Results 31 to 40 of about 1,859,179 (392)
Molecules, 2011 The solid-phase synthesis of the first example of a new diphosphate AICAR derivative is reported. The new substance is characterized by the presence of a 5'-phosphate group while a second phosphate moiety is installed on a 5-hydroxypentyl chain attached ...
Gennaro Piccialli +7 more
doaj +1 more source
Boosting Fmoc Solid-Phase Peptide Synthesis by Ultrasonication.
Organic Letters, 2019 We investigated the ultrasonication-mediated effects on the Fmoc-based solid-phase peptide synthesis (SPPS). Our study culminated with the development of an ultrasound-assisted strategy (US-SPPS) that allowed for the synthesis of different biologically ...
F. Merlino +8 more
semanticscholar +1 more source
Parallel solid-phase synthesis of diaryltriazoles
Beilstein Journal of Organic Chemistry, 2012 A series of substituted diaryltriazoles was prepared by a solid-phase-synthesis protocol using a modified Wang resin. The copper(I)- or ruthenium(II)-catalyzed 1,3-cycloaddition on the polymer bead allowed a rapid synthesis of the target compounds in a ...
Matthias Wrobel +2 more
doaj +1 more source
New Solid Phase Synthesis of Distamycin Analogues
Molecules, 2011 A novel and straightforward solid phase synthesis of distamycin analogues containing benzene units has been developed.
Drozdowska Danuta
doaj +1 more source
Molecules, 2014 Dendritic structures, being highly homogeneous and symmetric, represent ideal scaffolds for the multimerization of bioactive molecules and thus enable the synthesis of compounds of high valency which are e.g., applicable in radiolabeled form as ...
Gabriel Fischer +2 more
doaj +1 more source
An overview of recent progress in modern synthetic approach—combinatorial synthesis
Beni-Suef University Journal of Basic and Applied Sciences, 2020 Background In recent times, a powerful tool of combinatorial synthesis has been used for the preparation of large chemical entities through a small set up of reactions between different building blocks using solid-phase and solution-phase techniques ...
Chandravadivelu Gopi +3 more
doaj +1 more source
Solid-Phase Synthesis of ?-Oligopeptides
CHIMIA, 1997 Fmoc-N-Protected ?-amino acids of (S)-configuration bearing the side chains of Ala, Val, Leu, and Phe in the 3- and 2-position have been prepared. Manual solid-phase synthesis (ortho-chlorotrityl-chloride resin) of the ?-heptapeptides H-?3-HVal-?
Gilles Guichard, Dieter Seebach
doaj +2 more sources
Novel sulfur and selenium containing bis-α-amino acids from 4-hydroxyproline [PDF]
, 2010 The synthesis of new substituted prolines carrying at C-4 a second α-amino acid residue is reported. The amino acid, l-cysteine or l-selenocysteine, is linked to the proline ring through the sulfur or the selenium atom, respectively.
CAPUTO, ROMUALDO +4 more
core +1 more source
Materials Today Advances, 2021 The solid-phase peptide synthesis (SPPS) strategy, as the main procedure of peptide manufacturing, has a profound impact on the research of peptides.
D. Luo +8 more
doaj +1 more source
Solid-phase synthesis of recyclable diphosphine ligands [PDF]
, 2015 The authors thank the European Union (Marie Curie ITN SusPhos, Grant Agreement No. 317404 and COST action PhoSciNet cm08602) for financial support.An efficient solid-phase synthetic approach towards diphosphine ligands is demonstrated.
Heutz, Frank +2 more
core +1 more source