Results 41 to 50 of about 128,394 (306)
Archives of Endocrinology and MetabolismSUMMARY Hemangioblastomas associated with von Hippel-Lindau (VHL) disease are frequently multiple and recur during prolonged follow-up. Currently, no systemic treatment is available for these tumors.
Eloá Pereira Brabo +4 more
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Utility of Somatostatin Receptors in Gastrointestinal Tract and Pancreas Neuroendocrine Tumors
Namık Kemal Tıp Dergisi, 2020 Aim: Neuroendocrine tumors (NETs) are heterogenous group of tumors. Most of gastroenteropancreatic NETs (GEPNETs) are welldifferentiated low-grade tumors but a subset of them displays aggressive behavior.
Kivilcim Eren ERDOGAN +5 more
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Inhibitory neuron map of sevoflurane induced neurotoxicity model in young primates
Frontiers in Cellular Neuroscience, 2023 IntroductionSevoflurane, one of the most commonly used anesthetic agents in children, may induce neuronal dysfunction and cognitive impairment. Exposure to sevoflurane might induce an imbalance between neural excitation and inhibition which could be a ...
Yixuan Niu +5 more
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Advanced Science, EarlyView.This study integrates dual‐reporter genetics, imaging flow cytometry, and single‐cell sequencing to characterize rare bihormonal cells in mouse and human pancreatic islets. Gcg⁺Ins⁺ cells resemble α‐cells rather than transitional states. Cross‐species gene network analysis refines islet cell taxonomy and reveals human‐specific δ‐cell subtypes ...
Xin‐Xin Yu +10 more
wiley +1 more source
δ-Cells: The Neighborhood Watch in the Islet Community
Biology, 2021 Somatostatin-secreting δ-cells have aroused great attention due to their powerful roles in coordination of islet insulin and glucagon secretion and maintenance of glucose homeostasis.
Rui Gao, Tao Yang, Quan Zhang
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Cortistain is expressed in a distinct subset of cortical interneurons [PDF]
, 1997 Cortistatin is a presumptive neuropeptide that shares 11 of its 14 amino acids with somatostatin. In contrast to somatostatin, administration of cortistatin into the rat brain ventricles specifically enhances slow wave sleep, apparently by antagonizing ...
Alcántara Horrillo, Soledad +8 more
core
Somatostatin agonist pasireotide inhibits exercise stimulated growth in the male Siberian hamster (Phodopus sungorus) [PDF]
, 2017 R.Dumbell was supported by a University of Aberdeen PhD studentship and a research visit grant awarded by the British Society of Neuroendocrinology. Further support was provided by the Scottish Government Rural and Environment Science and Analytical ...
Barrett, P +6 more
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Advanced Science, EarlyView.The N1 peptide specifically targets neurons, enabling cytosolic delivery of fluorescent dyes and proteins for super‐resolution imaging and functional genetic modification. Abstract Efficient delivery of biomolecules into neurons has significant impacts on therapeutic applications in the central nervous system (CNS) and fundamental neuroscience research.
Xiaoqian Ge +16 more
wiley +1 more source
On implications of somatostatin in diabetic retinopathy
Neural Regeneration ResearchSomatostatin, a naturally produced neuroprotective peptide, depresses excitatory neurotransmission and exerts anti-proliferative and anti-inflammatory effects on the retina.
Yanhong Fang +5 more
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A scalable platform for the development of cell-type-specific viral drivers
eLife, 2019 Enhancers are the primary DNA regulatory elements that confer cell type specificity of gene expression. Recent studies characterizing individual enhancers have revealed their potential to direct heterologous gene expression in a highly cell-type-specific
Sinisa Hrvatin +10 more
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