Neuroendocrine tumors overexpress somatostatin receptors, which serve as important and unique therapeutic targets for well-differentiated advanced disease.
Mayank Patel +5 more
doaj +2 more sources
Background Merkel cell carcinoma (MCC) is an aggressive neuroendocrine skin tumor. Currently, 18F-fluoro-deoxy-glucose (18F-FDG) PET/CT is the functional imaging modality of choice. Few data are available on the use of 68Ga-somatostatin analogs.
Silvia Taralli +7 more
doaj +2 more sources
18F-Labeled Somatostatin Analogs as PET Tracers for the Somatostatin Receptor: Ready for Clinical Use [PDF]
Molecular imaging of the somatostatin receptor plays a key role in the clinical management of neuroendocrine tumors. PET imaging with somatostatin analogs (SSAs) labeled with 68Ga or 64Cu is currently the gold standard in clinical practice.
Hannes Leupe +7 more
openalex +2 more sources
Radiolabeled Somatostatin Analogs-A Continuously Evolving Class of Radiopharmaceuticals. [PDF]
Simple Summary Somatostatin receptors (SSTs) are of particular interest in oncology because these proteins are overexpressed on the cell membranes of different human malignancies, especially neuroendocrine tumors (NETs) and neuroendocrine neoplasms (NENs)
Fani M, Mansi R, Nicolas GP, Wild D.
europepmc +2 more sources
Meningiomas and Somatostatin Analogs: A Systematic Scoping Review on Current Insights and Future Perspectives. [PDF]
Tollefsen SE +3 more
europepmc +3 more sources
Real-World Experience With Pasireotide Lar in Acromegaly Resistant to First-Generation Somatostatin Analogs: A Single Center 1-Year Observation [PDF]
Stelmachowska-Banas M +3 more
europepmc +3 more sources
Somatostatin Analogs in Clinical Practice: a Review. [PDF]
Somatostatin analogs are an invaluable therapeutic option in the diagnosis and treatment of somatotropinomas, thyrotropinomas, and functioning and non-functioning gastroenteropancreatic neuroendocrine tumors.
Gomes-Porras M +2 more
europepmc +2 more sources
Synthetic somatostatin analogs beyond cancer. [PDF]
Barabutis N, Siejka A.
europepmc +3 more sources
The Antiproliferative Activity of High-Dose Somatostatin Analogs in Gastro-Entero-Pancreatic Neuroendocrine Tumors: A Systematic Review and Meta-Analysis. [PDF]
Panzuto F +7 more
europepmc +3 more sources
Biliary Stone Disease in Patients with Neuroendocrine Tumors Treated with Somatostatin Analogs: A Multicenter Study. [PDF]
BACKGROUND Somatostatin analogs (SSAs) are the mainstay of neuroendocrine tumor (NET) treatment. Biliary stone disease is reported as a common side effect of SSAs, with a frequency ranging from 10% to 63%.
Brighi N +16 more
europepmc +2 more sources

