Results 71 to 80 of about 3,204 (201)

Innovative Self Nano‐Emulsifying Drug Delivery Systems for Peptic Ulcer Therapy: A Review

Particle &Particle Systems Characterization, Volume 42, Issue 1, January 2025.
SNEDDS improve bioavailability and solubility of poorly water‐soluble drugs, aiding in peptic ulcer treatment and regenerative healing. This innovative drug delivery bypasses side effects of conventional forms, utilizing biocompatible macromolecules to enhance solubility and promote healing. SNEDDS‐based systems show promise in boosting drug solubility
Syed Hassan Mujtaba, Rabia Arshad, Waqar Aman, Kashif Barkat, Abdul Malik, Anam Fatima, Salman Arshad Khan, Haleema Sadia, Gul e Maryam, Zeinab Moafian, Abbas Rahdar, M. Ali Aboudzadeh   +11 more
wiley   +1 more source

Development of Guar Gum-Pectin-Based Colon Targeted Solid Self-Nanoemulsifying Drug Delivery System of Xanthohumol

Pharmaceutics, 2022
Present study deciphers development of oral polysaccharide-based colon targeted solid self-nanoemulsifying drug delivery system (S-SNEDDS) of xanthohumol (XH).
Mahesh Hanmantrao, Sourabh Chaterjee, Rajan Kumar, Sukriti Vishwas, Vancha Harish, Omji Porwal, Mohammed Alrouji, Othman Alomeir, Sharif Alhajlah, Monica Gulati, Gaurav Gupta, Kamal Dua, Sachin Kumar Singh   +12 more
doaj   +1 more source

Validation for the Quantification of Andrographolide Isolated From Andrographis Paniculata Nees Plant Using HPLC [PDF]

, 2015
The aim of study was to develop quantitative analysis of isolated andrographolide from Andrographis paniculata and different solvent for prelimenary studies to preperation Self Nano Emulsifying Drug Delivery System (SNEDDS) using HPLC. The separation was
Lukitaningsih, E. (Endang), Martien, R. (Ronny), Nugroho, A. E. (Agung), Syukri, Y. (Yandi)   +3 more
core   +1 more source

Development, physical-chemical stability and release studies of four alcohol-free spironolactone suspensions for use in pediatrics [PDF]

, 2014
Dissolution studies have become of great significance because, in most cases, drug dissolution is the rate-limiting step in the absorption process. As occurs with solid oral dosage forms, heterogeneous disperse systems (suspensions) could also have some ...
Calpena Campmany, Ana Cristina, Clares Naveros, Beatriz, Mallandrich Miret, Mireia, Provenza Bernal, Nora, Ruiz Martínez, Mª Adolfina   +4 more
core   +2 more sources

QbD‐Based Development of Self‐Nanoemulsifying Drug Delivery System for Codelivery of Simvastatin and Ezetimibe With Enhanced In Vitro Dissolution

Journal of Nanotechnology, Volume 2025, Issue 1, 2025.
Simvastatin and ezetimibe are antihyperlipidemic agents that exhibit synergistic therapeutic effects but have poor aqueous solubility, resulting in low and variable oral bioavailability. This study aimed to develop an optimized self‐nanoemulsifying drug delivery system (SNEDDS) for the codelivery of simvastatin and ezetimibe using a quality‐by‐design ...
Sani Ega Priani, Anis Yohana Chaerunisaa, Gofarana Wilar, Iyan Sopyan, Mozhgan Afshari   +4 more
wiley   +1 more source

Self-nanoemulsifying ramipril tablets: a novel delivery system for the enhancement of drug dissolution and stability

International Journal of Nanomedicine, 2019
Khalid F Alhasani,1 Mohsin Kazi,1,2 Mohamed Abbas Ibrahim,1 Ahmad A Shahba,1,2 Fars K Alanazi1,21Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia; 2Kayyali Chair for Pharmaceutical ...
Alhasani KF, Kazi M, Ibrahim MA, Shahba AA, Alanazi FK   +4 more
doaj  

Novel Solid Self-Nanoemulsifying Drug Delivery System (S-SNEDDS) for Oral Delivery of Olmesartan Medoxomil: Design, Formulation, Pharmacokinetic and Bioavailability Evaluation

Pharmaceutics, 2016
The main purpose of this study was to develop a solid self-nanoemulsifying drug delivery system (S-SNEDDS) of Olmesartan (OLM) for enhancement of its solubility and dissolution rate.
Ali Nasr, Ahmed Gardouh, Mamdouh Ghorab
doaj   +1 more source

Validasi Metode Spektrofotometri UV-VIS untuk Studi Kelarutan Pentagamavunon-0 di dalam Pembawa Self-Nanoemulsifying Drug Delivery System [PDF]

, 2017
Pentagamavunon-0 memiliki aktivitas anti-inflamasi yang tinggi namun kelarutan dan absorpsinya kurang, yang dapat diperbaiki dengan formulasi SNEDDS. Salah satu parameter penting optimasi SNEDDS adalah kelarutan PGV-0 dalam berbagai minyak, surfaktan, co-
Astuti, I. Y. (Ika), Marchaban, M. (Marchaban), Martien, R. (Ronny), Nugroho, A. E. (Agung)   +3 more
core  

Multitarget Anti‐Candida Activity of Thai Plant Extracts and Essential Oils: Inhibiting Biofilm Formation, Denture Adhesion, and Germ Tube Formation

Scientifica, Volume 2025, Issue 1, 2025.
This study aimed to evaluate the efficacy of Thai plant extracts (PEs) and essential oils (EOs) against reference and clinical isolate strains of Candida albicans, focusing on their ability to inhibit biofilm formation, cell adhesion to denture acrylic, and germ tube formation. The minimum biofilm inhibition concentration (MBIC) and the minimum biofilm
Premnapa Sisopa, Supaporn Lamlertthon, Ruchadaporn Kaomongkolgit, Pratthana Chomchalao, Waree Tiyaboonchai, Simone Carradori   +5 more
wiley   +1 more source

Enhancing Oral Bioavailability of Apigenin Using a Bioactive Self-Nanoemulsifying Drug Delivery System (Bio-SNEDDS): In Vitro, In Vivo and Stability Evaluations

Pharmaceutics, 2020
Apigenin (APG) is a very well-known flavonoid for its anti-inflammatory and anticancer properties. The purpose of this study is to improve the solubility and bioavailability of APG using a stable bioactive self-nanoemulsifying drug delivery system (Bio ...
Mohsin Kazi, Abdullah Alhajri, Sultan M. Alshehri, Ehab M. Elzayat, Osaid T. Al Meanazel, Faiyaz Shakeel, Omar Noman, Mohammad A. Altamimi, Fars K. Alanazi   +8 more
doaj   +1 more source