Enhancement of bioavailability of herbal drugs for treating viral therapy using SNEDDS as the delivery system [PDF]
SNEDDS were developed with the objective of treating low bioavailability of drugs for antiviral drugs due to its low solubility. The scientist has increased their interest in improving bioavailability and absorption of poorly-water soluble drugs using ...
Rajput Rakesh +5 more
doaj +1 more source
FORMULATION AND EVALUATION OF SOLID-SUPERSATURABLE-SNEDDS OF IBRUTINIB
Objective: The aim of current research is to develop a solid supersaturable self-nanoemulsifying drug delivery system (S-SNEDDS) of ibrutinib for enhancing the solubility and Bioavailability. Methods: Crossential O 94–Croduret 40SS–carbitol are chosen based on the maximum solubility of ibrutinib and were used to construct ternary phase diagrams with ...
K. NAVANEETHA, V. V. BASAVA RAO
openaire +1 more source
Citral is an active compound naturally found in lemongrass, lemon, and lime. Although this pale-yellow liquid confers low water solubility, the compound has been reported to possess good therapeutic features including antiproliferative and anticancer ...
Mira Nadiah Mohd Izham +8 more
doaj +1 more source
Developing health service delivery in a poor and marginalised community in North West Pakistan [PDF]
Objective: To improve maternal health and reduce child mortality through developing health service delivery in a poor and marginalised community in North West Pakistan.
Bingley, Helen +5 more
core +1 more source
Optimization of Thymoquinone-Loaded Self-Nanoemulsion for Management of Indomethacin-Induced Ulcer
To improve the water solubility of thymoquinone (TQ), a major constituent of Nigella sativa seed oil, a TQ-loaded self-nanoemulsifying drug delivery system (SNEDDS) was prepared. The SNEDDS formulation was optimized using almond oil (AO) (Oil; X1), tween
Mohamed F. Radwan +5 more
doaj +1 more source
Development and Evaluation of a Solid Self-Nanoemulsifying Drug Delivery System for Loratadin by Extrusion-Spheronization [PDF]
Purpose: Recently the liquid nanoemulsifying drug delivery systems (SNEDDS) have shown dramatic effects on improving oral bioavailability of poorly soluble drugs.
Mohammadreza Abbaspour +2 more
doaj +1 more source
Quercetin as an Emerging Anti-Melanoma Agent: A Four-Focus Area Therapeutic Development Strategy [PDF]
Replacing current refractory treatments for melanoma with new prevention and therapeutic approaches is crucial in order to successfully treat this aggressive cancer form. Melanoma develops from neural crest cells, which express tyrosinase -- a key enzyme
Gisele Morais Branco +4 more
core +3 more sources
Background: The choice of lipid excipients and their origin are crucial determinant factors in the design of self-nanoemulsifying drug delivery system (SNEDDS).Aim: To investigate the aspects of alternative excipients which can influence the development ...
Aws Alshamsan +4 more
doaj +1 more source
Optimasi Formula Self-Nanoemulsifying Drug Delivery System (SNEDDS) Etil-p-metoksisinamat (EPMS)
Penelitian ini bertujuan untuk menentukan formula Self-Nanoemulsifying Drug Delivery System (SNEDDS) menggunakan zat aktif etil-p-metoksisinamat (EPMS).
Nur Amalia Choironi +5 more
doaj +1 more source
Enhancement of Icariin Aphrodisiac Effect by Solid-SNEDDS Method Using Shark Liver Oil Phase [PDF]
The Epimedium brevicornu Maxim plant contains icariin, a flavonoid compound known for its aphrodisiac effects. However, icariin has low solubility and bioavailability. This study aims to find the best formula for S-SNEDDS icariin, its physical properties,
Indratmoko, Septiana +2 more
core +2 more sources

