Results 101 to 110 of about 136,487 (285)
Piezo2 in Mechanosensory Biology: From Physiological Homeostasis to Disease‐Promoting Mechanisms
Cell Proliferation, EarlyView.Piezo2 channels are essential mechanotransducers regulating touch, proprioception and visceral mechanosensation across physiological systems, emerging as therapeutic targets for pathological mechanical hypersensitivity and neurogenic disorders. ABSTRACT Piezo2, a mechanically activated ion channel, serves as the key molecular transducer for touch ...
Zhebin Cheng +4 more
wiley +1 more source
Evaluation of the VP22 gene adjuvant for enhancement of DNA vaccine against somatostatin in mice
Animal, 2008 Somatostatin (SS) is a hormone that inhibits the secretion of growth hormone. Immunization against SS can promote the growth of animals. A novel SS-VP22 fused vaccine, pEGS2SS-V, was constructed from pEGS2SS plasmid with a VP22 gene fragment.
Li. Han +8 more
doaj +1 more source
Alterations in Somatostatin mRNA Expression in the Dorsolateral Prefrontal Cortex of Subjects with Schizophrenia or Schizoaffective Disorder [PDF]
, 2008 Harvey M. Morris +2 more
openalex +1 more source
Erythematous Papules and Plaques in an Infant Receiving Glucagon Therapy
JEADV Clinical Practice, EarlyView.
Sara Al Janahi +4 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective Focal cortical dysplasia (FCD) is a developmental malformation of the cerebral cortex and a leading cause of drug‐resistant epilepsy in children and young adults. Disruption of the excitation–inhibition (E–I) balance is a hallmark of neuronal hyperexcitability in FCD, yet the underlying synaptic ultrastructural changes remain poorly ...
Gyu Hyun Kim +6 more
wiley +1 more source
Epilepsia, EarlyView.Abstract This study was undertaken to systematically evaluate the efficacy of cell therapy in reducing seizures in animal models of chronic epilepsy. Three databases, Ovid MEDLINE, Ovid Embase, and Web of Science, were searched using predetermined eligibility criteria.
Afaf S. Altalhi +6 more
wiley +1 more source
Focal Spot, Fall/Winter 1993 [PDF]
, 1993 https://digitalcommons.wustl.edu/focal_spot_archives/1065/thumbnail ...
core +1 more source
Activation of somatostatin receptors attenuates pulmonary fibrosis [PDF]
, 2007 Raphaël Borie +8 more
openalex +1 more source
Epilepsia, EarlyView.Abstract Objective Neuropeptides have garnered great interest as potential treatments for epilepsy due to their impact on neuronal excitability through modulation of ion channels and neurotransmitter receptor activity. Neuropeptide Y (NPY) is a 36‐amino acid neuropeptide that is expressed primarily by γ‐aminobutyric acidergic (GABAergic) interneurons ...
Samantha L. Reed +8 more
wiley +1 more source
Folia Histochemica et Cytobiologica, 2012 The present study provides a detailed description of somatostatin (SOM) distribution and the colocalization pattern of SOM, neuropeptide Y (NPY) and nitric oxide synthase (NOS) in the dorsal striatum (caudate-putamen complex) of the guinea pig.
Janusz Najdzion +6 more
doaj +1 more source