Results 41 to 50 of about 1,246,486 (176)
Regulated cell death pathways in the sodium iodate model: Insights and implications for AMD. [PDF]
Exp Eye Res, 2023 The sodium iodate (NaIO3) model of increased oxidative stress recapitulates dry AMD features such as patchy RPE loss, secondary photoreceptors, and underlying choriocapillaris death, allowing longitudinal evaluation of the retinal structure.
Upadhyay M, Bonilha VL.
europepmc +2 more sources
Sensitivity of the Dorsal-Central Retinal Pigment Epithelium to Sodium Iodate-Induced Damage Is Associated With Overlying M-Cone Photoreceptors in Mice. [PDF]
Invest Ophthalmol Vis Sci, 2022 Purpose Retinal pigment epithelium (RPE) degeneration is a leading cause of blindness in retinal degenerative diseases, but the mechanism of RPE regional degeneration remains largely unknown.
Lian L +10 more
europepmc +2 more sources
Redox Biology, 2020 Sorsby Fundus Dystrophy (SFD) is a rare inherited autosomal dominant macular degeneration caused by specific mutations in TIMP3. Patients with SFD present with pathophysiology similar to the more common Age-related Macular Degeneration (AMD) and loss of ...
Alyson Wolk +6 more
doaj +1 more source
Self-Assembling Tacrolimus Nanomicelles for Retinal Drug Delivery
Pharmaceutics, 2020 Neovascular age-related macular degeneration (AMD) is characterized by an increase in reactive oxygen species (ROS) and pro-inflammatory cytokines in the retinal pigment epithelium cells.
Vrinda Gote +3 more
doaj +1 more source
Direct Effect of Sodium Iodate on Neurosensory Retina [PDF]
Investigative Opthalmology & Visual Science, 2014 To systematically characterize the effects of NaIO3 on retinal morphology and function.NaIO3 at 10, 20, or 30 mg/kg was administered by retro-orbital injection into adult C57BL/6J mice. Phenotypic and functional changes of the retina were assessed at 1, 3, 5, and 8 days postinjection by fundus imaging, optical coherence tomography (OCT), ERG, and ...
Jinmei, Wang +3 more
openaire +2 more sources
Absence of histopathological changes in the retina of zebrafish treated with sodium iodate [PDF]
Journal of Veterinary Medical Science, 2018 Yoshinori Yamagiwa +2 more
exaly +2 more sources
Protection of retina by αB crystallin in sodium iodate induced retinal degeneration. [PDF]
PLoS ONE, 2014 Age-related macular degeneration (AMD) is a leading cause of blindness in the developed world. The retinal pigment epithelium (RPE) is a critical site of pathology in AMD and αB crystallin expression is increased in RPE and associated drusen in AMD.
Peng Zhou +5 more
doaj +1 more source
Optimizing the sodium iodate model: Effects of dose, gender, and age. [PDF]
Exp Eye Res, 2023 Sodium iodate (NaIO3) is a commonly used model for age-related macular degeneration (AMD), but its rapid and severe induction of retinal pigment epithelial (RPE) and photoreceptor degeneration can lead to the premature dismissal of potentially effective ...
Anderson BD +4 more
europepmc +2 more sources
A New, Eco-Friendly Method for Iodination of Activated Arenes
E-Journal of Chemistry, 2006 An effective, eco-friendly method for iodination of arenes is presented. The reaction of activated aromatics with a mixture of sodium iodate and sodium sulphite in the presence of hydrochloric acid gives mono iodoarenes in high yields.
R. Sathiyapriya, R. Joel Karunakaran
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Mesenchymal stem cells (MSC) are highly regarded as a potential treatment for retinal degenerative disorders like retinitis pigmentosa and age-related macular degeneration.
Avin Ee-Hwan Koh +18 more
doaj +1 more source