Results 91 to 100 of about 117,026 (248)

Stimulation of insulin and somatostatin release by two meglitinide analogs.

, 1997
Several meglitinide analogs are currently under investigation as potential insulinotropic tools for the treatment of noninsulin-dependent diabetes. The present study aimed to further insight into the effect of these agents on the secretion of insulin ...
Fuhlendorff, J, Leclercq Meyer, Viviane, Malaisse, Willy, Ladrière, Laurence   +3 more
core   +1 more source

Formula for the progressive reintroduction of fat into breast milk in infants with chylothorax

JPGN Reports, EarlyView.
Abstract Chylothorax in infants is a potentially life‐threatening condition, often resulting from injury during cardiac surgery. Traditionally, breastfeeding is discontinued. Recently, feeding with defatted human milk has been safely introduced. However, methods for fat reintroduction are not standardized.
Sonia María Alonso‐Clemente, Ana Concheiro‐Guisan   +1 more
wiley   +1 more source

Perioperative Risks of Concurrent Pancreatic and Hepatic Resections for Neuroendocrine Tumors

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Pancreatic neuroendocrine tumors (pNETs) account for 1%–2% of pancreatic tumors, with an increasing incidence. The safety of concurrent pancreas‐liver resections remains uncertain. This study evaluated the national outcomes of concurrent pancreatectomy and liver‐directed surgery for pNETs. Methods ACS‐NSQIP (2019–2023)
Amir Ebadinejad, Ashrita Raghuram, Sophia Xiao, Ethan Angle, Hassan Aziz   +4 more
wiley   +1 more source

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

Medicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti, Camilla Tavani, Elena Somenza, Nicolas Tassone, Antonio d'Amati, Marta Turati, Roberto Ronca   +6 more
wiley   +1 more source

Treatment of neuroendocrine tumors with somatostatin analogs

, 2006
Neuroendocrine tumors constitute a group of hormone producing tumors originating from neuroendocrine cells in different organs. Most tumors have a low proliferation index measured by Ki67 and the progression of the tumor is slow.
Janson, Eva Tiensuu,
core   +1 more source

ENETS concensus guidelines for the standards of care in Neuroendocrine tumors: peptide receptor radionuclide therapy with radiolabeled somatostatin analogs [PDF]

, 2009
The purpose of this guideline is to assist physicians caring for patients with neuroendocrine tumors in considering eligibility criteria for peptide receptor radionuclide therapy (PRRT), and in defining the minimum requirements for PRRT.
Komminoth, P, European-Neuroendocrine-Tumor, Society, Kos-Kudla, B, de Herder, WW, Mallorca-Consensus-Conference, Participants, Lebtahi, R, Krenning, Eric, Kwekkeboom, DJ, de Herder, W.W., Krenning, EP, Plöckinger, U, Kwekkeboom, Dik   +11 more
core   +1 more source

Perioperative Outcomes of Patients With Pancreatic Neuroendocrine Neoplasms in the Context of Different Body Composition Phenotypes

World Journal of Surgery, EarlyView.
Pancreatic neuroendocrine neoplasms (pNEN) are rare and heterogeneous tumors with increasing incidence. While surgical resection remains the only curative treatment, perioperative outcomes are influenced by patient‐related risk factors. Recent research highlights body composition (BC) as a prognostic marker in oncological and transplantation surgery ...
Fabiola A. Bechtiger, Mariah Herbrich, Hazem K. A. A. Hassan, Jörg Kaiser, Thomas Hank, Magdalena Lewosinska, Deniz Uluk, Osman Öcal, Nicole D. Hildebrand, Steven WM Olde Damink, Franck Billmann, Zoltan Czigany, Mohammed Al‐Saeedi   +12 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

High-Dose Lanreotide in the Treatment of Poorly Differentiated Pancreatic Neuroendocrine Carcinoma: A Case Report

Case Reports in Oncology, 2014
Pancreatic neuroendocrine tumors (NETs), including poorly differentiated carcinomas (NECs), are rarely encountered. The majority of these tumors do not secrete excess hormones, but functioning NETs produce large amounts of vasoactive peptides and may ...
Frank Van Fraeyenhove, Nathalie Meireson, Luc Terriere, Paul Willemsen, Jan Kunnen, Caroline Mattelaer, Frank Van Acker, Dirk Schrijvers   +7 more
doaj   +1 more source

Induction of the somatostatin receptor on colon carcinoma cells as a target for radiolabeled or cytotoxic somatostatin analogs [PDF]

, 2003
__Abstract__ In 1973 Brazeau et al. isolated and identified a 14-amino acid peptide, named somatotropin-release inhibiting factor (SRIF), later changed to somatostatin (SS)(1).
Mearadji, A. (Amir)
core   +1 more source