Results 101 to 110 of about 44,827 (196)
The FEBS Journal, Volume 293, Issue 5, Page 1323-1340, March 2026.Human SART3 has two RRM domains to engage with U6 snRNA for spliceosome recycling. This study reports solution structures of SART3 RRM domains and investigates the interaction between RRM and U6 snRNA. SART3 binds to the asymmetric bulge of U6 snRNA as a dimer via conserved positively charged surfaces.
Iktae Kim +8 more
wiley +1 more source
ODC1 Polyamine Metabolism Drives Prostate Cancer via AKT and Splicing
Journal of Cellular and Molecular Medicine, Volume 30, Issue 5, March 2026.ABSTRACT Prostate cancer is an aggressive disease with limited quantifiable biomarkers. One gene of interest is ODC1, which encodes ornithine decarboxylase, the rate‐limiting enzyme converting ornithine to putrescine in polyamine metabolism. Although ODC1 is known to be involved in prostate cancer development, exactly how it drives the disease ...
Jian Ma +6 more
wiley +1 more source
New Phytologist, Volume 249, Issue 6, Page 2652-2667, March 2026.Summary With the intensification of unpredictable flooding events because of global warming, there is a need to understand how root cells perceive and respond to oxygen deprivation. The use of high‐throughput single‐nuclei RNA‐sequencing (snRNA‐Seq) allows the examination of gene expression profiles in discrete cell types.
Robert D. Hill +5 more
wiley +1 more source
Plant Biotechnology Journal, Volume 24, Issue 3, Page 1152-1165, March 2026.ABSTRACT Low temperature triggers Ca2+ signalling and reprogramming of gene expression and metabolism in plants. However, how the Ca2+ signal is transduced to the downstream metabolic pathways remains unknown. The involvement of a cold‐induced calmodulin‐like protein, MfCML50, from Medicago falcata in regulation of cold tolerance was examined in the ...
Bohao Geng +6 more
wiley +1 more source
Effect of spermidine intake on skeletal muscle regeneration after chemical injury in male mice
Physiological ReportsSkeletal muscle has a high regenerative ability and maintains homeostasis by rapidly regenerating from frequent damage caused by intense exercise or trauma. In sports, skeletal muscle damage occurs frequently due to intense exercise, so practical methods
Tomohiro Iwata +4 more
doaj +1 more source
Macrocyclic spermidine and spermine alkaloids [PDF]
Pure and Applied Chemistry, 1973 M M, Badawi +10 more
openaire +2 more sources
Plant Biotechnology Journal, Volume 24, Issue 3, Page 1446-1464, March 2026.ABSTRACT Soil salinization threatens the yield and quality of wheat. Roots are critical for the salt stress response, yet their cell‐type‐specific mechanisms remain unclear. We conducted the first single‐nucleus RNA sequencing analysis of wheat root tips from salt‐sensitive (CS) and ‐tolerant (DK) varieties under salt stress, profiling 188 270 high ...
Lin Du +10 more
wiley +1 more source
Reducing the Sinapine Levels of Camelina sativa Seeds Through Targeted Genome Editing of REF1
Plant Biotechnology Journal, Volume 24, Issue 3, Page 1839-1865, March 2026.ABSTRACT Sinapine (O‐sinapoyl choline) is the major phenolic metabolite typically found in the oil‐rich seeds of Brassicaceae such as Camelina sativa and Brassica napus. It imparts a bitter taste to the seeds as a defence mechanism against herbivores, but it also renders them less palatable to livestock.
Amélie A. Kelly +5 more
wiley +1 more source