Results 11 to 20 of about 8,836 (207)

Effect of the multifunctional cosmetic ingredient sphinganine on hair loss in men and women with diffuse hair reduction

Clinical, Cosmetic and Investigational Dermatology, 2016
Nicole Gerlach,1,* Matthias Mentel,2,* Tim Köhler,2 Benjamin Tuchscherer,2 Birgit Garbe,1 Jasmina Ülker,1 Hagen Tronnier,1 Ulrike Heinrich,1 Mike Farwick2 1DermaTronnier GmbH & Co. KG, Institute for Experimental Dermatology, Witten/Herdecke
Gerlach N, Mentel M, Köhler T, Tuchscherer B, Garbe B, Ülker J, Tronnier H, Heinrich U, Farwick M   +8 more
doaj   +1 more source

Persistence of HCV in Acutely-Infected Patients Depletes C24-Ceramide and Upregulates Sphingosine and Sphinganine Serum Levels

International Journal of Molecular Sciences, 2016
Hepatitis C virus (HCV) substantially affects lipid metabolism, and remodeling of sphingolipids appears to be essential for HCV persistence in vitro.
Georgios Grammatikos, J. Dietz, N. Ferreirós, A. Koch, G. Dultz, Dimitra Bon, I. Karakasiliotis, T. Lutz, G. Knecht, Peter Gute, Eva Herrmann, S. Zeuzem, Penelope Mavromara, C. Sarrazin, Josef Pfeilschifter   +14 more
semanticscholar   +2 more sources

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

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Despite the availability of antiviral drugs and vaccines, respiratory viral infections remain a serious global health burden. To identify novel therapeutic candidates, we performed metabolomic profiling comparing serum from patients infected with ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
doaj   +2 more sources

Preparation of anti-Vicinal Amino Alcohols: Asymmetric Synthesis of d-erythro-Sphinganine, (+)-Spisulosine, and d-ribo-Phytosphingosine [PDF]

Journal of Organic Chemistry, 2013
Two variations of the Overman rearrangement have been developed for the highly selective synthesis of anti-vicinal amino alcohol natural products. A MOM ether-directed palladium(II)-catalyzed rearrangement of an allylic trichloroacetimidate was used as ...
Ewen D. D. Calder, Ahmed M. Zaed, A. Sutherland   +2 more
semanticscholar   +2 more sources

Correction to "Overexpression of FBR41 Enhances Resistance to Sphinganine Analog Mycotoxin-Induced Cell Death and Alternaria Stem Canker in Tomato". [PDF]

Plant Biotechnol J
Plant Biotechnology Journal, Volume 24, Issue 9, Page 5241-5241, September 2026.
europepmc   +2 more sources

Identification and characterization of 3-ketosphinganine reductase activity encoded at the BT_0972 locus in Bacteroides thetaiotaomicron

Journal of Lipid Research, 2022
Bacterial sphingolipid synthesis is important for the fitness of gut commensal bacteria with an implied potential for regulating mammalian host physiology.
Min-Ting Lee, Henry H. Le, Kevin R. Besler, Elizabeth L. Johnson   +3 more
doaj   +1 more source

Characterization of a Bacterial Kinase That Phosphorylates Dihydrosphingosine to Form dhS1P

Microbiology Spectrum, 2022
Like other members of the phylum Bacteroidetes, the oral anaerobe Porphyromonas gingivalis synthesizes a variety of sphingolipids, similar to its human host.
Dev K. Ranjit, Zachary D. Moye, Fernanda G. Rocha, Gregory Ottenberg, Frank C. Nichols, Hey-Min Kim, Alejandro R. Walker, Frank C. Gibson, Mary E. Davey   +8 more
doaj   +1 more source

Strong Alterations in the Sphingolipid Profile of Chickens Fed a Dose of Fumonisins Considered Safe

Toxins, 2021
Fumonisins (FB) are mycotoxins known to exert most of their toxicity by blocking ceramide synthase, resulting in disruption of sphingolipid metabolism.
Didier Tardieu, Maria Matard-Mann, Pi Nyvall Collén, Philippe Guerre   +3 more
doaj   +1 more source

Effects of Fumonisin-Contaminated Corn on Growth Performance of 9 to 28 kg Nursery Pigs

Toxins, 2020
Fumonisin contamination in corn is an emerging issue in animal feed production. Fumonisin disrupts the metabolism of sphingolipids and reduces growth performance.
Zhong-Xing Rao, Mike D. Tokach, Jason C. Woodworth, Joel M. DeRouchey, Robert D. Goodband, Hilda I. Calderón, Steve S. Dritz   +6 more
doaj   +1 more source

Altered Levels of Sphingosine, Sphinganine and Their Ceramides in Atopic Dermatitis Are Related to Skin Barrier Function, Disease Severity and Local Cytokine Milieu

International Journal of Molecular Sciences, 2020
Dysfunctional skin barrier plays a key role in the pathophysiology of atopic dermatitis (AD), a common inflammatory skin disease. Altered composition of ceramides is regarded as a major cause of skin barrier dysfunction, however it is not clear whether ...
R. J. Toncic, I. Jakaša, S. L. Hadžavdić, S. Goorden, Karen Jm Ghauharali-van der Vlugt, Femke S Stet, A. Balić, M. Petković, B. Pavičić, K. Žužul, B. Marinovic, S. Kežić   +11 more
semanticscholar   +1 more source