Results 81 to 90 of about 24,357,552 (149)

Orlistat-loaded solid SNEDDS for the enhanced solubility, dissolution, and in vivo performance

International Journal of Nanomedicine, 2018
Dae Hun Kim,1,* Jae Yeol Kim,1,* Rae Man Kim,1 Pooja Maharjan,1 Yu-Geun Ji,2 Dong-Jin Jang,3 Kyoung Ah Min,1 Tae-Sung Koo,2 Kwan Hyung Cho1 1Department of Pharmacy, Inje Institute of Pharmaceutical Sciences and Research, Inje University, Gimhae ...
Kim DH, Kim JY, Kim RM, Maharjan P, Ji YG, Jang DJ, Min KA, Koo TS, Cho KH   +8 more
doaj  

Formulation Development of Solid Self-Nanoemulsifying Drug Delivery Systems of Quetiapine Fumarate via Hot-Melt Extrusion Technology: Optimization Using Central Composite Design

Pharmaceutics
Quetiapine fumarate (QTF) was approved for the treatment of schizophrenia and acute manic episodes. QTF can also be used as an adjunctive treatment for major depressive disorders. QTF oral bioavailability is limited due to its poor aqueous solubility and
Prateek Uttreja, Ahmed Adel Ali Youssef, Indrajeet Karnik, Kavish Sanil, Nagarjuna Narala, Honghe Wang, Rasha M. Elkanayati, Sateesh Kumar Vemula, Michael A. Repka   +8 more
doaj   +1 more source

Enhanced Anti-Inflammatory Activity of Kaempferia galanga Extract by Solid Self-Nanoemulsifying Drug Delivery System and Its Development in Fast Disintegrating Tablet

Science and Technology Indonesia
The increasing global incidence of osteoarthritis (OA) emphasizes the need for effective treatments, particularly for the elderly. Conventional OA treatments pose administration challenges, leading to patient discomfort due to difficulties in ...
Salma Latifani, Annisa nur Fitriani, Paniroy, Kadek Sanitha Maesayani, Juan Freddy, Oktavia Rahayu Adianingsih   +5 more
doaj   +1 more source

Comparative Bioavailability Study of Solid Self-Nanoemulsifying Drug Delivery System of Fenofibric Acid in Healthy Male Subjects. [PDF]

Med Princ Pract, 2022
Suhery WN, Mudhakir D, Sumirtapura YC, Pamudji JS.   +3 more
europepmc   +1 more source

Insights into the biopharmaceutical behavior of oral lipid-based formulations using advanced analytical techniques and mathematical modeling [PDF]

, 2014
Lipid-based formulations (LBFs) are effective means for the oral delivery of poorly water-soluble compounds. The drug is already solubilized in the formulation and, thus, the critical dissolution step is circumvented. However, the oral bioavailability is
Stillhart, Cordula Edith
core   +1 more source

Evaluating Various Lactose Types as Solid Carriers for Improving Curcumin Solubility in Solid Self-Nanoemulsifying Drug Delivery Systems (S-SNEDDSs) for Oral Administration

Sci
Curcumin, a bioactive compound derived from turmeric, possesses numerous pharmaceutical properties; however, its poor aqueous solubility and permeability result in low bioavailability. This study aims to develop a solid self-nanoemulsifying drug delivery
Panida Teerapipattanapong, Pimrada Jaikon, Nichapa Ningsanonda, Etsuo Yonemochi, Takayuki Furuishi, Namon Hirun, Pakorn Kraisit   +6 more
doaj   +1 more source

Preparation and evaluation of a self-nanoemulsifying drug delivery system loaded with Akebia saponin D–phospholipid complex

, 2016
Jinyang Shen,1 Jianping Bi,2 Hongli Tian,1 Ye Jin,1 Yuan Wang,3 Xiaolin Yang,4 Zhonglin Yang,1 Junping Kou,5 Fei Li1 1State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 2Shandong Provincial Traditional Chinese Medical ...
Yang X, Yang Z, Shen J, Tian H, Li F, Jin Y, Wang Y, Bi J, Kou J   +8 more
core  

Development of self-nanoemulsifying drug delivery systems for the enhancement of solubility and oral bioavailability of fenofibrate, a poorly water-soluble drug

, 2016
Kazi Mohsin,1 Rayan Alamri,1 Ajaz Ahmad,2 Mohammad Raish,3 Fars K Alanazi,1 Muhammad Delwar Hussain4 1Kayyali Chair for Pharmaceutical Industry, Department of Pharmaceutics, 2Department of Clinical Pharmacy, 3Department of Pharmaceutics, College of ...
Ahmad A, Moshin K, Alamri R, Alanazi FK, Hussain MD, Raish M   +5 more
core  

ePoster

European Journal of Neurology, Volume 32, Issue S1, June 2025.
wiley   +1 more source

Supersaturable solid self-microemulsifying drug delivery system: precipitation inhibition and bioavailability enhancement

, 2017
Guilan Quan,1 Boyi Niu,1 Vikramjeet Singh,1 Yixian Zhou,1 Chuan-Yu Wu,2 Xin Pan,1 Chuanbin Wu1 1School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China; 2Department of Chemical and Process Engineering, University of Surrey, Guildford,
Niu B, Pan X, Wu C, Zhou Y, Quan G, Singh V   +5 more
core