Results 11 to 20 of about 560,945 (139)
Biodistribution of sodium borocaptate (BSH) for boron neutron capture therapy (BNCT) in an oral cancer model [PDF]
Radiation and Environmental Biophysics, 2013 Boron neutron capture therapy (BNCT) is based on selective accumulation of ¹⁰B carriers in tumor followed by neutron irradiation. We previously proved the therapeutic success of BNCT mediated by the boron compounds boronophenylalanine and sodium decahydrodecaborate (GB-10) in the hamster cheek pouch oral cancer model. Based on the clinical relevance of
Garabalino, Marcela Alejandra +12 more
openaire +4 more sources
Cationized gelatin-HVJ envelope with sodium borocaptate improved the BNCT efficacy for liver tumors
Radiation Oncology, 2011 Background Boron neutron capture therapy (BNCT) is a cell-selective radiation therapy that uses the alpha particles and lithium nuclei produced by the boron neutron capture reaction.
Ono Koji +12 more
doaj +3 more sources
Boron delivery agents for neutron capture therapy of cancer
Cancer Communications, 2018 Boron neutron capture therapy (BNCT) is a binary radiotherapeutic modality based on the nuclear capture and fission reactions that occur when the stable isotope, boron-10, is irradiated with neutrons to produce high energy alpha particles.
Rolf F. Barth, Peng Mi, Weilian Yang
doaj +2 more sources
Boron‐10 carriers and their applications in boron neutron capture therapy
Precision Radiation OncologyBoron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang +7 more
doaj +2 more sources
A realistic appraisal of boron neutron capture therapy as a cancer treatment modality
Cancer Communications, 2018 Boron neutron capture therapy (BNCT) is a binary therapeutic modality based on the nuclear capture and fission reactions that occur when the stable isotope boron-10 is irradiated with neutrons to produce high-energy alpha particles and recoiling lithium ...
Rolf F. Barth, Zizhu Zhang, Tong Liu
doaj +2 more sources
Drug binding sites on Nat1.8 sodium channels [PDF]
, 2008 The voltage-gated sodium channel, Nav 1.8, is known to play an important role in pain signalling. In this thesis, the functional properties and drug binding sites of wild type and mutant Nav 1.8 sodium channel currents were studied in mammalian sensory ...
Browne, Liam Edward
core +6 more sources
Chemistry – A European Journal, Volume 29, Issue 63, November 13, 2023., 2023 Poly(glycerol) functionalized detonation nanodiamonds conjugated with boron‐10 cluster and active targeting moiety were designed and synthesized. The nanodrugs were taken up by tumor cells and exhibited boron neutron capture therapy (BNCT) efficacy upon thermal neutron irradiation.
Masahiro Nishikawa +4 more
wiley +1 more source
Advanced Functional Materials, Volume 33, Issue 42, October 13, 2023., 2023 Au‐B nanoparticles are obtained by an efficient laser‐assisted synthetic procedure and are designed to act as radiosensitizers for combined X‐ray radiotherapy and boron neutron capture therapy guided by computed tomography imaging, thus allowing innovative combined radiotherapy approaches, with great potential benefits for simultaneous treatment of ...
Stefano Scaramuzza +16 more
wiley +1 more source
Therapeutic nucleus-access BNCT drug combined CD47-targeting gene editing in glioblastoma
Journal of Nanobiotechnology, 2022 Glioblastoma is the most common brain primary malignant tumor with the highest mortality. Boron neutron capture therapy (BNCT) can efficiently kill cancer cells on the cellular scale, with high accuracy, short course and low side-effects, which is ...
Jiejian Chen +13 more
doaj +1 more source