Results 81 to 90 of about 117,630 (212)
Inventions and Innovations in Preclinical Platforms for Cancer Research
Inventions, 2018 Three-dimensional (3D) cell culture systems can be regarded as suitable platforms to bridge the huge gap between animal studies and two-dimensional (2D) monolayer cell culture to study chronic diseases such as cancer.
Khashayar Moshksayan +2 more
doaj +1 more source
The Astrophysical Journal, 2000 We present evidence that nearly half of the dwarf spheroidal galaxies (dSph and dSph/dIrr) in the Local Group are associated with large reservoirs of atomic gas, in some cases larger than the stellar mass. The gas is sometimes found at large distance (~10 kpc) from the center of a galaxy and is not necessarily centered on it. Similarly large quantities
Blitz, Leo, Robishaw, Timothy
openaire +2 more sources
Effect of Spheroidal Age on Sorafenib Diffusivity and Toxicity in a 3D HepG2 Spheroid Model
Scientific Reports, 2019 The enhanced predictive power of 3D multi-cellular spheroids in comparison to conventional monolayer cultures makes them a promising drug screening tool.
Christoph Eilenberger +4 more
semanticscholar +1 more source
A Simple Model to Study Mosaic Gene Expression in 3D Endothelial Spheroids
Journal of Cardiovascular Development and DiseaseAims: The goal of this study was to establish a simple model of 3D endothelial spheroids with mosaic gene expression using adeno-associated virus (AAV) transduction, with a future aim being to study the activity of post-zygotic mutations common to ...
Lucinda S. McRobb +3 more
doaj +1 more source
BioengineeringThis study aimed to evaluate the osteogenic potential of mesenchymal stromal cell (MSC) spheroids combined with the basic fibroblast growth factor (bFGF) in a mouse femur fracture model.
Kugo Takeda +9 more
doaj +1 more source
Frontiers in MicrobiologyThe present study investigated the synthesis and biological applications of green, economical, and multifunctional silver and gold nanoparticles (TSAgNPs and TSAuNPs) using the ethnomedical important medicinal plant Thespesia lampas for biological ...
Sunayana Nath +5 more
doaj +1 more source
Frontiers in ToxicologyThere are currently no available cell lines for the ecologically relevant colonial waterbird species, the double-crested cormorant (DCCO). DCCOs are high trophic level aquatic birds that are used for routine contaminant monitoring programs in the ...
Tasnia Sharin +2 more
doaj +1 more source
Differences of statin activity in 2D and 3D pancreatic cancer cell cultures
Drug Design, Development and Therapy, 2017 Miglė Paškevičiūtė,1 Vilma Petrikaitė1,21Department of Drug Chemistry, Faculty of Pharmacy, Lithuanian University of Health Sciences, Kaunas, Lithuania; 2Department of Biothermodynamics and Drug Design, Vilnius University Institute of ...
Paškevičiūtė M, Petrikaitė V
doaj
Marine DrugsTriple-negative breast cancers (TNBC) lack estrogen, progesterone, and express little, if any, HER2 receptors on their surface. No targeted therapies exist for this aggressive form of breast cancer.
Esther A. Guzmán +3 more
doaj +1 more source