Results 21 to 30 of about 130,558 (351)

Current Research Trends in the Application of In Vitro Three-Dimensional Models of Liver Cells

Pharmaceutics, 2022
The liver produces and stores various nutrients that are necessary for the body and serves as a chemical plant, metabolizing carbohydrates, fats, hormones, vitamins, and minerals.
Chawon Yun, Sou Hyun Kim, Young-Suk Jung
doaj   +1 more source

Star Formation-Regulated Growth of Black Holes in Protogalactic Spheroids [PDF]

, 2000
The observed relation between central black hole mass and spheroid velocity dispersion is interpreted in terms of a self-regulation model that incorporates a viscous Keplerian accretion disk to feed the black hole, embedded in a massive, self-gravitating
Andreas Burkert, Duschl W. J., Joseph Silk, Silk J., White S.   +4 more
core   +2 more sources

Modulation of Spheroid Forming Capacity and TRAIL Sensitivity by KLF4 and Nanog in Gastric Cancer Cells

Current Issues in Molecular Biology, 2022
The expression of pluripotency factors, and their associations with clinicopathological parameters and drug response have been described in various cancers, including gastric cancer.
Han Thi Ngoc To, Qui Anh Le, Hang Thi Thuy Bui, Ji-Hong Park, Dongchul Kang   +4 more
doaj   +1 more source

Size-dependent hepatic differentiation of human induced pluripotent stem cells spheroid in suspension culture

Regenerative Therapy, 2019
Suspension culture of three-dimensional (3D) spheroid of human induced pluripotent stem cells (hiPSCs) has been known as a potential method to enhance the scalability of hepatic differentiation of hiPSCs.
Fuad Gandhi Torizal, Keiichi Kimura, Ikki Horiguchi, Yasuyuki Sakai   +3 more
doaj   +1 more source

Spheroidal Model of SKBR3 and U87MG Cancer Cells for Live Imaging of Caspase-3 during Apoptosis Induced by Singlet Oxygen in Photodynamic Therapy

Biomedicines, 2022
Aspects related to the response of cells to photodynamic therapy (PDT) have been well studied in cell cultures, which often grow in monolayers. In this work, we propose a spheroidal model of U87MG and SKBR3 cells designed to mimic superficial tumor ...
Viktória Pevná, Mariana Máčajová, Andrej Hovan, Gregor Bánó, Majlinda Meta, Boris Bilčík, Júlia Palková, Veronika Huntošová   +7 more
doaj   +1 more source

Inventions and Innovations in Preclinical Platforms for Cancer Research

Inventions, 2018
Three-dimensional (3D) cell culture systems can be regarded as suitable platforms to bridge the huge gap between animal studies and two-dimensional (2D) monolayer cell culture to study chronic diseases such as cancer.
Khashayar Moshksayan, Navid Kashaninejad, Mohammad Said Saidi   +2 more
doaj   +1 more source

The size and structure of the spheroid of IC 1613 [PDF]

, 2007
Nearby galaxies, spirals as well as irregulars, have been found to be much larger than previously believed. The structure of the huge spheroid surrounding dwarf galaxies could give clues to their past gravitational history.
Albert, Battinelli, Binggeli, Bland-Hawthorn, Caldwell, Caon, Demers, Dolphin, Evans, Hodge, Hoffman, Irwin, Kalirai, King, Lake, Magnier, Mateo, McConnachie, McConnachie, Oh, Oh, P. Battinelli, Pietrzynski, S. Demers, Smith, Stetson, Stetson, Stetson, Tikhonov, Vansevicius, Walcher, É. Artigau   +31 more
core   +3 more sources

New Models for a Triaxial Milky Way Spheroid and Effect on the Microlensing Optical Depth to the Large Magellanic Cloud [PDF]

, 2005
We obtain models for a triaxial Milky Way spheroid based on data by Newberg and Yanny. The best fits to the data occur for a spheroid center that is shifted by 3kpc from the Galactic Center.
Ansari R, C Savage, Dahn C C Liebert J Harris H C Guetter H H Tinney C G, Dehnen W, Freese K Fields B Graff D, Gould A, H J Newberg, K Freese, Lasserre T, Newberg H J, Newberg H J Yanny B, Ostriker J P, P Gondolo, Rohlfs K, Scalo J M, Sommer-Larsen J, Sutherland W, Udalski A, Udalski A, Weinberg M   +19 more
core   +3 more sources

High-throughput three-dimensional spheroid tumor model using a novel stamp-like tool

Journal of Tissue Engineering, 2019
Spheroid culture is a widely used three-dimensional culture technology that simulates the three-dimensional structure of tumors in vivo and has been considered a good model for tumor research.
Wei Liao, Jieqing Wang, Jiecheng Xu, Fuyu You, Mingxin Pan, Xiaoping Xu, Jun Weng, Xu Han, Shao Li, Yang Li, Kangyan Liang, Qing Peng, Yi Gao   +12 more
doaj   +1 more source

Role of cellulose family in fibril organization of collagen for forming 3D cancer spheroids: In vitro and in silico approach [PDF]

BioImpacts, 2021
Introduction: Cell aggregation of three-dimensional (3D) culture systems (the so-called spheroids) are designed as in vitro platform to represent more accurately the in vivo environment for drug discovery by using semi-solid media.
Elaheh Dalir Abdolahinia, Behzad Jafari, Sepideh Parvizpour, Jaleh Barar, Samad Nadri, Yadollah Omidi   +5 more
doaj   +1 more source