Results 31 to 40 of about 9,343 (242)
A fluorescent assay for ceramide synthase activity
Journal of Lipid Research, 2012 The sphingolipids are a diverse family of lipids with important roles in membrane compartmentalization, intracellular signaling, and cell-cell recognition. The central sphingolipid metabolite is ceramide, formed by the transfer of a variable length fatty
Hyun Joon Kim +4 more
doaj +1 more source
Cross-Platform Comparison of Untargeted and Targeted Lipidomics Approaches on Aging Mouse Plasma. [PDF]
, 2018 Lipidomics - the global assessment of lipids - can be performed using a variety of mass spectrometry (MS)-based approaches. However, choosing the optimal approach in terms of lipid coverage, robustness and throughput can be a challenging task.
Brunet, Anne +6 more
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Journal of Lipid Research, 2008 “Sphingosin” was first described by J. L. W. Thudichum in 1884 and structurally characterized as 2S,3R,4E-2-aminooctadec-4-ene-1,3-diol in 1947 by Herb Carter, who also proposed the designation of “lipides derived from sphingosine as sphingolipides ...
Sarah T. Pruett +7 more
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Mycotoxin occurrence in maize silage : a neglected risk for bovine gut health? [PDF]
, 2019 Forages are important components of dairy cattle rations but might harbor a plethora of mycotoxins. Ruminants are considered to be less susceptible to the adverse health effects of mycotoxins, mainly because the ruminal microflora degrades certain ...
Antonissen, Gunther +6 more
core +2 more sources
Altered Levels of Sphingosine and Sphinganine in Psoriatic Epidermis [PDF]
Annals of Dermatology, 2013 Ceramides are the main lipid component of the stratum corneum and are a structurally heterogeneous and complex group of sphingolipids of which sphingoid bases are the basic structural constituents. Altered levels of sphingoid bases have been reported in skin conditions that involve dryness and barrier disruption, including atopic dermatitis.The purpose
Moon, Sung-Hyuk +5 more
openaire +2 more sources
My journey in the discovery of nucleotide sugar transporters of the Golgi apparatus [PDF]
, 2018 Indexación: Scopus.I decided to do a second, 2-year postdoc in Phil Robbins’ lab at MIT. I applied for a 1-year extension of my Jane Coffin Childs Memorial Fund for Medical Research Fellowship and was advised by the director that while this was not ...
Hirschberg, C.B.
core +1 more source
The plant disease resistance gene Asc-1 prevents disruption of sphingolipid metabolism during AAL-toxin-induced programmed cell death [PDF]
, 2002 The nectrotrophic fungus Alternaria alternata f.sp. lycopersici infects tomato plants of the genotype asc/asc by utilizing a host-selective toxin, AAL-toxin, that kills the host cells by inducing programmed cell death.
Hille, J +4 more
core +12 more sources
Sphingolipid Metabolism Perturbations in Rett Syndrome
Metabolites, 2019 Rett syndrome is a severe neurodevelopmental disorder affecting mostly females and is caused by loss-of-function mutations in the MECP2 gene that encoded the methyl-CpG-binding protein 2.
Gerarda Cappuccio +6 more
doaj +1 more source
Glucose Reaction with Fumonisin B1 Partially Reduces Its Toxicity in Swine [PDF]
, 2004 Acute and subacute intraperitoneal doses of fumonisin B1 (FB1) were administered to test the efficacy of the FB1-glucose reaction products in detoxifying FB1 in swine.
Fernandez-Surumay, Guillermo +6 more
core +3 more sources
Frontiers in Cellular and Infection Microbiology, 2022 Children are at high risk for influenza A virus (IAV) infections, which can develop into severe illnesses. However, little is known about interactions between the microbiome and respiratory tract metabolites and their impact on the development of IAV ...
Qian Hu +6 more
doaj +1 more source