Results 1 to 10 of about 1,773,765 (367)

Laser solid-phase synthesis of single-atom catalysts [PDF]

open access: yesLight: Science & Applications, 2021
Synthesis of Pt single atom catalysts is achieved by one-step laser irradiation of “isolated” H2PtCl6 precursor on graphene oxide, via filtration and freeze-drying sublimation, by simultaneous pyrolysis of the precursor and reduction of graphene oxide.
Yudong Peng   +5 more
doaj   +3 more sources

Precise solid-phase synthesis of CoFe@FeOx nanoparticles for efficient polysulfide regulation in lithium/sodium-sulfur batteries. [PDF]

open access: yesNat Commun, 2023
Complex metal nanoparticles distributed uniformly on supports demonstrate distinctive physicochemical properties and thus attract a wide attention for applications.
Chen Y   +10 more
europepmc   +2 more sources

Heterocycles as a Peptidomimetic Scaffold: Solid-Phase Synthesis Strategies [PDF]

open access: yesPharmaceuticals, 2021
Peptidomimetics are a privileged class of pharmacophores that exhibit improved physicochemical and biological properties. Solid-phase synthesis is a powerful tool for gaining rapid access to libraries of molecules from small molecules to biopolymers and ...
Aizhan Abdildinova   +2 more
doaj   +2 more sources

Dielectrophoretic bead-droplet reactor for solid-phase synthesis [PDF]

open access: yesNature Communications
Solid-phase synthesis underpins many advances in synthetic and combinatorial chemistry, biology, and material science. The immobilization of a reacting species on the solid support makes interfacing of reagents an important challenge in this approach. In
Punnag Padhy   +8 more
doaj   +2 more sources

Greener solvents for solid-phase synthesis [PDF]

open access: yes, 2017
The use of a variety of green solvents to swell a diverse range of resins used in solid-phase synthesis is investigated. Good swelling is shown to depend on the structure of the resin and the solvent.
Lawrenson, Stefan   +3 more
core   +2 more sources

Novel Solution- and Solid-Phase Strategies for the Parallel and Combinatorial Synthesis of Small-Molecular-Weight Compound Libraries

open access: diamondCHIMIA, 1996
In this account dedicated to '100 years Roche' in CHIMIA, we present some of our strategies towards the synthesis of interesting novel amino-acid-derived building blocks; multigeneration synthesis of thiazole libraries in solution; a novel solid-
Alexander Chucholowski   +4 more
doaj   +5 more sources

The Facile Solid-Phase Synthesis of Thiazolo-Pyrimidinone Derivatives [PDF]

open access: yesMolecules
A thiazolo-pyrimidinone derivative library was developed through a facile solid-phase synthesis method. For the reaction, the thiazolo[4,5-d]pyrimidin-7(6H)-one structure was synthesized through efficient Thorpe–Ziegler and cyclization reactions.
Shuanghui Hua, Jimin Moon, Taeho Lee
doaj   +2 more sources

Combination of automated solid-phase and enzymatic oligosaccharide synthesis provides access to α(2,3)-sialylated glycans [PDF]

open access: yesChemical Communications, 2015
A synthetic strategy combining automated solid-phase chemical synthesis and enzymatic sialylation was developed to access α(2,3)-sialylated glycans.
Fair, Richard J.   +2 more
core   +2 more sources

Automated synthesis of prexasertib and derivatives enabled by continuous-flow solid-phase synthesis

open access: yesNature Chemistry, 2021
Recent advances in end-to-end continuous-flow synthesis are rapidly expanding the capabilities of automated customized syntheses of small-molecule pharmacophores, resulting in considerable industrial and societal impacts; however, many hurdles persist ...
Chenguang Liu   +9 more
semanticscholar   +1 more source

Efficient Syntheses of 1,2,3-Triazoloamide Derivatives Using Solid- and Solution-Phase Synthetic Approaches

open access: yesMolecules, 2015
Efficient synthetic routes for the preparation of secondary and tertiary 1,2,3-triazoloamide derivatives were developed. A secondary α-1,2,3-triazoloamide library was constructed and expanded by a previously developed solid-phase synthetic route and a ...
Doohyun Lee   +13 more
doaj   +1 more source

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