Fast activity chirp patterns in focal seizures from patients and animal models
Abstract Time–frequency analysis of focal seizure electroencephalographic signals performed with depth electrodes in human temporal lobe structures has revealed the occurrence at onset of oscillations at approximately 30–100 Hz that feature a monotonic rapid decay in frequency content.
Maxime Lévesque+6 more
wiley +1 more source
Somatostatin Inhibition of Insulin and Glucagon Secretion in Rat Islet Culture: Reversal by Ionophore A231871 [PDF]
Wilfred Y. Fujimoto, John W. Ensinck
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Contribution of perineuronal nets to hyperexcitability in pilocarpine‐induced status epilepticus
Abstract Objective Changes in extracellular matrix (ECM) and highly condensed ECM structures called perineuronal nets (PNNs) have been reported in human patients with epilepsy as well as some animal models of epilepsy. We studied potential ECM changes in a mouse model of pilocarpine‐induced status epilepticus (PISE) and their potential contributions to
AnnaLin M. Woo+3 more
wiley +1 more source
AN ANALYSIS OF THE NEGATIVE INOTROPIC ACTION OF SOMATOSTATIN [PDF]
Rémi Quirion+3 more
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Abstract Objective Dravet syndrome (DS) is a severe neurodevelopmental disorder caused by pathogenic variants in the SCN1A gene, which encodes the voltage‐gated sodium channel Nav1.1 α subunit. Experiments in animal models of DS—including the haploinsufficient Scn1a+/− mouse—have identified impaired excitability of interneurons in the hippocampus and ...
Limei Zhu+5 more
wiley +1 more source
Use of octadecasilyl-silica for the extraction and purification of peptides in biological samples. Application to the identification of circulating metabolites of corticotropin-(1-24)-tetracosapeptide and somatostatin in vivo [PDF]
H.P.J. Bennett+3 more
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Neocortical neurogenesis: a proneural gene perspective
The neocortex is a mammalian‐specific brain region responsible for higher‐order cognitive functioning that shares fundamental similarities across species, but which is larger and more complex in humans. Proneural genes, encoding basic helix–loop–helix transcription factors (TFs), are evolutionarily conserved drivers of neurogenesis from fly to human ...
Lakshmy Vasan+3 more
wiley +1 more source
Gastric acid secretion in uraemia and circulating levels of gastrin, somatostatin, and pancreatic polypeptide. [PDF]
Roger Hällgren+3 more
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Helicobacter pylori Infection and Eradication in Relation to Gastroesophageal Reflux Disease
ABSTRACT Background and Aim The effect of Helicobacter pylori (H. pylori) infection and eradication on the risk of gastroesophageal reflux disease (GERD) is still unclear. Methods We conducted a systematic review with a comprehensive literature search in the bibliographic databases Embase, Medline, and Cochrane Library through May 2024.
Hejie Wang+8 more
wiley +1 more source
Single cellular origin of somatostatin and calcitonin in the rat thyroid gland [PDF]
Susan Van Noorden+2 more
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