Photolabile Linkers for Solid-Phase Synthesis.
Photolabile linkers are the subjects of intense research because they allow the release of the target molecule simply by irradiation. Photochemical release of synthesis products is often facilitated without additional reagents under mild reaction ...
R. J. T. Mikkelsen +4 more
semanticscholar +1 more source
Mechanochemical synthesis of AlCoCrFeNi powders via high-energy ball milling
AlCoCrFeNi powders in equimolar ratios were synthesized by mechanochemical synthesis on a high-energy ball milling machine (HEBM). The elemental and phase composition of AlCoCrFeNi powders before and after mechanochemical synthesis were investigated by ...
Е.Е. Камбаров +3 more
doaj +1 more source
Iron-stabilized nanocrystalline ZrO2 solid solutions: Synthesis by combustion and thermal stability [PDF]
The synthesis of Fe3+-stabilized zirconia by the nitrate/urea combustion route was investigated. Using several characterization techniques, including X-ray diffraction, field-emission-gun scanning electron microscopy and notably Mo¨ ssbauer spectroscopy,
Barnabé, Antoine +5 more
core +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Novel Solution- and Solid-Phase Syntheses of Heterocyclic Systems
Heterocyclic compounds are an attractive source of screening library structures because they possess varied structural diversity and can exhibit potent biological activity.
Gaelle Cabon +4 more
doaj +1 more source
Cross Metathesis Assisted Solid-Phase Synthesis of Glycopeptoids [PDF]
A solid-phase synthesis of glycopeptoids was explored through olefin cross metathesis (CM). Peptoids and sugar derivatives with appropriate olefin moieties were coupled in the presence of an olefin metathesis catalyst to afford glycopeptoids in good ...
Grubbs, Robert H. +3 more
core +1 more source
Cyclative cleavage via solid-phase supported stabilized sulfur ylides: synthesis of macrocyclic lactones [PDF]
A new synthesis of macrolactones bearing a cyclopropyl ring condensed to the macrocycle is reported via a cyclization-release strategy making use of solid-phase supported stabilized sulfur ...
CARDULLO F +6 more
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Organic Synthesis on Solid Phase. (Supports, Linkers, Reactions)
n ...
Florencio Zaragoza Dörwald
doaj +1 more source
Crystal structure and conductivity of bismuth-containing complex oxides [PDF]
In the paper, a comprehensive systematic study of different classes of bismuth containing oxide compounds was carried out. The relationship between composition, temperature and concentration regions of existence of stable, specific structure and ...
Buyanova, E. S. +6 more
core +2 more sources

