Results 1 to 10 of about 38,597 (264)
Parallel solid-phase synthesis of diaryltriazoles [PDF]
Beilstein Journal of Organic Chemistry, 2012 A series of substituted diaryltriazoles was prepared by a solid-phase-synthesis protocol using a modified Wang resin. The copper(I)- or ruthenium(II)-catalyzed 1,3-cycloaddition on the polymer bead allowed a rapid synthesis of the target compounds in a ...
Matthias Wrobel +2 more
doaj +5 more sources
CHIMIA, 1996 In this account dedicated to '100 years Roche' in CHIMIA, we present some of our strategies towards the synthesis of interesting novel amino-acid-derived building blocks; multigeneration synthesis of thiazole libraries in solution; a novel solid-
Alexander Chucholowski +4 more
doaj +5 more sources
Solid‐Phase Supports for Oligonucleotide Synthesis [PDF]
Current Protocols in Nucleic Acid Chemistry, 2000 AbstractThis unit begins with a discussion of the advantages and disadvantages of oligonucleotide synthesis using solid supports. The physical and chemical properties of solid‐phase supports are discussed in terms of their suitability for oligonucleotide synthesis. In addition, the unit outlines the properties of linkers used for transient or permanent
Richard T. Pon
openalex +7 more sources
Grafted supports in solid-phase synthesis [PDF]
Biopolymers, 2000 Solid-phase synthesis is greatly dependent on the solid phase. We are interested in the development of a "pellicular" type of solid support where a more mobile polymer is grafted to rigid plastics. Compared to low cross-linked microporous beads that dominate the field, this approach allows great flexibility of design, as plastics are available as ...
Firas Rasoul +8 more
openalex +4 more sources
Heterocycles as a Peptidomimetic Scaffold: Solid-Phase Synthesis Strategies
Pharmaceuticals, 2021 Peptidomimetics are a privileged class of pharmacophores that exhibit improved physicochemical and biological properties. Solid-phase synthesis is a powerful tool for gaining rapid access to libraries of molecules from small molecules to biopolymers and ...
Aizhan Abdildinova +2 more
doaj +1 more source
Synlett, 1998 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Harry C. J. Ottenheijm +3 more
openaire +2 more sources
Molecules, 2015 Efficient synthetic routes for the preparation of secondary and tertiary 1,2,3-triazoloamide derivatives were developed. A secondary α-1,2,3-triazoloamide library was constructed and expanded by a previously developed solid-phase synthetic route and a ...
Doohyun Lee +13 more
doaj +1 more source
First total synthesis of hoshinoamide A
Beilstein Journal of Organic Chemistry, 2021 Hoshinoamides A, B and C, linear lipopeptides, were isolated from the marine cyanobacterium Caldora penicillata, with potent antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum.
Haipin Zhou +5 more
doaj +1 more source
ChemEngineering, 2020 Coal gasification is a new direction for the clean utilization of coal, but it also brings huge environmental pressure on solid waste. In this paper, the high-crystallinity single-phase zeolite A was prepared by solid-phase alkali fusion synthesis from ...
Wenxin Ji +10 more
doaj +1 more source
Solid Phase versus Solution Phase Synthesis of Heterocyclic Macrocycles
Molecules, 2013 Comparing a solution phase route to a solid phase route in the synthesis of the cytotoxic natural product urukthapelstatin A (Ustat A) confirmed that a solid phase method is superior.
Shelli R. McAlpine, Seong Jong Kim
doaj +1 more source