Results 21 to 30 of about 117,630 (212)
Chemosensors, 2022 Compared with traditional two-dimensional culture, a three-dimensional (3D) culture platform can not only provide more reliable prediction results, but also provide a simple, inexpensive and less time-consuming method compared with animal models.
Siwei Ding +5 more
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Micromachines, 2022 Spheroids are recognized for resembling the important characteristics of natural tumors in cancer research. However, the lack of controllability of the spheroid size, form, and density in conventional spheroid culture methods reduces the reproducibility ...
Neda Azizipour +5 more
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Current Research Trends in the Application of In Vitro Three-Dimensional Models of Liver Cells
Pharmaceutics, 2022 The liver produces and stores various nutrients that are necessary for the body and serves as a chemical plant, metabolizing carbohydrates, fats, hormones, vitamins, and minerals.
Chawon Yun, Sou Hyun Kim, Young-Suk Jung
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Recent Advances in Multicellular Tumor Spheroid Generation for Drug Screening
Biosensors, 2021 Multicellular tumor spheroids (MCTs) have been employed in biomedical fields owing to their advantage in designing a three-dimensional (3D) solid tumor model.
Kwang-Ho Lee, Tae-Hyung Kim
semanticscholar +1 more source
Current Issues in Molecular Biology, 2022 The expression of pluripotency factors, and their associations with clinicopathological parameters and drug response have been described in various cancers, including gastric cancer.
Han Thi Ngoc To +4 more
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Biomedicines, 2022 Aspects related to the response of cells to photodynamic therapy (PDT) have been well studied in cell cultures, which often grow in monolayers. In this work, we propose a spheroidal model of U87MG and SKBR3 cells designed to mimic superficial tumor ...
Viktória Pevná +7 more
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Regenerative Therapy, 2019 Suspension culture of three-dimensional (3D) spheroid of human induced pluripotent stem cells (hiPSCs) has been known as a potential method to enhance the scalability of hepatic differentiation of hiPSCs.
Fuad Gandhi Torizal +3 more
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Characterization of Triple-Negative Breast Cancer MDA-MB-231 Cell Spheroid Model
OncoTargets and Therapy, 2020 Background The tumor three-dimensional (3D) spheroid model in vitro is effective on detecting malignant cells and tumorigenesis, and assessing drug resistance.
Zhaoming Huang, YU Peng, Jia-Ning Tang
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Three-dimensional dynamics optical coherence tomography for tumor spheroid evaluation
Biomedical Optics Express, 2021 We present a completely label-free three-dimensional (3D) optical coherence tomography (OCT)-based tissue dynamics imaging method for visualization and quantification of the metabolic and necrotic activities of tumor spheroid.
Ibrahim Abd El-Sadek +7 more
semanticscholar +1 more source
Role of cellulose family in fibril organization of collagen for forming 3D cancer spheroids: In vitro and in silico approach [PDF]
BioImpacts, 2021 Introduction: Cell aggregation of three-dimensional (3D) culture systems (the so-called spheroids) are designed as in vitro platform to represent more accurately the in vivo environment for drug discovery by using semi-solid media.
Elaheh Dalir Abdolahinia +5 more
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