Results 41 to 50 of about 3,204 (201)

Brain Targeting Potential of Intravenous Carbamazepine SNEDDS

Journal of Molecular Pharmaceutics & Organic Process Research, 2017
Purpose: The objective of this study was to evaluate the ability of nano-droplets of Self Nano Emulsifying Drug Delivery System to diffuse into the brain tissue. Methods: The preconcentrate was prepared by dissolving oils, surfactants and cosolvents in 1:1 mixture of methanol and chloroform and flash evaporated at 50°C and was stored at room ...
Gannu Praveen Kumar, Rambhau D, Apte SS
openaire   +1 more source

Enhancement of bioavailability of herbal drugs for treating viral therapy using SNEDDS as the delivery system [PDF]

BIO Web of Conferences
SNEDDS were developed with the objective of treating low bioavailability of drugs for antiviral drugs due to its low solubility. The scientist has increased their interest in improving bioavailability and absorption of poorly-water soluble drugs using ...
Rajput Rakesh, Kaur Simranjot, Ingole Yogiraj, Kumar Pandey Narendra, Wilson Kashish, Padhi Swarupanjali   +5 more
doaj   +1 more source

Methods to determine the interactions of micro- and nanoparticles with mucus [PDF]

, 2015
The present review provides an overview of methods and techniques for studying interactions of micro- and nanoparticulate drug delivery system with mucus.
Adebisi, Albrecht, Andreas Bernkop-Schnürch, Apgar, Barthelmes, Beatrice Cattoz, Bhat, Boegh, Bonner, Carlstedt, Chayed, Clausen, Cone, Corfield, Crater, Dawson, Dawson, de Campos, Dünnhaupt, Ensign, Fatin-Rouge, Florence, Florey, Friedl, Gargano, Georgiades, Georgiades, Griffiths, Groo, Groo, Gruber, Hutton, Irene Pereira de Sousa, Jeffrey Pearson, Jin, Julia Grießinger, Khanvilkar, Kirch, Laffleur, Lafitte, Lafitte, Lafitte, Lai, Lai, Lai, Lai, Lamprecht, Larhed, Li, Li, Li, Lieleg, Macierzanka, Macierzanka, Mark Gumbleton, Martin, Marx, Matthew Wilcox, Molino, Muthanna Abdulkarim, Müller, Müller, Nafee, Nordgard, Norris, Peter Griffiths, Ponchel, Primard, Rodahl, Rossi, Round, Salvador Borrós i Gómez, Sarah Dünnhaupt, Saxton, Schuster, Sejin Oh, Silva, Suh, Suh, Suk, Suk, Suk, Takeuchi, Takeuchi, Tirosh, Valentine, Veronese, Waigh, Wang, Wiecinski, Wiedmann, Yoncheva, Yuan   +92 more
core   +2 more sources

FORMULATION AND EVALUATION OF SOLID-SUPERSATURABLE-SNEDDS OF IBRUTINIB

International Journal of Applied Pharmaceutics, 2022
Objective: The aim of current research is to develop a solid supersaturable self-nanoemulsifying drug delivery system (S-SNEDDS) of ibrutinib for enhancing the solubility and Bioavailability. Methods: Crossential O 94–Croduret 40SS–carbitol are chosen based on the maximum solubility of ibrutinib and were used to construct ternary phase diagrams with ...
K. NAVANEETHA, V. V. BASAVA RAO
openaire   +1 more source

Developing health service delivery in a poor and marginalised community in North West Pakistan [PDF]

, 2018
Objective: To improve maternal health and reduce child mortality through developing health service delivery in a poor and marginalised community in North West Pakistan.
Bingley, Helen, Lowe, Nicola M, Medhi, Rashid, Ohly, Heather, Ul Haq, Zia, Zaman, Mukhtiar   +5 more
core   +1 more source

Preparation and Characterization of Self Nano-Emulsifying Drug Delivery System Loaded with Citraland Its Antiproliferative Effect on Colorectal Cells In Vitro

Nanomaterials, 2019
Citral is an active compound naturally found in lemongrass, lemon, and lime. Although this pale-yellow liquid confers low water solubility, the compound has been reported to possess good therapeutic features including antiproliferative and anticancer ...
Mira Nadiah Mohd Izham, Yazmin Hussin, Muhammad Nazirul Mubin Aziz, Swee Keong Yeap, Heshu Sulaiman Rahman, Mas Jaffri Masarudin, Nurul Elyani Mohamad, Rasedee Abdullah, Noorjahan Banu Alitheen   +8 more
doaj   +1 more source

Optimization of Thymoquinone-Loaded Self-Nanoemulsion for Management of Indomethacin-Induced Ulcer

Dose-Response, 2021
To improve the water solubility of thymoquinone (TQ), a major constituent of Nigella sativa seed oil, a TQ-loaded self-nanoemulsifying drug delivery system (SNEDDS) was prepared. The SNEDDS formulation was optimized using almond oil (AO) (Oil; X1), tween
Mohamed F. Radwan, Mohamed A. El-Moselhy, Walied M. Alarif, Mohamed Orif, Nabil K. Alruwaili, Nabil A. Alhakamy   +5 more
doaj   +1 more source

Quercetin as an Emerging Anti-Melanoma Agent: A Four-Focus Area Therapeutic Development Strategy [PDF]

, 2016
Replacing current refractory treatments for melanoma with new prevention and therapeutic approaches is crucial in order to successfully treat this aggressive cancer form. Melanoma develops from neural crest cells, which express tyrosinase -- a key enzyme
Gisele Morais Branco, Kirsten H. Limesand, Micah G. Donovan, Randy Burd, Zoey Harris   +4 more
core   +3 more sources

Development and Evaluation of a Solid Self-Nanoemulsifying Drug Delivery System for Loratadin by Extrusion-Spheronization [PDF]

Advanced Pharmaceutical Bulletin, 2014
Purpose: Recently the liquid nanoemulsifying drug delivery systems (SNEDDS) have shown dramatic effects on improving oral bioavailability of poorly soluble drugs.
Mohammadreza Abbaspour, Negar Jalayer, Behzad Sharif Makhmalzadeh   +2 more
doaj   +1 more source

Role of Alternative Lipid Excipients in the Design of Self-Nanoemulsifying Formulations for Fenofibrate: Characterization, in vitro Dispersion, Digestion and ex vivo Gut Permeation Studies

Frontiers in Pharmacology, 2018
Background: The choice of lipid excipients and their origin are crucial determinant factors in the design of self-nanoemulsifying drug delivery system (SNEDDS).Aim: To investigate the aspects of alternative excipients which can influence the development ...
Aws Alshamsan, Aws Alshamsan, Mohsin Kazi, Mohamed M. Badran, Fars Kaed Alanazi   +4 more
doaj   +1 more source