Results 11 to 20 of about 128,394 (306)
Epilepsia Open, EarlyView., 2022 Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica +6 more
wiley +1 more source
Somatostatin and somatostatin receptors in retinal diseases [PDF]
European Journal of Endocrinology, 2000 Somatostatin is a small neuropeptide that is producedin the central nervous system, where it acts as aneurotransmitter. This neuropeptide also has animportant role in the neuroendocrine system as aninhibitor of hormone release, the most strikingexample of which is the inhibition of growth hormonerelease.
van, Hagen PM +7 more
openaire +5 more sources
BMC Infectious Diseases, 2005 Background The neuropeptide somatostatin is one of the major regulatory peptides in the central nervous system and the digestive tract. Our recent work has delineated an association between fibrosis and low levels of endogenous somatostatin plasma levels
Peeters Theo +4 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2022 Epileptic seizures result in pronounced over-expression of neuropeptide Y (NPY). In vivo and in vitro studies revealed that NPY exerts potent anticonvulsive actions through presynaptic Y2 receptors by suppressing glutamate release from principal neurons.
Meinrad Drexel, Günther Sperk
doaj +1 more source
Somatostatin receptor expression in parathyroid neoplasms
Endocrine Connections, 2019 Introduction: Parathyroid carcinoma represents a rare cause of primary hyperparathyroidism. Distinguishing carcinoma from the benign tumors underlying primary hyperparathyroidism remains challenging.
Sara Storvall +6 more
doaj +1 more source
E-cadherin expression is associated with somatostatin analogue response in acromegaly [PDF]
, 2019 Acromegaly is a rare disease resulting from hypersecretion of growth hormone (GH) and insulin‐like growth factor 1 (IGF1) typically caused by pituitary adenomas, which is associated with increased mortality and morbidity. Somatostatin analogues (SSAs)
Cano, David A. +10 more
core +1 more source
Frontiers in Oncology, 2022 Neuroendocrine neoplasms (NENs) comprise a heterogeneous collection of tumors derived from various neuroendocrine cells and are divided into functioning NEN and non-functioning NEN. Some NENs present with mild symptoms and can secrete somatostatin. These
Yuming Shao +5 more
doaj +1 more source
Neurochemical characterisation of lamina II inhibitory interneurons that express GFP in the PrP-GFP mouse [PDF]
, 2013 Background Inhibitory interneurons in the superficial dorsal horn play important roles in modulating sensory transmission, and these roles are thought to be performed by distinct functional populations. We have identified 4 non-overlapping classes among
Garzillo, F. +4 more
core +2 more sources
Reduced brain somatostatin in mood disorders: a common pathophysiological substrate and drug target?
Frontiers in Pharmacology, 2013 Our knowledge of the pathophysiology of affect dysregulation has progressively increased, but the pharmacological treatments remain inadequate. Here, we summarize the current literature on deficits in somatostatin, an inhibitory modulatory neuropeptide ...
Li-Chun eLin, Etienne eSibille
doaj +1 more source
Molecular and functional characterization of somatostatin-type signalling in a deuterostome invertebrate [PDF]
Open Biology, 2020 Somatostatin (SS) and allatostatin-C (ASTC) are structurally and evolutionarily related neuropeptides that act as inhibitory regulators of physiological processes in mammals and insects, respectively.
Ya Zhang +5 more
doaj +1 more source