Abstract Objective Accumulating evidence indicates that aberrant C1q‐C3 complement signaling in microglia and astrocytes drives synaptic dysfunction and neuronal loss. C1q‐mediated synaptic dysfunction disrupts neuronal circuitry balance and can lead to network hyperexcitability in epilepsy.
Yoonyi Jeong +5 more
wiley +1 more source
We used Neuromolecular Imaging (NMI) and trademarked BRODERICK PROBE® mini-implantable biosensors, to selectively and separately detect neurotransmitters in vivo, on line, within seconds in the dorsal striatal brain of the Parkinson’s Disease (PD) animal
Patricia A. Broderick, Edwin H. Kolodny
doaj +1 more source
Attribute Preferences for Somatostatin Analogues in Neuroendocrine Tumours (NETs) Among Patients, Clinicians and Nurses in Australia. [PDF]
ABSTRACT Background Long‐acting somatostatin analogues (LA SSAs) are commonly used as first‐line treatment in well‐differentiated low and intermediate grade 1–2 gastroenteropancreatic neuroendocrine tumours (GEP‐NETs). As a long‐term treatment option for NETs, treatment preferences should be taken into consideration.
Fifer SJ +3 more
europepmc +2 more sources
First Ex-Vivo Validation of a Radioguided Surgery Technique with beta- Radiation
Purpose: A radio-guided surgery technique with beta- -emitting radio-tracers was suggested to overcome the effect of the large penetration of gamma radiation.
Bocci, V. +23 more
core +1 more source
ABSTRACT Background Amyloidosis is a rare, multisystem disorder characterized by extracellular deposition of misfolded protein fibrils. Gastrointestinal (GI) amyloidosis is uncommon but under‐recognized due to nonspecific symptoms, but early diagnosis is critical to improve quality of life and prognosis.
Myo Jin Tang +3 more
wiley +1 more source
Pegvisomant in combination or pegvisomant alone after failure of somatostatin analogs in acromegaly patients: an observational French ACROSTUDY cohort study [PDF]
Emmanuelle Kuhn +12 more
openalex +1 more source
Supplementary Data from Reexpression of <i>Human Somatostatin Receptor Gene 2</i> Gene Mediated by Oncolytic Adenovirus Increases Antitumor Activity of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand against Pancreatic Cancer [PDF]
Zhenwei Zhang +8 more
openalex +1 more source
Abstract Gastric, duodenal and rectal neuroendocrine tumours (NETs) are increasingly detected due to advances in endoscopic imaging. While international guidelines provide criteria for endoscopic management, several aspects remain controversial due to limited high‐quality evidence.
Francesco Panzuto +7 more
wiley +1 more source
Acute effects of alloxan- and streptozotocin-induced insulin deficiency on somatostatin and glucagon secretion by the perfused isolated rat pancreatico-duodenal preparation [PDF]
Yasuo Goto +2 more
openalex +3 more sources

