Results 11 to 20 of about 7,600 (256)

Recurrent reactive hypoglycemia due to clozapine‐induced glucose intolerance: A case report

Psychiatry and Clinical Neurosciences Reports, Volume 2, Issue 4, December 2023., 2023
Early intervention for impaired glucose tolerance may prevent clozapine discontinuation due to diabetes or hyperglycemia. Abstract Background Although diabetes is one of the most common side effects of clozapine, a medication for the treatment of schizophrenia, to the best of our knowledge no study exists on clozapine‐induced glucose intolerance or ...
Fumihiko Kawai, Satsuki Watanabe, Hirotaka Ebihara, Naoki Shimizu, Shiori Oshima, Hiroshi Okai, Yoshiko Murata, Hisatoshi Arai, Koji Matsuo   +8 more
wiley   +1 more source

Astragalus polysaccharide ameliorates insulin resistance in HepG2 cells through activating the STAT5/IGF‐1 pathway

Immunity, Inflammation and Disease, Volume 11, Issue 11, November 2023., 2023
Abstract Background Insulin resistance (IR) is considered as a major factor initiating type 2 diabetes mellitus and can lead to a reduction in glucose uptake that mainly occurs in the liver. Astragalus polysaccharide (APC), extracted from the traditional Chinese medicine, has been recorded to suppress IR.
Xinxin Yue, Wei Hao, Min Wang, Yang Fu
wiley   +1 more source

SIOP PODC–adapted treatment guidelines for craniopharyngioma in low‐ and middle‐income settings

Pediatric Blood &Cancer, Volume 70, Issue 11, November 2023., 2023
Abstract Pediatric craniopharyngioma is a rare tumor with excellent survival but significant long‐term morbidities due to the loco‐regional tumor growth or secondary to its treatment. Visual impairment, panhypopituitarism, hypothalamic damage, and behavioral changes are among the main challenges.
Nisreen Amayiri, Ariane Spitaels, Mohamed Zaghloul, Anthony Figaji, Sergio Cavalheiro, Hermann L. Muller, Moawia Elhassan, Jeannette Parkes, Naureen Mushtaq, Mohamed El Beltagy, Yacoub A. Yousef, Natia Esiashvili, Michael Sullivan, Marcos Devanir da Costa, Patricia Dastoli, Fatima Mubarak, Ute Bartels, Omar Chamdine, Alan Davidson, Awni Musharbash, Patricia Alcasabas, Eric Bouffet, Simon Bailey   +22 more
wiley   +1 more source

Acute abdominal pain due to atypical bilateral adrenal infarction in acute myeloid leukemia with alterations related to myelodysplasia: A case report

Clinical Case Reports, Volume 11, Issue 10, October 2023., 2023
Thoracoabdominal computed tomography with contrast enhancement on admission revealed diffusely enlarged bilateral adrenal glands with diffuse internal low‐attenuation areas. We report a case of abdominal pain and adrenal insufficiency due to AML‐induced adrenal infarction.
Risa Hirata, Masaki Tago, Shun Yamashita, Satsuki Yamamoto, Shizuka Yaita, Yuka Hirakawa, Maiko Ono, Shu‐ichi Yamashita   +7 more
wiley   +1 more source

Early life interventions metformin and trodusquemine metabolically reprogram the developing mouse liver through transcriptomic alterations. [PDF]

Aging Cell
This study examined the effects of metformin (MF) and trodusquemine (MSI‐1436) on the livers of young, developing mice. We discovered that MSI‐1436 significantly alters mRNA and miRNA expression more potently than MF, impacting key metabolic pathways.
Ashiqueali SA, Schneider A, Zhu X, Juszczyk E, Mansoor MAM, Zhu Y, Fang Y, Zanini BM, Garcia DN, Hayslip N, Medina D, McFadden S, Stockwell R, Yuan R, Bartke A, Zasloff M, Siddiqi S, Masternak MM.   +17 more
europepmc   +2 more sources

Expression of the insulin-like growth factor-II/mannose-6-phosphate receptor in multiple human tissues during fetal life and early infancy [PDF]

, 1992
The insulin like growth factor-II/mannose-6-phosphate (IGF-II/M6P) receptor has been detected in many cells and tissues. In the rat, there is a dramatic developmental regulation of IGF-II/M6P receptor expression, the receptor being high in fetal and ...
Eisenmenger, Wolfgang, Funk, B., Hansmann, A., Kessler, U., Kiess, W., Kolb, H. J.   +5 more
core   +1 more source

Transfer of insulin-like growth factors I and II from plasma to lymph in young goats [PDF]

, 1992
The plasma clearance of intravenously injected '25I-labelled insulin-like growth factor I (IGFI, n = 13) and IGF-II (n = 12) and their transfer into lymph draining the foreleg of 3 5- to 8- week-old British Saanen goats was studied.
Baucells Sánchez, María Dolores, Fleet, I.R., Prosser, C.G.   +2 more
core   +2 more sources

Insulin-like growth factor-I and its binding proteins in healthy mothers and their newborns [PDF]

Einstein (São Paulo), 2004
Objective: To determine serum levels of insulin-like growth factor-I, free insulin-like growth factor-I and its binding proteins in maternalserum and in cord blood of two groups of newborns with differentbirth weights.
Rosanna Velleca Lima, Daniel Giannella Neto, Conceição Aparecida de Mattos Segre, Saul Goldenberg   +3 more
doaj  

Thyroxine-binding globulin: investigation of microheterogeneity [PDF]

, 1981
Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland, Henze, R., Horn, K., Pickardt, C. R., Scriba, Peter Christian   +4 more
core   +1 more source

A high‐resolution data set of fatty acid‐binding protein structures. III. Unexpectedly high occurrence of wrong ligands

Acta Crystallographica Section D, Volume 81, Issue 8, Page 451-464, August 2025.
Very high‐resolution fatty acid‐binding protein structures identified a substantial number of ligands that differ strongly from their expected structure. If different ligand chemistry is a potentially overlooked problem in other, lower resolution, crystal structures of protein–ligand complexes, it has repercussions for any study using such structures ...
Andreas Ehler, Christian Bartelmus, Joerg Benz, Inken Plitzko, Markus G. Rudolph   +4 more
wiley   +1 more source