Results 21 to 30 of about 76,426 (249)
Frontiers in Endocrinology, 2020 Introduction: Acromegaly is a rare, serious endocrine disorder characterized by excess growth hormone (GH) secretion by a pituitary adenoma and overproduction of insulin-like growth factor I (IGF-I).
Mônica Gadelha +10 more
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Biochimica et Biophysica Acta (BBA) - Biomembranes, 2003 In 1972, Brazeau et al. isolated somatostatin (somatotropin release-inhibiting factor, SRIF), a cyclic polypeptide with two biologically active isoforms (SRIF-14 and SRIF-28). This event prompted the successful quest for SRIF receptors. Then, nearly a quarter of a century later, it was announced that a neuropeptide, to be named cortistatin (CST), had ...
Møller, Lars Neisig +3 more
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Somatostatin/somatostatin receptor signalling: Phosphotyrosine phosphatases [PDF]
Molecular and Cellular Endocrinology, 2008 Activation of phosphotyrosine phosphatases (PTPs) by somatostatin receptor (SSTR) represents one of the main intracellular mechanisms involved in the antiproliferative effect of somatostatin (SST) and analogues. Since their molecular cloning, the role of PTPs is emerging as a major regulator of different cell functions including cell proliferation ...
openaire +3 more sources
Frontiers in Molecular Neuroscience, 2020 Oxytocin, acting through the oxytocin receptor (Oxtr) in the periphery, is best known for its roles in regulating parturition and lactation. However, it is also now known to possess a number of important social functions within the central nervous system,
W. Scott Young, June Song
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Successful postoperative pancreatic fistula treatment with the use of somatostatin infusion after duodenal gastrointestinal stromal tumor resection [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2019 Introduction. According to the International Study Group on Pancreatic Fistula, a postoperative pancreatic fistula is defined as every case of fluid leak on the third (or later) postoperative day, in which the level of amylase in the collected fluid is ...
Chabowski Mariusz +6 more
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Poultry Science, 2021 : Melatonin (MEL) plays an important role in regulating growth and development of organisms and the cellular metabolism. This study was conducted to explore the role of MEL in mediating monochromatic light-induced secretion of somatostatin (SST) in the ...
Xiaojing Qin +7 more
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Archives of Endocrinology and MetabolismSUMMARY Hemangioblastomas associated with von Hippel-Lindau (VHL) disease are frequently multiple and recur during prolonged follow-up. Currently, no systemic treatment is available for these tumors.
Eloá Pereira Brabo +4 more
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Advanced Healthcare Materials, EarlyView.This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre +3 more
wiley +1 more source
Einstein (São Paulo), 2022 Objective To evaluate whether there is a significant difference in somatostatin analog uptake in meningiomas treated or not with radiation therapy.
Guilherme de Carvalho Campos Neto +10 more
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Advanced Science, EarlyView.Acute brain injuries are characterized by extensive tissue damage, resulting in debilitating deficits in patients. Despite considerable progress, cell‐based approaches have yet to identify an ideal candidate. This long‐term study explores the use of an untested cell source – human enteric glia – and a non‐invasive administration route – intranasal ...
Nina Colitti +11 more
wiley +1 more source