Results 21 to 30 of about 48,095 (292)
The Manifold Roles of Sphingolipids in Viral Infections
Frontiers in Physiology, 2021 Sphingolipids are essential components of eukaryotic cells. In this review, we want to exemplarily illustrate what is known about the interactions of sphingolipids with various viruses at different steps of their replication cycles.
Elita Avota +5 more
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Ethylene modulates sphingolipid synthesis in Arabidopsis
Frontiers in Plant Science, 2015 Sphingolipids have essential structural and bioactive functions in membranes and in signaling. However, how plants regulate sphingolipid biosynthesis in the response to stress remains unclear.
Jian-xin eWu +4 more
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Frontiers in Oncology, 2021 Prostate cancer is the second most prevalent malignancy worldwide. In the early stages, the development of prostate cancer is dependent on androgens. Over time with androgen deprivation therapy, 20% of prostate cancers progress to a castration-resistant ...
I Gusti Md Gde Surya C. Trapika +18 more
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Frontiers in Immunology, 2021 Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects females more than males, with African Americans developing more severe manifestation of the disease.
Samar M. Hammad +6 more
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Frontiers in Cardiovascular Medicine, 2021 Aortic dissection (AD) is a catastrophic cardiovascular emergency with a poor prognosis, and little preceding symptoms. Abnormal lipid metabolism is closely related to the pathogenesis of AD.
Huang Huang +14 more
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Toxins2-Amino-14,16-dimethyloctadecan-3-ol (AOD) is commonly found in foods contaminated with Fusarium avenaceum, particularly cereals or fruits, and is structurally related to Fusarium mycotoxins (fumonisins) and mammalian sphingoid bases, especially 1 ...
Shenlong Mo +7 more
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Circulating sphingolipids in heart failure
Frontiers in Cardiovascular Medicine, 2023 Lack of significant advancements in early detection and treatment of heart failure have precipitated the need for discovery of novel biomarkers and therapeutic targets.
Anna Kovilakath +3 more
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Biomolecules, 2020 Glioblastoma (GBM) is a primary malignant brain tumor with a dismal prognosis, partially due to our inability to completely remove and kill all GBM cells. Rapid tumor recurrence contributes to a median survival of only 15 months with the current standard
Cyntanna C. Hawkins +3 more
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Altered expression of glycobiology-related genes in Parkinson’s disease brain
Frontiers in Molecular Neuroscience, 2022 The precise mechanisms initiating and perpetuating the cellular degeneration in Parkinson’s disease (PD) remain unclear. There is decreased expression of the main brain gangliosides, and GM1 ganglioside in particular, in the PD brain along with decreased
Jay S. Schneider, Garima Singh
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Identification of Plasma Glycosphingolipids as Potential Biomarkers for Prostate Cancer (PCa) Status
Biomolecules, 2020 Prostate cancer (PCa) is the most common male cancer and the second leading cause of cancer death in United States men. Controversy continues over the effectiveness of prostate-specific antigen (PSA) for distinguishing aggressive from indolent PCa. There
Ashley J. Snider +16 more
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