Using Self-Nanoemulsifying Drug Delivery System

open access: yesMolecules, 2021
Luteolin (LUT) is a natural pharmaceutical compound that is weakly water soluble and has low bioavailability when taken orally. As a result, the goal of this research was to create self-nanoemulsifying drug delivery systems (SNEDDS) for LUT in an attempt
Faiyaz Shakeel   +8 more
doaj   +1 more source

UJI KARAKTERISTIK FISIKO KIMIA DAN STABILITAS MINYAK BIJI JINTAN HITAM DAN JAHE GAJAH DALAM SEDIAAN SNEDDS [PDF]

open access: yes, 2023
Background: Herbal plants are plants with active substances that can intervene in physiological and pathological functions to prevent or cure disease.
PURWANTO, AMARA FEBRIYANTI PUTRI
core  

Solid Self-Nano Emulsifying Nanoplatform Loaded with Tamoxifen and Resveratrol for Treatment of Breast Cancer

open access: yesPharmaceutics, 2022
The solid self-nanoemulsifying drug delivery system (s-SNEDDS) is a growing platform for the delivery of drugs via oral route. In the present work, tamoxifen (TAM) was loaded in SNEDDS with resveratrol (RES), which is a potent chemotherapeutic ...
Nupur Shrivastava   +8 more
doaj   +1 more source

Biopharmaceutical classification of poorly soluble drugs with respect to “enabling formulations” [PDF]

open access: yes, 2013
The large number of drug candidates with poor dissolution characteristics seen in the past decade, has fostered interest in so-called "enabling formulations", i.e., formulations which shall make such drugs bio-available.
Brandl, Martin   +3 more
core   +1 more source

Physical and Chemical Stability Test of SNEDDS (Self-nanoemulsifying Drug Delivery System) and Nanoemulsion Ethyl Acetate Fraction of Garcinia mangostana L.

open access: yesMajalah Obat Tradisional, 2018
The mangosteen peels (Garcinia mangostana L.) has high free radical scavengers activity. This study aims to determine the physical and chemical conditions that are formulated in SNEDDS and nanoemulsion preparations.
Liza Pratiwi   +3 more
doaj   +1 more source

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