Results 71 to 80 of about 158,858 (186)

Soluble Programmed Cell Death Protein 1 and Its Ligand: Potential Biomarkers to Predict Acute Kidney Injury After Surgery in Critically Ill Patients

open access: yesJournal of Inflammation Research, 2022
Jingyi Wang, Xi Zheng, Yijia Jiang, Huimiao Jia, Xiaocui Shi, Yue Han, Qingping Li, Wenxiong Li Surgical Intensive Care Unit, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Wenxiong Li, Surgical ...
Wang J   +7 more
doaj  

Regulation of Immune Checkpoints: From Molecular Mechanisms to Clinical Therapies

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by unleashing antitumor immunity. This review comprehensively examines the molecular mechanisms underlying key immune checkpoints—including PD‐1/PD‐L1, CTLA‐4, and TIM‐3—and their clinical applications.
Qintao Ge   +9 more
wiley   +1 more source

Prognostic value of soluble programmed death-1 and soluble programmed death ligand-1 in severe traumatic brain injury patients

open access: yesScientific Reports
Patients with traumatic brain injury (TBI) frequently exhibit concomitant immunosuppression. In this study, we evaluated the predictive values of soluble programmed death-1 (sPD-1) and soluble programmed death ligand-1 (sPD-L1) in patients with severe ...
Lei Liu   +9 more
doaj   +1 more source

Advancing Heliophysics and Space Weather Modeling Through Open Science

open access: yesSpace Weather, Volume 24, Issue 6, June 2026.
Abstract We present a community‐wide effort to develop a strategy and action plan to advance heliophysics and space weather modeling through open science. While open science has the potential to enhance the quality and pace of scientific discovery, its application to scientific modeling requires more careful consideration regarding open data and open ...
C. Corti   +87 more
wiley   +1 more source

The Change of Soluble Programmed Cell Death-Ligand 1 in Glioma Patients Receiving Radiotherapy and Its Impact on Clinical Outcomes

open access: yesFrontiers in Immunology, 2020
BackgroundThe programmed cell death ligand 1 (PD-L1) plays a key role in glioma development. However, due to the specificity of glioma’s anatomical position, the role of its expression as a tumor biomarker is limited.
Xing-Chen Ding   +11 more
doaj   +1 more source

Clinical Significance of Biomarkers in Oropharyngeal Squamous Cell Carcinoma: Recurrence Prediction and Treatment Response

open access: yesCancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Oropharyngeal squamous cell carcinoma (OPSCC) accounts for a substantial proportion of head and neck cancers, with a rising incidence largely driven by human papillomavirus (HPV) infection. Despite advances in multimodal treatment, disease recurrence remains common and limits long‐term survival, highlighting the need for reliable ...
Yunxia Chen   +7 more
wiley   +1 more source

Proteomic and Super‐Resolution Analyses of Murine Brown Adipocyte‐Derived Extracellular Vesicles

open access: yesJournal of Extracellular Biology, Volume 5, Issue 5, May 2026.
Graphical Abstract ABSTRACT Thermogenic brown adipocytes (BAs) are not only an energy sink but also regulate systemic metabolic health through secreted factors and extracellular vesicles (EVs). Here, we investigate the baseline profiles BA‐EVs and how cold‐induced thermogenesis alters the proteome of BA‐EVs.
Menchus Quan   +8 more
wiley   +1 more source

SPD Members Survey 1991

open access: yes, 1995
Judgement on the SPD by its members. Topics: Length of membership in the SPD as well as in the local committee; contact or cause for personally joining the party; manner of first contact on the part of the party after joining; evaluation of selected ...
SPD-Parteivorstand, Bonn
core   +1 more source

Image_2_The interaction between the soluble programmed death ligand-1 (sPD-L1) and PD-1+ regulator B cells mediates immunosuppression in triple-negative breast cancer.jpeg

open access: yes, 2022
Accumulating evidence suggests that regulatory B cells (Bregs) play important roles in inhibiting the immune response in tumors. Programmed death 1 (PD-1) and programmed death ligand 1 (PD-L1) are important molecules that maintain the balance of the ...
Sining Wang (8145588)   +12 more
core   +1 more source

Table_2_The interaction between the soluble programmed death ligand-1 (sPD-L1) and PD-1+ regulator B cells mediates immunosuppression in triple-negative breast cancer.docx

open access: yes, 2022
Accumulating evidence suggests that regulatory B cells (Bregs) play important roles in inhibiting the immune response in tumors. Programmed death 1 (PD-1) and programmed death ligand 1 (PD-L1) are important molecules that maintain the balance of the ...
Sining Wang (8145588)   +12 more
core   +1 more source

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