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The Concept of Growth Hormone Deficiency Affecting Clinical Prognosis in IVF [PDF]
Frontiers in Endocrinology, 2019 The current understanding of human growth hormone (hGH; here GH) action is that the molecule is a 191-amino acid, single-chain polypeptide that is synthesized, stored and secreted by the somatotroph cells within the lateral wings of the anterior ...
John L. Yovich +6 more
doaj +2 more sources
The Somatomedin Hypothesis: 2001 [PDF]
Endocrine Reviews, 2001 AbstractSince the original somatomedin hypothesis was conceived, a number of important discoveries have allowed investigators to modify the concept. Originally somatic growth was thought to be controlled by pituitary GH and mediated by circulating insulin-like growth factor-I (IGF-I, somatomedin C) expressed exclusively by the liver. With the discovery
Jun-Li Liu +4 more
+5 more sources
Somatolactogens, somatomedins, and immunity.
Journal of Dairy Science, 1993 The neuroendocrine and immune systems participate as active partners in host homeostatic and defense mechanisms. This partnership involves a complex intercommunication system employing an array of shared ligands and receptors. Hormones of the somatolactogen family have marked influences on immune events in vivo, including the maintenance of lymphoid ...
S. Arkins, R. Dantzer, K. Kelley
semanticscholar +4 more sources
Cushing Syndrome Associated Myopathy: It Is Time for a Change [PDF]
Endocrinology and Metabolism, 2021 Cushing syndrome is the result of excessive levels of glucocorticoids. Endogenous Cushing syndrome is rare with an incidence of two to three cases per million per year.
Martin Reincke
doaj +1 more source
Prognostic significance of growth hormone in pediatric liver transplantation
Вестник трансплантологии и искусственных органов, 2023 Growth hormone (GH) plays a leading role in the regulation of cell and tissue metabolism and growth. Its effects are mediated through the so-called somatomedins, among which the most important is the liver-produced insulinlike growth factor 1 (IGF-1). It
R. M. Kurabekova +8 more
doaj +1 more source
Insulin-like Growth Factors in a clinical setting: Review of IGF-I
Biomedical Papers, 2015 Background and Aims: Interest in growth hormone (GH) is inextricably linked to the need for in depth understanding of the somatomedins (insulin-like growth factors) which are polypeptides structurally similar to insulin and with broad physiological ...
Zdenek Frysak +3 more
doaj +1 more source
Parathyroid localization [PDF]
, 1986 Twenty-nine consecutive patients with suspected primary hyperparathyroidism were examined preoperatively using ultrasound, sonographically guided fine needle aspiration, and aspirate immunostaining for PTH.
Borisch, B. +7 more
core +1 more source
Journal of Physiological Anthropology, 2019 Background Epidemiological data regarding the association between serum levels of IGF-I and bone mineral acquisition during childhood are scarce. Here, we investigated the association between serum levels of IGF-I and bone status during puberty.
Katsuyasu Kouda +5 more
doaj +1 more source
Identification and characterization of insulin-like growth factor receptors on adult rat cardiac myocytes: linkage to inositol 1,4,5-trisphosphate formation. [PDF]
, 1992 Cultured cardiac myocytes from adult Sprague-Dawley rats express both insulin-like growth factor-I (IGF-I) receptors and insulin-like growth factor-II/mannose 6-phosphate (IGF-II/Man6P) receptors and respond to IGF-I with a dose-dependent accumulation of
Berg, Ingeborg +5 more
core +1 more source
Insulin-Like Growth Factor II (IGF-II) Is More Potent Than IGF-I in Stimulating Cortisol Secretion from Cultured Bovine Adrenocortical Cells: Interaction with the IGF-I Receptor and IGF-Binding Proteins [PDF]
, 1995 Although the stimulating effect of insulin-like growth factor I (IGF-I) on adrenal steroidogenesis has been well established, the role of IGF-II in the adult adrenal gland remains unknown.
Engelhardt, Dieter +3 more
core +1 more source