Results 21 to 30 of about 1,115,644 (325)

Effect of synthesis conditions on formation pathways of metal organic framework (MOF-5) Crystals [PDF]

open access: yes, 2013
Metal Organic Frameworks (MOFs) represent a class of nanoporous crystalline materials with far reaching potential in gas storage, catalysis, and medical devices.
A. D. C. Burrows K.   +29 more
core   +1 more source

Solid Phase versus Solution Phase Synthesis of Heterocyclic Macrocycles

open access: yesMolecules, 2013
Comparing a solution phase route to a solid phase route in the synthesis of the cytotoxic natural product urukthapelstatin A (Ustat A) confirmed that a solid phase method is superior.
Shelli R. McAlpine, Seong Jong Kim
doaj   +1 more source

Solution-phase synthesis of pyrrole-imidazole polyamides [PDF]

open access: yes, 2009
Pyrrole−imidazole polyamides are DNA-binding molecules that are programmable for a large repertoire of DNA sequences. Typical syntheses of this class of heterocyclic oligomers rely on solid-phase methods. Solid-phase methodologies offer rapid assembly on
Chenoweth, David M.   +2 more
core   +3 more sources

Solid-Phase Synthesis of Megamolecules

open access: yesJournal of the American Chemical Society, 2020
This paper presents a solid-phase strategy to efficiently assemble multiprotein scaffolds-known as megamolecules-without the need for protecting groups and with precisely defined nanoscale architectures. The megamolecules are assembled through sequential reactions of linkers that present irreversible inhibitors for enzymes and fusion proteins ...
Blaise R. Kimmel   +4 more
openaire   +4 more sources

High throughput synthesis of 2,5-substituted indoles using a titanium carbenoid bearing boronate functionality [PDF]

open access: yes, 2008
A titanium benzylidene complex bearing a boronate group converted resin-bound esters into enol ethers. Suzuki cross-coupling with aryl iodides followed by cleavage with acid completed the solid-phase synthesis of 2,5-disubstituted N-Boc-indoles.
Hartley, R.C.   +3 more
core   +1 more source

HOBt·DCHA-Mediated Synthesis of Sterically Hindered Peptides employing Fmoc-Amino Acid Chlorides in Both Solution-Phase and Solid Phase Methods [PDF]

open access: yes, 2008
The synthesis of peptides employing Fmoc-amino acid chlorides in presence of HOBt·DCHA salt in solution as well as by the solid-phase methods is described. The coupling was found to be complete in 30 min and free from racemization.
Krishna, G.C.   +2 more
core   +1 more source

Synthesis of Peptoids Containing Multiple Nhtrp and Ntrp Residues: A Comparative Study of Resin, Cleavage Conditions and Submonomer Protection

open access: yesFrontiers in Chemistry, 2020
Peptoids hold status as peptide-mimetics with versatile biological applications due to their proteolytic stability and structural diversity. Among those that have been studied in different biological systems, are peptoids with dominant balanced ...
Abdullah Lone   +5 more
doaj   +1 more source

Use of continuous solid-phase synthesis to obtain phosphors based on strontium aluminate [PDF]

open access: yes, 2016
The effect of conditions of continuous solid-phase synthesis on particle size distribution of nanostructured powders of strontium aluminate was studied.
Falkovich, Yulia Valerievna   +3 more
core   +1 more source

Total wash elimination for solid phase peptide synthesis

open access: yesNature Communications, 2023
We present a process for solid phase peptide synthesis (SPPS) that completely eliminates all solvent intensive washing steps during each amino acid addition cycle.
Jonathan M. Collins   +6 more
doaj   +1 more source

Magnetic nanoparticle-based solid phase peptide synthesis and the synchronous detection of their biological activity

open access: yesMaterials Today Advances, 2021
The solid-phase peptide synthesis (SPPS) strategy, as the main procedure of peptide manufacturing, has a profound impact on the research of peptides.
D. Luo   +8 more
doaj   +1 more source

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