Results 91 to 100 of about 44,827 (196)

A New Kinetic‐Mechanistic Approach Towards Spectrophotometric Bioanalysis of 2‐Phenylethylamine as a Sympathomimetic Agent Using Sodium Isopropyl Xanthate

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT 2‐Phenylethylamine (2‐PEA), an aromatic biogenic amine, demonstrates significant physiological and toxicological effects on human health. A variety of conventional methods have been widely used for the determination of 2‐PEA. However, the necessity of complex sample preparation and high cost of instrumentation may pose challenges to their ...
Fatemeh Nami, Houman Kholafazad, Mohammad Hasanzadeh, Nasrin Shadjou   +3 more
wiley   +1 more source

Spermidine Inhibits M1 Microglia Polarization in a Mouse Model of Parkinson's Disease and BV2 Cells via NF‐κB/STAT‐1 Pathway

Brain and Behavior
Background Excessively activated M1 microglia release proinflammatory factors that can cause neuronal death and contribute to the development of Parkinson's disease (PD).
Jun Shu, Yuqiong Jiao, Wenshi Wei, Aijuan Yan   +3 more
doaj   +1 more source

A Combination of Xanthohumol and Ursolic Acid in the Diet Leads to Synergistic Inhibition of Prostate Cancer Progression

Molecular Carcinogenesis, Volume 65, Issue 4, Page 508-522, April 2026.
ABSTRACT Prostate cancer (PCa) is the second most common cancer and second leading cause of cancer death for American men. Chemoprevention by using phytochemicals offers a promising approach to improve outcomes due to their ability to act on cancer cell metabolism and growth while maintaining low toxicity profiles.
Rachel Clark, Achinto Saha, G. Lavender Hackman, Chelsea A. Friedman, Ruggiero Gorgoglione, Stefano Tiziani, John DiGiovanni   +6 more
wiley   +1 more source

Weight Loss During Obesity Provokes Asparaginase‐Associated Liver Steatosis and Endoplasmic Reticulum Stress

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Lean mice and DIO mice were fed either a low‐fat maintenance diet (MD) or a high‐fat obesogenic diet (OD) during pegylated asparaginase exposure. OD exacerbated asparaginase‐induced weight loss and modestly increased liver triglycerides and ER stress in lean mice.
Chintan T. Bhavsar, Brian A. Zalma, Keigo Tomoo, Yi Zhang, Esther M. Lopez, Emily T. Mirek, Joseph L. Dixon, Gregory C. Henderson, Ronald C. Wek, Tracy G. Anthony   +9 more
wiley   +1 more source

Metagenomic and biogenic amine changes in cassava fermentation for tucupi production using Pediococcus acidilactici starter culture

Journal of the Science of Food and Agriculture, Volume 106, Issue 4, Page 2424-2436, 15 March 2026.
Abstract BACKGROUND The use of starter cultures is essential for producing fermented foods with desirable standardized characteristics and for preventing pathogens. Pediococcus acidilactici, isolated from cocoa fermentation, was used in the production of tucupi, a widely appreciated sauce made from the juice of cassava root (manipueira) in the ...
Danielle Gama Brício, Maria Beatriz A Gloria, José Augusto Pires Bitencourt, Leandro Araujo Argôlo, Rafaela de Lima Ribeiro, Ilzane Abreu da Silva, Rosinelson da Silva Pena, Alessandra Santos Lopes, Gilson CA Chagas Junior, Nelson Rosa Ferreira   +9 more
wiley   +1 more source

Photoisomerization in Cyclic Dipeptide Derivatives: Photoswitchable Supramolecular Hydrogels and the Discovery of Hemipiperazine Photoswitches

ChemPhotoChem, Volume 10, Issue 3, March 2026.
Photoswitchable cyclic dipeptides (CDPs) can be used to prepare hydrogels that reversibly dissipate upon irradiation, or to photomodulate the development of living organisms. We report here applications and perspectives for CDPs containing azobenzene photoswitches or newly discovered hemipiperazine photoswitches in smart materials and biological ...
Zbigniew L. Pianowski
wiley   +1 more source

The Carbon Number‐specific Impact of Mineral Oil Saturated Hydrocarbons on Inducing Colonic Inflammation in Female and Male Fischer 344 Rats

Food Frontiers, Volume 7, Issue 2, March 2026.
MOSH‐induced colonic alterations and sex‐specific metabolic pathways in female and male F344 rats. ABSTRACT This study investigated the effects of mineral oil saturated hydrocarbon (MOSH) sub‐fractions (C20‐30 and C30‐50) on the colon of male and female F344 rats and the underlying mechanisms.
Lin Zhu, Mingming Zhang, Hong Zhang, Hai Zhang, Boyan Gao, Liangli (Lucy) Yu, Yaqiong Zhang   +6 more
wiley   +1 more source

Spermidine reduces ISGylation and enhances ISG15–USP18 interaction

Scientific Reports
The expression of ubiquitin-like molecule interferon-stimulated gene 15 kDa (ISG15) and its post-translational modification (ISGylation) are significantly activated by interferons or pathogen infections, highlighting their roles in innate immune ...
Haruka Etori, Riko Asoshina, Takayuki Obita, Fumihiko Okumura   +3 more
doaj   +1 more source

Iron, arginine, and redox metabolism in peripheral blood mononuclear cells distinguishes sickle cell disease and pulmonary hypertension

HemaSphere, Volume 10, Issue 3, March 2026.
Abstract Pulmonary hypertension (PH) is a severe vascular complication of sickle cell disease (SCD); yet, not all patients with SCD develop PH, and PH also arises independently. This duality underscores the need to understand their intersecting biology.
Francesca I. Cendali, Christina Lisk, Amy Argabright, Monika Dzieciatkowska, Nishant K. Rana, Delaney Swindle, Daniel Stephenson, Julie McAfee, Natalie Westover, Melissa Lucero, Aneta Gandjeva, Kurt Stenmark, Rubin Tuder, Brian B. Graham, Tim Lahm, Vijaya Karoor, Gemlyn George, Kathryn Hassel, Rachelle Nuss, Pavel Davizon‐Castillio, Paul W. Buehler, Angelo D'Alessandro, David C. Irwin   +22 more
wiley   +1 more source

Ions as Architects of DNA Nanostructures: Mechanisms, Simulations, and Technological Frontiers

Small Structures, Volume 7, Issue 3, March 2026.
Ions are not merely passive electrolytes but active regulators of DNA nanostructures. This review shows how ion valence, hydration, and specificity govern electrostatic screening, correlation, and confinement, enabling DNA origami, metallized DNA, nanopores, hydrogels, DNAzymes, molecular machines, and energy devices through integrated experimental and
Sergiy Perepelytsya, Dmytro Piatnytskyi, Tetiana Bubon, Narcis Cibotariu, Aatto Laaksonen, Francesca Mocci   +5 more
wiley   +1 more source