CYTOPATHIC EFFECTS OF ACCELERATOR-BASED BORON NEUTRON CAPTURE THERAPY ON HUMAN GLIOBLASTOMA CELLS
Boron neutron capture therapy (BNCT) is a targeted therapy based on a selective damage to cancer cells due to the interaction between boron-10 isotope and neutron.
V. A. Byvaltsev +7 more
doaj +1 more source
Evaluation of a Novel Boron-Containing α-d-Mannopyranoside for BNCT
Boron neutron capture therapy (BNCT) is a unique anticancer technology that has demonstrated its efficacy in numerous phase I/II clinical trials with boronophenylalanine (BPA) and sodium borocaptate (BSH) used as 10B delivery agents.
Takao Tsurubuchi +19 more
doaj +1 more source
Boron neutron capture therapy (BNCT) is a cancer-selective radiotherapy that utilizes the cancer targeting 10B-compound. Cancer cells that take up the compound are substantially damaged by the high liner energy transfer (LET) particles emitted mainly ...
Hiroshi Fukuda
doaj +1 more source
Melting of sodium clusters in electron irradiated NaCl [PDF]
In this paper we present the results of the first systematic investigation of the geometrical properties of sodium nanoclusters in NaCl using the combined results of differential scanning calorimetry (DSC) and atomic force microscopy (AFM).
Bukharaev, A.A., +9 more
core +2 more sources
Glutathione accelerates sodium channel inactivation in excised rat axonal membrane patches [PDF]
The effects of glutathione were studied on the gating behaviour of sodium channels in membrane patches of rat axons. Depolarizing pulses from –120 to –40 mV elicited sodium currents of up to 500 pA, indicating the simultaneous activation of up to 250 ...
Quasthoff, Stefan +3 more
core +1 more source
STRUCTURAL REACTIONS OF CD-1 MICE HEART AND LIVER TO A SINGLE INJECTION OF BOROCAPTATE SODIUM
Boron neutron capture therapy is considered a promising method for the treatment of malignant tumors of the head and neck. It is believed that to increase the effectiveness of this type of therapy, the use of large doses of boron is required, which may entail damaging effects on healthy tissue.
Vladimir V. Kanygin +7 more
openaire +1 more source
The renin-angiotensin-aldosterone system during haemodialysis with acetate or bicarbonate at different dialysate sodium concentrations [PDF]
The hormones of the renin angiotensin aldosterone system were measured during regular haemodialysis with acetate or bicarbonate at dialysate sodium concentrations of 135, 140, 145, and 150 mmol/l.
Ress, K. M. +3 more
core +1 more source
Overview of Boron Neutron Capture Therapy: a Medical Aspect
Cancer is an abnormal growth of a cell due to the cell’s inability to control and maintain its proliferation, differentiation and apoptosis cycle. There are several methods to treat cancer; one of which is boron neutron capture therapy (BNCT).
Alan Anderson Bangun +1 more
doaj +1 more source
Aza-BODIPY: A New Vector for Enhanced Theranostic Boron Neutron Capture Therapy Applications
Boron neutron capture therapy (BNCT) is a radiotherapeutic modality based on the nuclear capture of slow neutrons by stable 10B atoms followed by charged particle emission that inducing extensive damage on a very localized level (
Ghadir Kalot +13 more
doaj +1 more source
Targeting of peptide‐binding receptors on cancer cells with peptide‐drug conjugates
Abstract Specifically addressing cell surface molecules on cancer cells facilitates targeted cancer therapies that offer the potential to selectively destroy malignant cells, while sparing healthy tissue. Thus, undesired side‐effects in tumor patients are highly reduced.
Dennis J. Worm +2 more
wiley +1 more source

