Results 11 to 20 of about 179,431 (364)
Frontiers in Aging Neuroscience, 2021 Changes in the physiology, neurochemistry and structure of neurons, particularly of their dendritic spines, are thought to be crucial players in age-related cognitive decline. One of the most studied brain structures affected by aging is the hippocampus,
Yaiza Gramuntell +9 more
doaj +1 more source
Cellular mechanisms underlying central sensitization in a mouse model of chronic muscle pain
eLife, 2022 Chronic pain disorders are often associated with negative emotions, including anxiety and depression. The central nucleus of the amygdala (CeA) has emerged as an integrative hub for nociceptive and affective components during central pain development ...
Yu-Ling Lin +8 more
doaj +1 more source
Somatostatin and somatostatin receptors in retinal diseases [PDF]
European Journal of Endocrinology, 2000 Somatostatin is a small neuropeptide that is producedin the central nervous system, where it acts as aneurotransmitter. This neuropeptide also has animportant role in the neuroendocrine system as aninhibitor of hormone release, the most strikingexample of which is the inhibition of growth hormonerelease.
van, Hagen PM +7 more
openaire +5 more sources
Somatostatin Analogues in the Treatment of Neuroendocrine Tumors: Past, Present and Future [PDF]
, 2019 In recent decades, the incidence of neuroendocrine tumors (NETs) has steadily increased. Due to the slow-growing nature of these tumors and the lack of early symptoms, most cases are diagnosed at advanced stages, when curative treatment options are no ...
Amthauer, Holger +8 more
core +1 more source
Overview of Radiolabeled Somatostatin Analogs for Cancer Imaging and Therapy
Molecules, 2020 Identified in 1973, somatostatin (SST) is a cyclic hormone peptide with a short biological half-life. Somatostatin receptors (SSTRs) are widely expressed in the whole body, with five subtypes described. The interaction between SST and its receptors leads
Romain Eychenne +5 more
semanticscholar +1 more source
Somatostatin receptor expression in parathyroid neoplasms
Endocrine Connections, 2019 Introduction: Parathyroid carcinoma represents a rare cause of primary hyperparathyroidism. Distinguishing carcinoma from the benign tumors underlying primary hyperparathyroidism remains challenging.
Sara Storvall +6 more
doaj +1 more source
BMC Infectious Diseases, 2005 Background The neuropeptide somatostatin is one of the major regulatory peptides in the central nervous system and the digestive tract. Our recent work has delineated an association between fibrosis and low levels of endogenous somatostatin plasma levels
Peeters Theo +4 more
doaj +1 more source
The decrease in growth hormone (GH) response after repeated stimulation with GH-Releasing hormone is partly caused by an elevation of somatostatin tonus. [PDF]
, 1996 Repeated injection of GHRH leads to a decrease in the GH response in normal subjects. Arginine (Arg) stimulates GH secretion by suppression of hypothalamic somatostatin.
Mehltretter, Gerhard +5 more
core +1 more source
E-cadherin expression is associated with somatostatin analogue response in acromegaly [PDF]
, 2018 Acromegaly is a rare disease resulting from hypersecretion of growth hormone (GH) and insulin‐like growth factor 1 (IGF1) typically caused by pituitary adenomas, which is associated with increased mortality and morbidity. Somatostatin analogues (SSAs)
Cano, David A. +10 more
core +1 more source
Nature Communications, 2019 The formation and maintenance of spatial representations within hippocampal cell assemblies is strongly dictated by patterns of inhibition from diverse interneuron populations.
Matt Udakis +4 more
semanticscholar +1 more source